Gene Information gene info

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GENE：FBXO7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FBXO7
FullNmae F-box protein 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13586
EnsembleID ENSG00000100225
Uniprot Q9Y3I1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FBXO7 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FBXO7 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FBXO7 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FBXO7 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FBXO7 GO:0000151,GO:0000422,GO:0004842,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0005829,GO:0006511,GO:0006626,GO:0010975,GO:0016567,GO:0016567,GO:0016567,GO:0019005,GO:0019005,GO:0019901,GO:0019901,GO:0030098,GO:0031625,GO:0031647,GO:0032991,GO:0040012,GO:0043130,GO:0043161,GO:0045620,GO:0046982,GO:0097409,GO:0097414,GO:0097462,GO:1903377,GO:1903377,GO:1903599,GO:1903599,GO:1990037,GO:1990038,GO:1990756,GO:2000134

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FBXO7 BIRC2 16510124 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
FBXO7 SKP1 16278047 23180781 physical association anti tag coimmunoprecipitation InnateDB
FBXO7 CUL1 16278047 23180781 physical association anti tag coimmunoprecipitation InnateDB
CUL1 FBXO7 21145461 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR FBXO7 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 FBXO7 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 FBXO7 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 FBXO7 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 FBXO7 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 FBXO7 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 FBXO7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FBXO7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FBXO7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FBXO7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FBXO7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FBXO7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FBXO7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003380CC FBXO7 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS0000070B1D FBXO7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000007340 FBXO7 24374217 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK6 FBXO7 25348397 N/A physical interaction ComPPI
ZBTB48 FBXO7 25348397 N/A physical interaction ComPPI
SKP1 FBXO7 10531035 10531037 14525934 15145941 16278047 21378169 22632967 24234451 24947323 25348397 25416956 26496610 27705803 27898060 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,mammalian protein protein interaction trap,in vitro,in vivo,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct,OmniPath
PSMB2 FBXO7 25348397 N/A physical interaction ComPPI
COPS5 FBXO7 25348397 N/A physical interaction ComPPI
RBBP6 FBXO7 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2D2 FBXO7 25348397 N/A physical interaction ComPPI
PSMA3 FBXO7 24234451 25348397 25416956 25910212 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
BCAT1 FBXO7 25348397 N/A physical interaction ComPPI
RBX1 FBXO7 25348397 N/A physical interaction ComPPI
UBC FBXO7 25348397 N/A physical interaction ComPPI
PRMT1 FBXO7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NECTIN3 FBXO7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA6 FBXO7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB9 FBXO7 25348397 N/A physical interaction ComPPI
XPO1 FBXO7 25348397 N/A physical interaction ComPPI
TRAF2 FBXO7 22212761 25029497 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PSMC5 FBXO7 25348397 N/A physical interaction ComPPI
COPS2 FBXO7 25348397 N/A physical interaction ComPPI
CUL1 FBXO7 16278047 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC34 FBXO7 25348397 N/A physical interaction ComPPI
COPS3 FBXO7 25348397 N/A physical interaction ComPPI
SIRT1 FBXO7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS4 FBXO7 25348397 N/A physical interaction ComPPI
GPS1 FBXO7 25348397 N/A physical interaction ComPPI
COPS6 FBXO7 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS7A FBXO7 25348397 N/A physical interaction ComPPI
ELOC FBXO7 25348397 N/A physical interaction ComPPI
MAGED1 FBXO7 25348397 N/A physical interaction ComPPI
PRKN FBXO7 23933751 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
TSHR FBXO7 25348397 N/A physical interaction ComPPI
UBE2D3 FBXO7 25348397 N/A physical interaction ComPPI
YAF2 FBXO7 25348397 N/A physical interaction ComPPI
SEM1 FBXO7 24234451 24811749 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DUSP22 FBXO7 25348397 N/A physical interaction ComPPI
PSMB5 FBXO7 25348397 N/A physical interaction ComPPI
TRIM25 FBXO7 25348397 N/A physical interaction ComPPI
BIRC2 FBXO7 14525934 16510124 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
PSME3 FBXO7 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PSME1 FBXO7 25348397 N/A physical interaction ComPPI
PSME2 FBXO7 25348397 N/A physical interaction ComPPI
NSFL1C FBXO7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPOT FBXO7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXO7 ELF4 14525934 16581786 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FBXO7 DLGAP5 25348397 N/A physical interaction ComPPI
FBXO7 PINK1 23933751 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
FBXO7 SEC24C 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FBXO7 SEM1 25348397 N/A physical interaction ComPPI
FBXO7 PSMG2 25348397 N/A physical interaction ComPPI
FBXO7 PSMB7 25348397 N/A physical interaction ComPPI
FBXO7 RBFOX2 25348397 N/A physical interaction ComPPI
FBXO7 HSPD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXO7 PDE3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXO7 GBF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXO7 ESPL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXO7 HPSE 25348397 N/A physical interaction ComPPI
FBXO7 PANX1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXO7 FBXW2 25348397 N/A physical interaction ComPPI
FBXO7 CRNKL1 25348397 N/A physical interaction ComPPI
FBXO7 ESF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXO7 SRRT 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
FBXO7 PARP10 25348397 N/A physical interaction ComPPI
FBXO7 PSMA2 25348397 N/A physical interaction ComPPI
FBXO7 PSMB6 25348397 N/A physical interaction ComPPI
FBXO7 RNF181 25348397 N/A physical interaction ComPPI
FBXO7 COPS7B 25348397 N/A physical interaction ComPPI
FBXO7 AARSD1 25348397 N/A physical interaction ComPPI
FBXO7 C6ORF141 25348397 N/A physical interaction ComPPI
FBXO7 LOXL2 25348397 N/A physical interaction ComPPI
FBXO7 CCDC102B 25348397 N/A physical interaction ComPPI
FBXO7 TTC38 25348397 N/A physical interaction ComPPI
FBXO7 CELA3A 25348397 N/A physical interaction ComPPI
PSMB4 FBXO7 25348397 N/A physical interaction ComPPI
PSMB1 FBXO7 25348397 N/A physical interaction ComPPI
PSMB3 FBXO7 25348397 N/A physical interaction ComPPI
PSMF1 FBXO7 24234451 25348397 25416956 25910212 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
BIRC2 FBXO7 16510124 22212761 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009BF31A FBXO7 27087310 direct interaction,inhibition N/A NPInter

Visualization










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