GENE：BOK
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | BOK |
| FullNmae | BCL2 family apoptosis regulator BOK |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:1087 |
| EnsembleID | ENSG00000176720 |
| Uniprot | Q9UMX3 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| BOK | parthanatos | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| BOK | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| BOK | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
| BOK | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| BOK | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| BOK | GO:0001836,GO:0005102,GO:0005515,GO:0005634,GO:0005640,GO:0005737,GO:0005739,GO:0005741,GO:0005743,GO:0005783,GO:0005789,GO:0005794,GO:0006915,GO:0006919,GO:0006921,GO:0008584,GO:0008630,GO:0008635,GO:0010506,GO:0031625,GO:0031901,GO:0031966,GO:0032588,GO:0033106,GO:0042803,GO:0042803,GO:0043065,GO:0043524,GO:0044877,GO:0046982,GO:0046982,GO:0048709,GO:0051259,GO:0051400,GO:0051402,GO:0051480,GO:0051902,GO:0055038,GO:0060546,GO:0072332,GO:0097192,GO:1900119,GO:1901029,GO:1901030,GO:1901382,GO:1902237,GO:1903899,GO:1904708,GO:2001244 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| BOK | hsa:666 | path:hsa04215 | Apoptosis - multiple species - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| YBX1 | BOK | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| EGR1 | BOK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | BOK | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |