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GENE：TNFRSF11B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TNFRSF11B
FullNmae TNF receptor superfamily member 11b
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11909
EnsembleID ENSG00000164761
Uniprot O00300

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TNFRSF11B immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TNFRSF11B autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TNFRSF11B autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TNFRSF11B GO:0001501,GO:0005125,GO:0005515,GO:0005576,GO:0005615,GO:0005886,GO:0006915,GO:0007165,GO:0007584,GO:0009410,GO:0030198,GO:0031012,GO:0032026,GO:0038023,GO:0042489,GO:0043235,GO:0043627,GO:0045671,GO:0045779,GO:0046685

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TNFRSF11B hsa:4982 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
TNFRSF11B hsa:4982 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA3 TNFRSF11B 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
RELA TNFRSF11B 18226221 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TNFRSF11B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TNFRSF11B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TNFRSF11B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CREB5 TNFRSF11B 21132541 trascriptional regulation,stimulation inferred by curator TFlink
HOXC8 TNFRSF11B 11139569 trascriptional regulation,stimulation inferred by curator TFlink
PPARG TNFRSF11B 12056809 trascriptional regulation,stimulation inferred by curator TFlink
SMAD1 TNFRSF11B 11139569 trascriptional regulation,stimulation inferred by curator TFlink
AR TNFRSF11B N/A trascriptional regulation,stimulation inferred by curator TFlink
ESR1 TNFRSF11B N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D TNFRSF11B 20371350 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
TNFSF10 TNFRSF11B 25361965 interaction type N/A PTMCode2
TNFRSF11B TNFSF10 25361965 interaction type N/A PTMCode2
TNFSF11 TNFRSF11B 25361965 interaction type N/A PTMCode2
TNFRSF11B TNFSF11 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
THBS1 TNFRSF11B 14525934 15799029 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
VTN TNFRSF11B 14525934 15799029 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TNFSF11 TNFRSF11B 12221720 14525934 22664871 24234451 25348397 9520411 N/A experimental interaction detection,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,in vivo ComPPI,HPRD,IntAct
VWF TNFRSF11B 14525934 15799029 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TNFRSF11A TNFRSF11B 23333834 24234451 25348397 physical association surface plasmon resonance,enzyme linked immunosorbent assay ComPPI,IntAct
TNFSF10 TNFRSF11B 12221720 14525934 25348397 9520411 N/A experimental interaction detection,in vitro ComPPI,HPRD
TNFRSF11B TNFSF13 10706119 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
TNFRSF11B FN1 14525934 15799029 N/A experimental interaction detection HPRD
TNFSF11 TNFRSF11B 11733492 12221720 27898060 9520411 9568710 stimulant N/A OmniPath

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