Gene Information gene info

GENE:DEPDC5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DEPDC5
FullNmae DEP domain containing 5, GATOR1 subcomplex subunit
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18423
EnsembleID ENSG00000100150
Uniprot O75140

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DEPDC5 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DEPDC5 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
DEPDC5 GO:0005096,GO:0005096,GO:0005764,GO:0005765,GO:0005765,GO:0005765,GO:0005765,GO:0005765,GO:0005829,GO:0010508,GO:0031267,GO:0032007,GO:0034198,GO:0034198,GO:0034198,GO:0035556,GO:0044877,GO:0048471,GO:1904262,GO:1904262,GO:1904262,GO:1904262,GO:1990130,GO:1990130,GO:1990130

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DEPDC5 hsa:9681 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR DEPDC5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DEPDC5 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 DEPDC5 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 DEPDC5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DEPDC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DEPDC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DEPDC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DEPDC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DEPDC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DEPDC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DEPDC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DEPDC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DEPDC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 DEPDC5 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00001597DC DEPDC5 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
JUN DEPDC5 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
RRAGC DEPDC5 25348397 N/A anti tag coimmunoprecipitation,physical interaction,physical interaction ComPPI
RRAGB DEPDC5 25348397 N/A physical interaction ComPPI
RRAGA DEPDC5 25348397 N/A anti tag coimmunoprecipitation,physical interaction,physical interaction ComPPI
KPTN DEPDC5 25348397 N/A physical interaction ComPPI
NPRL2 DEPDC5 24234451 25263562 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2BC9 DEPDC5 24234451 30021884 physical association cross-linking study IntAct

Visualization