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GENE：TNFAIP3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TNFAIP3
FullNmae TNF alpha induced protein 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11896
EnsembleID ENSG00000118503
Uniprot P21580

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TNFAIP3 necroptosis 39827378 TNFAIP3-interacting protein 1 (TNIP1; also known as ABIN-1) is a ubiquitin-binding protein that suppresses death-receptor- or Toll-like receptor-mediated apoptosis and necroptosis; retulator signature
TNFAIP3 necroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
TNFAIP3 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TNFAIP3 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TNFAIP3 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TNFAIP3 GO:0001922,GO:0002020,GO:0002237,GO:0002634,GO:0002677,GO:0003677,GO:0004842,GO:0004843,GO:0004843,GO:0004843,GO:0004843,GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005764,GO:0005829,GO:0006915,GO:0006954,GO:0007010,GO:0008270,GO:0010803,GO:0016477,GO:0016579,GO:0019900,GO:0030177,GO:0031397,GO:0032088,GO:0032495,GO:0032691,GO:0032703,GO:0032715,GO:0032720,GO:0034136,GO:0034140,GO:0034144,GO:0034148,GO:0035523,GO:0035871,GO:0042802,GO:0043124,GO:0043130,GO:0043621,GO:0045732,GO:0045779,GO:0045824,GO:0048662,GO:0050691,GO:0050728,GO:0050869,GO:0061043,GO:0061578,GO:0061578,GO:0070062,GO:0070301,GO:0070423,GO:0070429,GO:0070433,GO:0070530,GO:0070536,GO:0070936,GO:0071108,GO:0071222,GO:0071947,GO:0072573,GO:0072666,GO:0090291,GO:1902042,GO:1990168,GO:2000347,GO:2000349,GO:2000352

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TNFAIP3 hsa:7128 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)
TNFAIP3 hsa:7128 path:hsa04217 Necroptosis - Homo sapiens (human)
TNFAIP3 hsa:7128 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
TNFAIP3 hsa:7128 path:hsa04657 IL-17 signaling pathway - Homo sapiens (human)
TNFAIP3 hsa:7128 path:hsa04668 TNF signaling pathway - Homo sapiens (human)
TNFAIP3 hsa:7128 path:hsa05162 Measles - Homo sapiens (human)
TNFAIP3 hsa:7128 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NFKB1 TNFAIP3 1332946 21725609 23178297 23572150 26192618 interaction type N/A ACSN
TNFAIP3 RIPK1 19131965 20599425 26192618 interaction type N/A ACSN
TNFAIP3 CUL3 20599425 26192618 interaction type N/A ACSN
TNFAIP3 RBX1 20599425 26192618 interaction type N/A ACSN
TRAF6 TNFAIP3 17703191 18239685 23180781 9928991 physical association anti tag coimmunoprecipitation InnateDB
TICAM1 TNFAIP3 15474016 23180781 physical association anti tag coimmunoprecipitation InnateDB
TNFAIP3 CHUK 11594795 23180781 physical association anti tag coimmunoprecipitation InnateDB
TBK1 TNFAIP3 15661910 23180781 physical association anti tag coimmunoprecipitation InnateDB
RELA TNFAIP3 12080044 16931600 17962196 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
DDX58 TNFAIP3 16306043 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK1 TNFAIP3 15258597 17703191 18246070 23180781 deubiquitination reaction,ubiquitination reaction,physical association anti tag coimmunoprecipitation,enzymatic study InnateDB
TNFAIP3 TNFAIP3 15258597 18164316 23180781 26467481 deubiquitination reaction,ubiquitination reaction,down-regulates activity enzymatic study InnateDB,Signor
CCDC50 TNFAIP3 18029035 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
YWHAB TNFAIP3 18029035 23180781 physical association two hybrid InnateDB
TNIP1 TNFAIP3 16684768 18029035 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
TNIP2 TNFAIP3 18029035 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
MALT1 TNFAIP3 18223652 23180781 cleavage reaction,physical association anti tag coimmunoprecipitation,protease assay InnateDB
TNFAIP3 USF1 17962196 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
SUPT5H TNFAIP3 17962196 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB TNFAIP3 17709380 23180781 phosphorylation reaction in-gel kinase assay InnateDB
TNFAIP3 TAX1BP1 18239685 23180781 physical association anti tag coimmunoprecipitation InnateDB
TNFAIP3 TRAF6 18239685 23180781 physical association anti tag coimmunoprecipitation InnateDB
TAX1BP1 TNFAIP3 18239685 18246070 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF7 TNFAIP3 20392859 23180781 physical association anti tag coimmunoprecipitation InnateDB
UBC TNFAIP3 19285159 23180781 physical association protein array InnateDB
IRAK1 TNFAIP3 21220427 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKE TNFAIP3 15661910 23180781 physical association anti tag coimmunoprecipitation InnateDB
KCNIP3 TNFAIP3 23180781 24487321 physical association anti tag coimmunoprecipitation InnateDB
USF1 TNFAIP3 23180781 24487321 physical association anti tag coimmunoprecipitation InnateDB
TRIM23 TNFAIP3 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
TICAM1 TNFAIP3 20005715 interaction type N/A PSP
TNIP2 TNFAIP3 20005715 interaction type N/A PSP
TRAF1 TNFAIP3 20005715 interaction type N/A PSP
TRAF2 TNFAIP3 20005715 interaction type N/A PSP
YWHAB TNFAIP3 20005715 interaction type N/A PSP
YWHAE TNFAIP3 20005715 interaction type N/A PSP
YWHAG TNFAIP3 20005715 interaction type N/A PSP
YWHAH TNFAIP3 20005715 interaction type N/A PSP
YWHAZ TNFAIP3 20005715 interaction type N/A PSP
TNIP2 TNFAIP3 10385526 11389905 11390377 18988627 20005715 20005715 N/A N/A SignaLink
YWHAB TNFAIP3 18988627 19615732 20005715 20005715 21071413 8702721 8702721 8702721 8702721 N/A N/A SignaLink
YWHAZ TNFAIP3 18988627 20005715 20005715 21071413 8702721 8702721 8702721 9299557 9299557 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR TNFAIP3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TNFAIP3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 TNFAIP3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TNFAIP3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 TNFAIP3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TNFAIP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TNFAIP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TNFAIP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TNFAIP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TNFAIP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TNFAIP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TNFAIP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TNFAIP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TNFAIP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TNFAIP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 TNFAIP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 TNFAIP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TNFAIP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 TNFAIP3 10807933 11880364 19343319 trascriptional regulation,stimulation inferred by curator TFlink
PML TNFAIP3 12080044 trascriptional regulation,stimulation inferred by curator TFlink
REL TNFAIP3 11880364 trascriptional regulation,stimulation inferred by curator TFlink
RELA TNFAIP3 10807933 11880364 19343319 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001F0C23 TNFAIP3 22550173 rna interference,inhibition western blot,quantitative reverse transcription pcr miRSponge
URS000009262D TNFAIP3 21131358 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000076995 TNFAIP3 21763284 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS000009262D TNFAIP3 21131358 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000076995 TNFAIP3 21763284 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00001F0C23 TNFAIP3 22550173 25416803 26758190 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000003ABC4 TNFAIP3 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000285DCB TNFAIP3 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000023133F TNFAIP3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 TNFAIP3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 TNFAIP3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 TNFAIP3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 TNFAIP3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000058BB84 TNFAIP3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC TNFAIP3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000321A1A TNFAIP3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000003E1A9 TNFAIP3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 TNFAIP3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000017EA6A TNFAIP3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C TNFAIP3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 TNFAIP3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 TNFAIP3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED TNFAIP3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002DD349 TNFAIP3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 TNFAIP3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 TNFAIP3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001383CF TNFAIP3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 TNFAIP3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 TNFAIP3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE TNFAIP3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 TNFAIP3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 TNFAIP3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000059EB31 TNFAIP3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 TNFAIP3 22473208 25416803 26367773 27991929 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000035CC3E TNFAIP3 25416803 26783726 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000000B1C9 TNFAIP3 25416803 26110642 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
TNFAIP3 RNF11 25361965 interaction type N/A PTMCode2
RNF11 TNFAIP3 25361965 interaction type N/A PTMCode2
TNFAIP3 YWHAH 25361965 interaction type N/A PTMCode2
YWHAH TNFAIP3 25361965 interaction type N/A PTMCode2
TNFAIP3 RIPK1 25361965 interaction type N/A PTMCode2
RIPK1 TNFAIP3 25361965 interaction type N/A PTMCode2
TNFAIP3 YWHAB 25361965 interaction type N/A PTMCode2
YWHAB TNFAIP3 25361965 interaction type N/A PTMCode2
TNFAIP3 TRAF6 25361965 interaction type N/A PTMCode2
TRAF6 TNFAIP3 25361965 interaction type N/A PTMCode2
TNFAIP3 TNIP2 25361965 interaction type N/A PTMCode2
TNIP2 TNFAIP3 25361965 interaction type N/A PTMCode2
TNFAIP3 TBK1 25361965 interaction type N/A PTMCode2
TBK1 TNFAIP3 25361965 interaction type N/A PTMCode2
TNFAIP3 CASP8 25361965 interaction type N/A PTMCode2
CASP8 TNFAIP3 25361965 interaction type N/A PTMCode2
TNFAIP3 IKBKG 25361965 interaction type N/A PTMCode2
IKBKG TNFAIP3 25361965 interaction type N/A PTMCode2
TNFAIP3 CHUK 25361965 interaction type N/A PTMCode2
CHUK TNFAIP3 25361965 interaction type N/A PTMCode2
TNFAIP3 TAX1BP1 25361965 interaction type N/A PTMCode2
TAX1BP1 TNFAIP3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ARRDC3 TNFAIP3 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TNFAIP3 TNIP1 10385526 11389905 12965196 14525934 21988832 24234451 25348397 25416956 30561431 association,physical association two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach,validated two hybrid,two hybrid,virotrap ComPPI,HPRD,IntAct
TNFAIP3 LAPTM5 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
TNFAIP3 CHUK 11594795 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TNFAIP3 YWHAZ 14525934 21988832 24234451 25348397 9299557 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
TNFAIP3 YWHAB 14525934 25348397 8702721 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
TNFAIP3 TRAF1 14525934 25348397 8692885 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
TNFAIP3 TRAF2 14525934 24234451 25348397 25416956 30561431 8692885 association,physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach,validated two hybrid,two hybrid,virotrap ComPPI,HPRD,IntAct
TNFAIP3 IKBKB 11594795 14525934 24234451 25348397 26649818 phosphorylation reaction experimental interaction detection,phosphorylation reaction,physical interaction,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
TNFAIP3 YWHAE 14525934 21988832 24234451 25348397 8702721 physical association two hybrid,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
TNFAIP3 TAX1BP1 10435631 11389905 14525934 24234451 25348397 30561431 association,physical association two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach,two hybrid,virotrap ComPPI,HPRD,IntAct
TNFAIP3 YWHAG 14525934 20936779 24234451 25348397 8702721 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vivo,two hybrid ComPPI,HPRD,IntAct
TNFAIP3 TNIP2 10385526 11389905 11390377 14525934 15169888 24234451 25348397 30561431 association,physical association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo,two hybrid,virotrap ComPPI,HPRD,IntAct
TNFAIP3 ZFAND5 14525934 14754897 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TNFAIP3 RIPK1 14525934 15258597 24234451 25348397 30561431 association experimental interaction detection,physical interaction,in vitro,in vivo,virotrap ComPPI,HPRD,IntAct
TNFAIP3 TICAM1 14525934 15474016 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
TNFAIP3 YWHAH 14525934 25348397 8702721 9299557 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
TNFAIP3 CCDC50 14525934 18029035 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TNFAIP3 RNF11 14525934 15231748 19131965 21765415 22507528 22975135 23018911 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
TNFAIP3 IKBKG 10755617 11389905 14525934 21988832 23032186 24234451 25348397 30561431 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid,virotrap ComPPI,HPRD,IntAct
TNFAIP3 CASP8 19060883 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TNFAIP3 LAMP1 25348397 N/A physical interaction ComPPI
TNFAIP3 ALDH9A1 25348397 N/A physical interaction ComPPI
TNFAIP3 GLDC 25348397 N/A physical interaction ComPPI
TNFAIP3 KIF11 25348397 N/A physical interaction ComPPI
TNFAIP3 MCM6 25348397 N/A physical interaction ComPPI
TNFAIP3 NDUFS1 25348397 N/A physical interaction ComPPI
TNFAIP3 PPP2R1B 25348397 N/A physical interaction ComPPI
TNFAIP3 CNKSR2 25348397 N/A physical interaction ComPPI
TNFAIP3 FBXO3 25348397 N/A physical interaction ComPPI
TNFAIP3 TBK1 24234451 25348397 30561431 association physical interaction,virotrap ComPPI,IntAct
TNFAIP3 PPP6R3 25348397 N/A physical interaction ComPPI
TNFAIP3 LRRC47 25348397 N/A physical interaction ComPPI
TNFAIP3 PLAAT4 25348397 N/A physical interaction ComPPI
TNFAIP3 BECN1 25348397 N/A physical interaction ComPPI
TNFAIP3 IRAK1 25348397 N/A physical interaction ComPPI
TNFAIP3 IRAK2 25348397 N/A physical interaction ComPPI
TNFAIP3 UBC 19373254 24234451 25348397 deubiquitination reaction nuclear magnetic resonance,physical interaction,enzymatic study,bio-layer interferometry,deubiquitinase assay ComPPI,IntAct
TNFAIP3 IRF7 25348397 N/A physical interaction ComPPI
TNFAIP3 TNF 23032186 24234451 25348397 30561431 association anti tag coimmunoprecipitation,physical interaction,virotrap ComPPI,IntAct
TNFAIP3 TNFRSF1A 24234451 25348397 30561431 association physical interaction,virotrap ComPPI,IntAct
TNFAIP3 FADD 24234451 25348397 30561431 association physical interaction,virotrap ComPPI,IntAct
TNFAIP3 MAP3K5 25348397 N/A physical interaction ComPPI
TNFAIP3 IKBKE 25348397 N/A physical interaction ComPPI
TNFAIP3 TNIP3 17088249 24234451 25348397 25416956 27898060 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct,OmniPath
TNFAIP3 RNF31 23032186 24234451 25348397 30561431 association anti tag coimmunoprecipitation,physical interaction,virotrap ComPPI,IntAct
TNFAIP3 SHARPIN 23032186 24234451 25348397 30561431 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,virotrap ComPPI,IntAct
TNFAIP3 RBCK1 23032186 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TNFAIP3 TNFSF10 25348397 N/A physical interaction ComPPI
TNFAIP3 TNFRSF10B 25348397 N/A physical interaction ComPPI
TNFAIP3 UBE2N 25348397 N/A physical interaction ComPPI
TNFAIP3 TRIM2 25348397 N/A physical interaction ComPPI
TNFAIP3 RNF5 25348397 N/A physical interaction ComPPI
TNFAIP3 RNF14 25348397 N/A physical interaction ComPPI
TNFAIP3 RLIM 25348397 N/A physical interaction ComPPI
TNFAIP3 TRIM3 25348397 N/A physical interaction ComPPI
TNFAIP3 TRIM8 25348397 N/A physical interaction ComPPI
TNFAIP3 TRIM5 25348397 N/A physical interaction ComPPI
TNFAIP3 HSP90AA1 25348397 N/A physical interaction ComPPI
TNFAIP3 HSP90AA2P 25348397 N/A physical interaction ComPPI
TNFAIP3 TP53 23471665 24099634 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TNFAIP3 AXIN1 25348397 N/A physical interaction ComPPI
TNFAIP3 GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNFAIP3 NFKB2 25348397 N/A physical interaction ComPPI
TNFAIP3 BIRC3 25348397 N/A physical interaction ComPPI
TNFAIP3 BIRC2 24234451 25348397 30561431 association physical interaction,virotrap ComPPI,IntAct
TNFAIP3 OCLN 22031828 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TNFAIP3 MALT1 25348397 N/A physical interaction ComPPI
TNFAIP3 ELAVL1 25348397 N/A physical interaction ComPPI
TNFAIP3 YWHAQ 25348397 N/A physical interaction ComPPI
TNFAIP3 RNF114 25348397 N/A physical interaction ComPPI
TNFAIP3 TRIM23 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TNFAIP3 NXF1 25348397 N/A physical interaction ComPPI
TNFAIP3 MTOR 25348397 26043155 27898060 N/A physical interaction ComPPI,OmniPath
TNFAIP3 NOD2 25348397 N/A physical interaction ComPPI
TNFAIP3 OTUD5 25348397 N/A physical interaction ComPPI
TNFAIP3 PCDHB5 25348397 N/A physical interaction ComPPI
TNFAIP3 RNF166 25348397 N/A physical interaction ComPPI
TNFAIP3 SHKBP1 25348397 N/A physical interaction ComPPI
TNFAIP3 UBB 25348397 N/A nuclear magnetic resonance,physical interaction,physical interaction,bio-layer interferometry,deubiquitinase assay ComPPI
TNFAIP3 ANKRD13D 25348397 N/A physical interaction ComPPI
TNFAIP3 TBC1D24 25348397 N/A physical interaction ComPPI
TNFAIP3 SRC 25348397 N/A physical interaction ComPPI
TNFAIP3 KCTD10 25348397 N/A physical interaction ComPPI
TNFAIP3 AIDA 25348397 N/A physical interaction ComPPI
TNFAIP3 NEDD4L 25348397 N/A physical interaction ComPPI
TNFAIP3 ARIH1 25348397 N/A physical interaction ComPPI
TNFAIP3 SNAI1 25348397 N/A physical interaction ComPPI
TNFAIP3 NFKB1 25348397 N/A physical interaction ComPPI
TNFAIP3 RPS27A 25348397 N/A nuclear magnetic resonance,physical interaction,bio-layer interferometry,deubiquitinase assay ComPPI
TNFAIP3 UBA52 25348397 N/A nuclear magnetic resonance,physical interaction,bio-layer interferometry,deubiquitinase assay ComPPI
TNFAIP3 KRR1 19131965 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNFAIP3 WNK1 20936779 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TNFAIP3 HSP90AB1 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
TNFAIP3 GAS8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFAIP3 LNX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFAIP3 RAD23A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFAIP3 RNF216 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRAF6 TNFAIP3 11463333 14525934 24234451 25348397 9928991 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
UBE2D1 TNFAIP3 25348397 N/A physical interaction ComPPI
RNH1 TNFAIP3 25348397 N/A physical interaction ComPPI
TNFAIP3 TNFAIP3 11389905 14525934 24234451 25416956 30561431 8692885 8797804 association,physical association coimmunoprecipitation,experimental interaction detection,two hybrid array,two hybrid prey pooling approach,two hybrid,virotrap HPRD,IntAct
TNFAIP3 HABP2 24234451 30561431 association virotrap IntAct
TNFAIP3 TTR 24234451 30561431 association virotrap IntAct
TNFAIP3 STAT1 24234451 30561431 association virotrap IntAct
TNFAIP3 RCC2 24234451 30561431 association virotrap IntAct
TNFAIP3 PREP 24234451 30561431 association virotrap IntAct
TNFAIP3 PCSK5 24234451 30561431 association virotrap IntAct
TNFAIP3 MYH11 24234451 30561431 association virotrap IntAct
TNFAIP3 G3BP1 24234451 30561431 association virotrap IntAct
TNFAIP3 CALCOCO2 24234451 30561431 association virotrap IntAct
TNFAIP3 DIPK2A 24234451 30561431 association virotrap IntAct
TNFAIP3 KIF5C 24234451 30561431 association virotrap IntAct
TNFAIP3 AZI2 24234451 30561431 association virotrap IntAct
TNFAIP3 ART4 24234451 30561431 association virotrap IntAct
TNFAIP3 PLEKHB2 24234451 30561431 association virotrap IntAct
TRADD TNFAIP3 24234451 30561431 association virotrap IntAct
TANK TNFAIP3 24234451 30561431 association virotrap IntAct
TNFAIP3 SEPSECS 24234451 30561431 association virotrap IntAct
TNFAIP3 SDK2 24234451 30561431 association virotrap IntAct
TNFAIP3 S1PR2 24234451 30561431 association virotrap IntAct
TNFAIP3 OPTN 24234451 30561431 association virotrap IntAct
TNFAIP3 LRRC69 24234451 30561431 association virotrap IntAct
TNFAIP3 GALNT1 24234451 30561431 association virotrap IntAct
TNFAIP3 AFM 24234451 30561431 association virotrap IntAct
TNFAIP3 SLC26A2 24234451 30561431 association virotrap IntAct
TNFAIP3 FZD7 24234451 30561431 association virotrap IntAct
UBC TNFAIP3 14748687 15334086 18029035 19285159 19373254 20622874 21095585 22099304 23032186 23032187 23827681 27898060 N/A N/A OmniPath
TNFAIP3 UBC 14748687 15334086 18029035 19285159 19373254 20622874 21095585 22099304 23032186 23032187 23827681 27898060 N/A N/A OmniPath
ITCH TNFAIP3 18246070 27898060 stimulant N/A OmniPath
CHUK TNFAIP3 11594795 27898060 N/A N/A OmniPath
TNFAIP3 CHUK 11594795 27898060 N/A N/A OmniPath
TICAM1 TNFAIP3 15474016 27898060 N/A N/A OmniPath
TNFAIP3 TNIP1 10385526 11389905 12586352 12965196 16684768 18029035 21988832 25165885 25416956 27898060 N/A N/A OmniPath
TNFAIP3 IKBKE 15661910 18353649 21885437 27898060 inhibition N/A OmniPath
IKBKE TNFAIP3 15661910 21885437 27898060 N/A N/A OmniPath
MALT1 TNFAIP3 18223652 27898060 N/A N/A OmniPath
TNFAIP3 TRAF6 11463333 15334086 17703191 18164316 18239685 20185725 20622874 21220427 21765415 23018911 23105109 23737552 27898060 9928991 inhibition N/A OmniPath
TRAF6 TNFAIP3 11463333 15334086 17703191 18164316 18239685 20185725 20622874 21220427 21765415 23018911 23105109 23737552 27898060 9928991 N/A N/A OmniPath
TNFAIP3 IKBKG 10755617 11389905 20932475 21988832 22099304 23032186 24859449 26802121 27898060 inhibition N/A OmniPath
TNFAIP3 TRADD 12654725 27898060 inhibition,stimulant N/A OmniPath
TNFAIP3 BECN1 20501938 27898060 inhibition N/A OmniPath
TNFAIP3 IRF7 20392859 27898060 N/A N/A OmniPath
TNFAIP3 DDX58 16306043 27898060 N/A N/A OmniPath
USF1 TNFAIP3 24487321 27898060 N/A N/A OmniPath
TNFAIP3 RIPK1 15258597 17703191 18239685 18246070 18570872 18621737 19131965 21765415 22585859 23602765 27898060 inhibition N/A OmniPath
RIPK1 TNFAIP3 15258597 17703191 18239685 18246070 18570872 18621737 19131965 21765415 22585859 23602765 27898060 N/A N/A OmniPath
TNFAIP3 TBK1 15661910 18353649 19615732 21885437 27898060 inhibition N/A OmniPath
IRAK1 TNFAIP3 21220427 27898060 N/A N/A OmniPath
IKBKB TNFAIP3 11594795 17709380 21220427 27898060 N/A N/A OmniPath
TNFAIP3 IKBKB 11594795 16684768 17709380 21220427 27898060 inhibition N/A OmniPath
TNFAIP3 TNIP2 10385526 11389905 11390377 15169888 18029035 21266526 27898060 N/A N/A OmniPath
TNFAIP3 CCDC50 18029035 27898060 N/A N/A OmniPath
CCDC50 TNFAIP3 18029035 27898060 N/A N/A OmniPath
TNFAIP3 TAX1BP1 10435631 11389905 18239685 18246070 20185725 21765415 23018911 27898060 N/A N/A OmniPath
TAX1BP1 TNFAIP3 10435631 11389905 18239685 18246070 20185725 21765415 23018911 27898060 stimulant N/A OmniPath
TNFAIP3 YWHAB 18029035 19615732 27898060 8702721 N/A N/A OmniPath
KCNIP3 TNFAIP3 24487321 27898060 N/A N/A OmniPath

Visualization










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