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GENE：AUP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AUP1
FullNmae AUP1 lipid droplet regulating VLDL assembly factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:891
EnsembleID ENSG00000115307
Uniprot Q9Y679

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AUP1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
AUP1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
AUP1 GO:0005515,GO:0005776,GO:0005783,GO:0005789,GO:0005811,GO:0009615,GO:0016020,GO:0016020,GO:0030433,GO:0030433,GO:0030970,GO:0031410,GO:0031624,GO:0031625,GO:0034389,GO:0043130,GO:0061724,GO:0070062,GO:0071712,GO:0140042,GO:1990044,GO:1990044

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 AUP1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF AUP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A AUP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 AUP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 AUP1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000070B1D AUP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE AUP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD AUP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 AUP1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
VCP AUP1 25348397 N/A physical interaction ComPPI
UBE2E3 AUP1 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
ABRAXAS2 AUP1 25348397 N/A physical interaction ComPPI
PTPRO AUP1 25348397 N/A physical interaction ComPPI
PRKDC AUP1 25348397 N/A physical interaction ComPPI
OPRK1 AUP1 23840749 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
OPRD1 AUP1 25348397 N/A physical interaction ComPPI
OPRM1 AUP1 23840749 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
ITGAV AUP1 25348397 N/A two hybrid,physical interaction ComPPI
TUBG1 AUP1 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
UBC AUP1 25348397 N/A physical interaction ComPPI
NTRK1 AUP1 25348397 N/A physical interaction ComPPI
CANX AUP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ILK AUP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ITGA2B AUP1 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
CFTR AUP1 25348397 N/A physical interaction ComPPI
SYVN1 AUP1 25348397 N/A physical interaction ComPPI
BRF2 AUP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ITGA1 AUP1 25348397 N/A two hybrid,physical interaction ComPPI
NDN AUP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MDC1 AUP1 25348397 N/A physical interaction ComPPI
AUP1 ITGA2 25348397 N/A two hybrid,physical interaction ComPPI
AUP1 ITGAM 25348397 N/A two hybrid,physical interaction ComPPI
AUP1 ITGA5 25348397 N/A two hybrid,physical interaction ComPPI
AUP1 ATG12 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
AUP1 KPTN 25348397 N/A physical interaction ComPPI
AUP1 CLN3 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AUP1 SEL1L 25348397 N/A anti tag coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,physical interaction ComPPI
AUP1 OS9 25348397 N/A physical interaction ComPPI
AUP1 FAF2 25348397 N/A physical interaction ComPPI
AUP1 RPN2 25348397 N/A physical interaction ComPPI
AUP1 DDOST 25348397 N/A physical interaction ComPPI
AUP1 SPTLC1 25348397 N/A physical interaction ComPPI
AUP1 LPCAT1 25348397 N/A physical interaction ComPPI
AUP1 STT3B 25348397 N/A physical interaction ComPPI
AUP1 UBE2J1 20435896 21857022 25348397 27898060 N/A physical interaction ComPPI,OmniPath
AUP1 KCND3 25348397 N/A physical interaction ComPPI
AUP1 AMFR 25348397 N/A physical interaction ComPPI
AUP1 HMGCR 25348397 N/A physical interaction ComPPI
AUP1 RNF139 25348397 N/A physical interaction ComPPI
AUP1 RNF11 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AUP1 FBXO6 25348397 N/A physical interaction ComPPI
AUP1 CAPRIN2 25348397 N/A physical interaction ComPPI
AUP1 SURF4 25348397 N/A physical interaction ComPPI
AUP1 CKAP5 25348397 N/A physical interaction ComPPI
AUP1 APOB 25348397 N/A physical interaction ComPPI
AUP1 PTP4A1 25348397 N/A physical interaction ComPPI
AUP1 RNF114 25348397 N/A physical interaction ComPPI
AUP1 FBXW11 25348397 N/A physical interaction ComPPI
AUP1 TUBA1C 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
AUP1 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
AUP1 STING1 24234451 25348397 29251827 association anti bait coimmunoprecipitation ComPPI,IntAct
CLN6 AUP1 24234451 30177828 association anti tag coimmunoprecipitation IntAct

Visualization










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