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GENE：TGFB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TGFB1
FullNmae transforming growth factor beta 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11766
EnsembleID ENSG00000105329
Uniprot P01137

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TGFB1 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TGFB1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TGFB1 immunogenic 36579538 Through literature reviews, a total of 108 ICD-related genes were identified (Supplement Table S1). retulator signature
TGFB1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TGFB1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TGFB1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TGFB1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TGFB1 GO:0001570,GO:0001837,GO:0001843,GO:0001933,GO:0001934,GO:0002040,GO:0002062,GO:0002244,GO:0002248,GO:0002859,GO:0003179,GO:0003180,GO:0003823,GO:0005114,GO:0005114,GO:0005114,GO:0005125,GO:0005125,GO:0005125,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0005615,GO:0005634,GO:0005737,GO:0005796,GO:0005886,GO:0005902,GO:0006611,GO:0006754,GO:0006796,GO:0007173,GO:0007179,GO:0007179,GO:0007179,GO:0007179,GO:0007179,GO:0007435,GO:0007507,GO:0008083,GO:0008284,GO:0008284,GO:0008285,GO:0008285,GO:0009611,GO:0009986,GO:0010575,GO:0010628,GO:0010628,GO:0010628,GO:0010628,GO:0010629,GO:0010629,GO:0010629,GO:0010716,GO:0010718,GO:0010718,GO:0010742,GO:0010763,GO:0010800,GO:0010936,GO:0014008,GO:0016202,GO:0017015,GO:0019899,GO:0021915,GO:0022408,GO:0030214,GO:0030308,GO:0030334,GO:0030335,GO:0030335,GO:0031012,GO:0031093,GO:0031293,GO:0031334,GO:0032355,GO:0032570,GO:0032740,GO:0032755,GO:0032760,GO:0032801,GO:0032930,GO:0032967,GO:0032967,GO:0032967,GO:0033138,GO:0034713,GO:0034713,GO:0034714,GO:0034714,GO:0035307,GO:0035800,GO:0036446,GO:0042127,GO:0042306,GO:0042307,GO:0042802,GO:0043117,GO:0043406,GO:0043536,GO:0043537,GO:0043552,GO:0045066,GO:0045216,GO:0045596,GO:0045599,GO:0045662,GO:0045786,GO:0045892,GO:0045893,GO:0045893,GO:0045944,GO:0048298,GO:0048535,GO:0048642,GO:0048661,GO:0050680,GO:0050680,GO:0050714,GO:0050729,GO:0050731,GO:0050921,GO:0051092,GO:0051247,GO:0051781,GO:0051897,GO:0055010,GO:0060312,GO:0060312,GO:0060390,GO:0060391,GO:0060391,GO:0061912,GO:0062023,GO:0070168,GO:0070374,GO:0070723,GO:0071404,GO:0071456,GO:0071560,GO:0071560,GO:0071895,GO:0072562,GO:0085029,GO:0090263,GO:0090263,GO:0097191,GO:1900126,GO:1900182,GO:1901203,GO:1901203,GO:1901203,GO:1901666,GO:1902462,GO:1902894,GO:1902895,GO:1903077,GO:1904894,GO:1990402,GO:2000343,GO:2000353,GO:2000636,GO:2000679,GO:2000727

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TGFB1 hsa:7040 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa04068 FoxO signaling pathway - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa04110 Cell cycle - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa04148 Efferocytosis - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa04218 Cellular senescence - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa04390 Hippo signaling pathway - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa04672 Intestinal immune network for IgA production - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa04926 Relaxin signaling pathway - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa04932 Non-alcoholic fatty liver disease - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05140 Leishmaniasis - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05142 Chagas disease - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05144 Malaria - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05145 Toxoplasmosis - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05146 Amoebiasis - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05152 Tuberculosis - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05161 Hepatitis B - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05200 Pathways in cancer - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05210 Colorectal cancer - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05211 Renal cell carcinoma - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05212 Pancreatic cancer - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05220 Chronic myeloid leukemia - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05226 Gastric cancer - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05321 Inflammatory bowel disease - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05323 Rheumatoid arthritis - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05410 Hypertrophic cardiomyopathy - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05414 Dilated cardiomyopathy - Homo sapiens (human)
TGFB1 hsa:7040 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TGFB1 TGFBR2 10678166 11013220 11133108 11157754 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16446785 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21071413 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23331499 23784029 24132110 24336330 24403530 26192618 26201938 26966341 2871107 7594497 8515656 9311995 9865696 interaction type,stimulation N/A ACSN,SignaLink,SignaLink
TGFB1 TGFBR1 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26192618 26201938 26966341 2871107 7594497 8515656 9311995 9865696 interaction type N/A ACSN
TGFB1 PARD6A 11133108 14557817 15265520 15548370 15761148 15761153 16474430 17934056 19010789 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22315516 22703233 22949611 24132110 24336330 26192618 7594497 interaction type N/A ACSN
TGFB1 LTBP1 10025398 10544215 11133108 11766992 14557817 15548370 15611103 16139227 16474430 16710477 17934056 18342983 18423981 18802007 19010789 19109155 19741094 19854168 19909365 19920116 20519943 20535745 20644162 21278795 21883891 21900405 21909923 22703233 23620508 25732845 26192618 26552706 26711338 7594497 8570922 9314552 9931372 interaction type N/A ACSN
TGFB1 ITGA3 10671552 11133108 11348595 11955436 11967263 12051714 12426320 14557817 15001769 15279786 15548370 16039586 16099633 16371504 16474430 17143292 17303408 17660363 17928543 17934056 17936032 18037882 18590585 19010789 19029934 19109155 19171760 19619488 19734908 19920116 20519943 20644162 20705860 21278795 21666923 21900405 22007144 22174153 22203675 22674073 22703233 23343194 24023259 25730849 26192618 7542250 7575488 7594497 8666229 interaction type N/A ACSN
TGFB1 SMAD7 11133108 11708773 12490555 14557817 15111329 15181457 15252039 15548370 16474430 16607286 16716598 17615296 17934056 18403754 19010789 19109155 19920116 20519943 20644162 21041997 21278795 21900405 21909923 22703233 26192618 7594497 9157999 9335507 interaction type N/A ACSN
TGFB1 SMAD2 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 26192618 7594497 9311995 9865696 interaction type N/A ACSN
TGFB1 SMAD3 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 26192618 7594497 9311995 9865696 interaction type N/A ACSN
EMILIN1 TGFB1 14557817 16474430 17934056 20519943 21900405 2190045 26192618 interaction type N/A ACSN
FURIN TGFB1 14557817 16474430 17934056 20519943 21900405 26192618 interaction type N/A ACSN
MMP2 TGFB1 21900405 23691193 24376839 26192618 interaction type N/A ACSN
MMP9 TGFB1 21900405 26192618 interaction type N/A ACSN
THBS1 TGFB1 10657674 11982756 14568985 14996710 21900405 22943793 26192618 8349738 interaction type N/A ACSN
MMP13 TGFB1 21900405 26192618 interaction type N/A ACSN
MMP14 TGFB1 21900405 21909923 23691193 24376839 26192618 interaction type N/A ACSN
TGFB1 ETS1 11133108 11708773 12490555 14557817 15111329 15181457 15252039 15548370 16474430 16607286 16716598 17615296 17934056 18403754 19010789 19109155 19920116 20519943 20644162 21041997 21278795 21900405 21909923 22703233 26192618 7594497 9157999 9335507 interaction type N/A ACSN
TGFB1 TRAF6 11013220 11133108 12154066 12717440 12724770 12767520 12809600 14557817 15265520 15548370 16474430 17673906 17934056 18758450 18922473 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 22943793 24132110 24336330 26192618 7594497 9865696 interaction type N/A ACSN
MYC TGFB1 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027 26192618 interaction type N/A ACSN
FOS TGFB1 15067049 15749884 16243976 16327802 16393692 16394015 16413922 16713974 17404308 17485448 19667062 20547845 21372296 21385848 22634314 23390297 23430059 26192618 9064320 interaction type N/A ACSN
HMGB1 TGFB1 10952726 11672593 12646658 12803886 15802534 16267105 16327802 19931333 21372296 22842346 26192618 26618107 27048821 27192565 interaction type N/A ACSN
TGFB1 SRC 10671552 11133108 11348595 11476890 11955436 11967263 12051714 12426320 14557817 15001769 15279786 15548370 16039586 16099633 16371504 16474430 16919435 17143292 17303408 17496910 17517963 17660363 17928543 17934056 17936032 18037882 18590585 19010789 19029934 19109155 19171760 19619488 19734908 19920116 20519943 20644162 20705860 21278795 21666923 21900405 22007144 22174153 22203675 22370635 22674073 22703233 23343194 24023259 25572304 25730849 26192618 26552706 27216177 7542250 7575488 7594497 8666229 interaction type N/A ACSN
TGFB1 TGFB1 11331591 1310899 16885528 22326956 22703233 26467481 bind,up-regulates activity,down-regulates quantity by repression,transcriptional regulation N/A Signor
ITGB8 TGFB1 11970960 20870411 23331499 stimulation N/A SignaLink
ITGB6 TGFB1 20870411 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 TGFB1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC TGFB1 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 TGFB1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TGFB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TGFB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TGFB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TGFB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ASH1L TGFB1 22488473 trascriptional regulation,stimulation inferred by curator TFlink
FOSB TGFB1 10843986 trascriptional regulation,stimulation inferred by curator TFlink
FOSL2 TGFB1 10843986 trascriptional regulation,stimulation inferred by curator TFlink
JUND TGFB1 10843986 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 TGFB1 16365456 trascriptional regulation,stimulation inferred by curator TFlink
SMAD3 TGFB1 19214138 trascriptional regulation,stimulation inferred by curator TFlink
SMAD4 TGFB1 21968601 trascriptional regulation,stimulation inferred by curator TFlink
SMAD7 TGFB1 19214138 trascriptional regulation,stimulation inferred by curator TFlink
SP1 TGFB1 22415074 2808430 9580699 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 TGFB1 22415074 2808430 9580699 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 TGFB1 16474852 trascriptional regulation,stimulation inferred by curator TFlink
USF1 TGFB1 14757763 trascriptional regulation,stimulation inferred by curator TFlink
USF2 TGFB1 14757763 15184388 trascriptional regulation,stimulation inferred by curator TFlink
AR TGFB1 N/A trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TGFB1 N/A trascriptional regulation,stimulation inferred by curator TFlink
CEBPB TGFB1 N/A trascriptional regulation,stimulation inferred by curator TFlink
CREB1 TGFB1 N/A trascriptional regulation,stimulation inferred by curator TFlink
FOS TGFB1 N/A trascriptional regulation,stimulation inferred by curator TFlink
JUN TGFB1 N/A trascriptional regulation,stimulation inferred by curator TFlink
PPARA TGFB1 N/A trascriptional regulation,stimulation inferred by curator TFlink
RARA TGFB1 N/A trascriptional regulation,stimulation inferred by curator TFlink
SP3 TGFB1 N/A trascriptional regulation,stimulation inferred by curator TFlink
TP53 TGFB1 N/A trascriptional regulation,stimulation inferred by curator TFlink
WT1 TGFB1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002E92A8 TGFB1 21991303 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00004929F1 TGFB1 22393947 25416803 27624777 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000009262D TGFB1 18591254 25416803 26383248 mrna cleavage,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr TarBase
URS00000EC1BE TGFB1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000044FD7 TGFB1 23726841 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00002075FA TGFB1 23433743 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS00000DDD35 TGFB1 24367666 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS000005481D TGFB1 24367666 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS00003380CC TGFB1 24168656 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS0000315338 TGFB1 24801815 25416803 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000272039 TGFB1 25416803 26498065 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS000027464B TGFB1 25416803 26417995 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001EFBE3 TGFB1 25416803 28337286 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001CF056 TGFB1 25416803 28042090 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000041CB9C TGFB1 25416803 27499071 mrna cleavage,inhibition western blot TarBase
URS00001123BD TGFB1 25416803 27273381 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS000039E1E1 TGFB1 25416803 25950430 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS00002367FA TGFB1 25416803 28259900 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
DCN TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 DCN 25361965 interaction type N/A PTMCode2
MMP2 TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 MMP2 25361965 interaction type N/A PTMCode2
TGFB1 ITGB8 25361965 interaction type N/A PTMCode2
ITGB8 TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 VTN 25361965 interaction type N/A PTMCode2
VTN TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 SPARC 25361965 interaction type N/A PTMCode2
SPARC TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 THBS1 25361965 interaction type N/A PTMCode2
THBS1 TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 ITGAV 25361965 interaction type N/A PTMCode2
ITGAV TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 ACVRL1 25361965 interaction type N/A PTMCode2
ACVRL1 TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 TP53 25361965 interaction type N/A PTMCode2
TP53 TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 ITGB6 25361965 interaction type N/A PTMCode2
ITGB6 TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 APP 25361965 interaction type N/A PTMCode2
APP TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 LTBP3 25361965 interaction type N/A PTMCode2
LTBP3 TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 SDC2 25361965 interaction type N/A PTMCode2
SDC2 TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 BGN 25361965 interaction type N/A PTMCode2
BGN TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 MMP9 25361965 interaction type N/A PTMCode2
MMP9 TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 BMP2 25361965 interaction type N/A PTMCode2
BMP2 TGFB1 25361965 interaction type N/A PTMCode2
TGFBR3 TGFB1 25361965 interaction type N/A PTMCode2
TGFB1 TGFBR3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
VASN TGFB1 14525934 15247411 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DAXX TGFB1 24234451 25241761 25348397 physical association two hybrid,physical interaction,in vivo,proximity ligation assay ComPPI,IntAct
HOXA1 TGFB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CATSPER1 TGFB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP10-8 TGFB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP4-11 TGFB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AGR3 TGFB1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MEOX2 TGFB1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TGFB1 SPARC 14525934 15034927 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
TGFB1 CCL3 14525934 25348397 8568261 N/A experimental interaction detection,in vivo ComPPI,HPRD
TGFB1 THBS1 14525934 1550960 15864306 24234451 25348397 association experimental interaction detection,physical interaction,in vivo,solid phase assay ComPPI,HPRD,IntAct
TGFB1 TGFBR2 14525934 20856203 20860622 21054789 21441952 24234451 25348397 7935686 association,physical association anti tag coimmunoprecipitation,coimmunoprecipitation,cross-linking study,experimental interaction detection,surface plasmon resonance,physical interaction,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
TGFB1 TGFB2 25348397 N/A in vivo ComPPI
TGFB1 VTN 11796824 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TGFB1 ITGAV 11970960 14525934 21677751 24234451 25348397 physical association transmission electron microscopy,experimental interaction detection,molecular sieving,in vivo ComPPI,HPRD,IntAct
TGFB1 BGN 10383378 14525934 25348397 8093006 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TGFB1 FMOD 14525934 25348397 8093006 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TGFB1 TGFBR3 14525934 20856203 24234451 25348397 7935686 N/A coimmunoprecipitation,cross-linking study,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
TGFB1 FCN1 14525934 25348397 27898060 7686157 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
TGFB1 ACVRL1 10716993 14525934 25348397 N/A coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TGFB1 EIF3I 14525934 25348397 9813058 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
TGFB1 ITGB8 11970960 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
TGFB1 LTBP4 14525934 25348397 27898060 9660815 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
TGFB1 YWHAE 11172812 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
TGFB1 PZP 25348397 N/A physical interaction,in vitro ComPPI
TGFB1 BMP2 11456401 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TGFB1 BMP3 25348397 N/A in vivo ComPPI
TGFB1 DPT 14525934 25348397 9895299 N/A experimental interaction detection,in vitro ComPPI,HPRD
TGFB1 COL2A1 10085302 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TGFB1 MMP2 10652271 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
TGFB1 CCN2 10457363 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TGFB1 SDC2 14525934 14976204 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TGFB1 ENG 12015308 14525934 20856203 24234451 25348397 N/A cross-linking study,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
TGFB1 FNTA 14525934 25348397 8599089 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
TGFB1 ITGB6 10025398 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TGFB1 COL5A1 20979576 24234451 25348397 physical association two hybrid ComPPI,IntAct
TGFB1 MMP9 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
TGFB1 DCN 14525934 25348397 7638106 7798269 N/A experimental interaction detection,physical interaction ComPPI,HPRD
TGFB1 TGFBR1 14525934 20856203 24234451 25348397 8235612 N/A coimmunoprecipitation,cross-linking study,experimental interaction detection,physical interaction,biochemical ComPPI,HPRD,IntAct
TGFB1 LTBP1 12429738 24234451 25348397 colocalization transmission electron microscopy,light scattering,molecular sieving,pull down,physical interaction ComPPI,IntAct
TGFB1 LAMB1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TGFB1 EPS15 25348397 N/A physical interaction ComPPI
TGFB1 FBXO6 25348397 N/A physical interaction ComPPI
TGFB1 CCDC33 25348397 N/A physical interaction ComPPI
TGFB1 LAMTOR5 25348397 N/A physical interaction ComPPI
TGFB1 NMT1 25348397 N/A physical interaction ComPPI
TGFB1 NMT2 25348397 N/A physical interaction ComPPI
TGFB1 FEM1B 25348397 N/A physical interaction ComPPI
TGFB1 LAMC1 25348397 N/A physical interaction ComPPI
TGFB1 UBR1 25348397 N/A physical interaction ComPPI
TGFB1 RMND5A 25348397 N/A physical interaction ComPPI
TGFB1 EIF1AX 25348397 N/A physical interaction ComPPI
TGFB1 SLC35G2 25348397 N/A physical interaction ComPPI
TGFB1 ANGPTL4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 BCAS3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 BLID 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 CCL5 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 CST6 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 DIRAS3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 GREB1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 HOXC6 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 KLK5 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 KLK7 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 KLK9 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 MTA3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 PDLIM2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 PSMC3IP 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 SCGB3A1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 ST14 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 THRSP 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 PRSS50 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 NSD3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 APP 12867422 14525934 2119582 24234451 25241761 25348397 association,physical association protein cross-linking with a bifunctional reagent,experimental interaction detection,physical interaction,competition binding,proximity ligation assay ComPPI,HPRD,IntAct
TGFB1 ERP44 25348397 N/A physical interaction ComPPI
TGFB1 LRRC32 19651619 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TGFB1 DEFA1 25348397 N/A physical interaction ComPPI
TGFB1 NRROS 25348397 N/A physical interaction ComPPI
TGFB1 PLA2G10 25348397 N/A physical interaction ComPPI
TGFB1 TRIM25 25348397 N/A physical interaction ComPPI
TGFB1 FSTL1 20860622 24234451 25348397 physical association surface plasmon resonance,competition binding,surface plasmon resonance array ComPPI,IntAct
TGFB1 DIP2A 20860622 24234451 25348397 N/A surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
TGFB1 WFIKKN1 21054789 24234451 25348397 N/A surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
TGFB1 WFIKKN2 21054789 24234451 25348397 N/A surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
TGFB1 CILP 15864306 24234451 25348397 colocalization,association fluorescence microscopy,solid phase assay ComPPI,IntAct
TGFB1 APC 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFB1 AURKA 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFB1 AXIN2 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFB1 BMPR1A 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFB1 BUB1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFB1 CDKN2A 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFB1 DLC1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFB1 EGFR 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFB1 ERBB2 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFB1 FBXW7 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFB1 MCC 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFB1 MLH3 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFB1 PDGFRL 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFB1 TLR2 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFB1 LPXN 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGFB1 CYSRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGFB1 LCE3D 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGFB1 KRTAP1-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGFB1 LCE1C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGFB1 LCE1A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGFB1 LCE2B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGFB1 LCE3A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGFB1 LCE1D 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGFB1 LCE2C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGFB1 LCE3B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGFB1 POU4F2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGFB1 P4HB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGFB1 PSG1 24234451 25348397 25548275 N/A surface plasmon resonance,enzyme linked immunosorbent assay,surface plasmon resonance array ComPPI,IntAct
TGFB1 PSG9 24234451 25348397 27389696 N/A surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
FKBP1A TGFB1 25348397 N/A physical interaction ComPPI
SNAI1 TGFB1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BCL10 TGFB1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFB1 TGFB1 10930463 14525934 21677751 24234451 7935686 8617200 N/A transmission electron microscopy,experimental interaction detection,molecular sieving HPRD,IntAct
LTBP3 TGFB1 12062452 14525934 N/A experimental interaction detection HPRD
TGFB1 LRRC23 19651619 27898060 N/A N/A OmniPath
TGFB1 TGFBR2 10026191 11157754 11382746 12729750 12809600 1310899 15034927 18382895 20856203 20860622 21054789 21441952 26194464 27898060 7706250 7852346 7878020 7935686 8106553 8242742 9261125 stimulant N/A OmniPath
EGR1 TGFB1 12384981 27898060 stimulant N/A OmniPath
BRAF TGFB1 19861538 27898060 stimulant N/A OmniPath
MMP9 TGFB1 10652271 25241761 27898060 stimulant N/A OmniPath
TGFB1 PAX8 14623893 27898060 inhibition N/A OmniPath
TGFB1 PIK3R1 19114990 27898060 stimulant N/A OmniPath
MMP2 TGFB1 10652271 25241761 27898060 stimulant N/A OmniPath
TGFB1 NOS2 10362813 27898060 inhibition N/A OmniPath
TGFB1 TGFBR1 10187774 10716993 12809600 20856203 22326956 22703233 26194464 27898060 7706250 7852346 8235612 stimulant N/A OmniPath
TGFB1 RUNX2 11331591 27898060 inhibition N/A OmniPath
TDGF1 TGFB1 17030617 27898060 inhibition N/A OmniPath
ITGB6 TGFB1 10025398 20870411 27898060 stimulant N/A OmniPath
LTBP1 TGFB1 10930463 12429738 21677751 27898060 8432736 inhibition,stimulant N/A OmniPath
TGFB1 ACVRL1 10187774 10716993 18333754 27898060 8242742 N/A N/A OmniPath
TGFB1 PPP2R2A 19114990 27898060 stimulant N/A OmniPath
FBN1 TGFB1 17242066 27898060 stimulant N/A OmniPath

Visualization










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