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GENE：FOXK1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FOXK1
FullNmae forkhead box K1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23480
EnsembleID ENSG00000164916
Uniprot P85037

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FOXK1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FOXK1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FOXK1 GO:0000122,GO:0000785,GO:0000976,GO:0000978,GO:0000981,GO:0000981,GO:0001227,GO:0001678,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0006357,GO:0007517,GO:0010507,GO:0010906,GO:0030154,GO:0042594,GO:0045892,GO:0045893,GO:0061621,GO:0071889,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FOXK1 hsa:221937 path:hsa03083 Polycomb repressive complex - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FOXK1 BAP1 19615732 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF2 FOXK1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 FOXK1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 FOXK1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C FOXK1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 FOXK1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 FOXK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FOXK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FOXK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 FOXK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FOXK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FOXK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FOXK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 FOXK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FOXK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FOXK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FOXK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 FOXK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR FOXK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 FOXK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 FOXK1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000021D7C8 FOXK1 20371350 23824327 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS0000324096 FOXK1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00003D5391 FOXK1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D FOXK1 23622248 25416803 27292025 mrna cleavage,inhibition clip,clash TarBase
URS000041CB9C FOXK1 20371350 22473208 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS00004DA9DB FOXK1 23807165 25416803 mrna cleavage,inhibition array technology TarBase
URS0000171CD1 FOXK1 20371350 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D FOXK1 20371350 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A FOXK1 20371350 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000039A25B FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000038718E FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 FOXK1 20371350 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000118224 FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F FOXK1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001E3523 FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A FOXK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000004203C FOXK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000250A40 FOXK1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000010F787 FOXK1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 FOXK1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 FOXK1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 FOXK1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C FOXK1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 FOXK1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 FOXK1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 FOXK1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 FOXK1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 FOXK1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F FOXK1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA FOXK1 21572407 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 FOXK1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 FOXK1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 FOXK1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000007340 FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD231 FOXK1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 FOXK1 23313552 23824327 24906430 25416803 26701625 27292025 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS0000085F64 FOXK1 23313552 23824327 24906430 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS000075C3F6 FOXK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000AF45F FOXK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 FOXK1 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000BA274 FOXK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 FOXK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000171020 FOXK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000077DDE FOXK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E FOXK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 FOXK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005CE28 FOXK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEF5F FOXK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD FOXK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A92 FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000821E0 FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002373FD FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000096022 FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000003ABC4 FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003677B2 FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000033B548 FOXK1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000007FBA FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000006F90B FOXK1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00003ACE11 FOXK1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000BE495 FOXK1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000048BA36 FOXK1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000105D19 FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000EF0B FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001DC1D3 FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000038446A FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075AB0E FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000045ED38 FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000027F5F3 FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000759B6A FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005F1B8C FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000547F6A FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000047A8F FOXK1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001F373E FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000585553 FOXK1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000214763 FOXK1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00004F859B FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075ABF4 FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000049FAE8 FOXK1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000027464B FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000041FA2C FOXK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000C85B2 FOXK1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002152A8 FOXK1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AB32B FOXK1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075A760 FOXK1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 FOXK1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001496AE FOXK1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TFAP4 FOXK1 25348397 N/A physical interaction ComPPI
MAGOHB FOXK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VASP FOXK1 25348397 N/A physical interaction ComPPI
UBA7 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
VIM FOXK1 25348397 N/A physical interaction ComPPI
AMOT FOXK1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53BP1 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
RABGGTB FOXK1 25348397 N/A physical interaction ComPPI
BRMS1 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MAP1LC3B FOXK1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TEX264 FOXK1 25348397 N/A physical interaction ComPPI
NFATC1 FOXK1 25348397 N/A physical interaction ComPPI
RB1 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HCFC1 FOXK1 25348397 N/A physical interaction ComPPI
MAPK14 FOXK1 25348397 N/A physical interaction ComPPI
CTBP1 FOXK1 25348397 N/A physical interaction ComPPI
SRF FOXK1 25348397 N/A physical interaction ComPPI
NCOR1 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
YWHAB FOXK1 25348397 N/A physical interaction ComPPI
YWHAZ FOXK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PDGFRB FOXK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 FOXK1 25348397 N/A physical interaction ComPPI
PHKG2 FOXK1 25348397 N/A physical interaction ComPPI
RBL2 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SIN3A FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
POLD2 FOXK1 25348397 N/A physical interaction ComPPI
PSMA1 FOXK1 25348397 N/A physical interaction ComPPI
TNFRSF1A FOXK1 25348397 N/A physical interaction ComPPI
PRMT5 FOXK1 25348397 N/A physical interaction ComPPI
DYRK1B FOXK1 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NFATC2 FOXK1 25348397 N/A physical interaction ComPPI
PHKA2 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
XPO1 FOXK1 25348397 N/A physical interaction ComPPI
UBA2 FOXK1 25348397 N/A physical interaction ComPPI
DVL2 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NAA10 FOXK1 25348397 N/A physical interaction ComPPI
HDAC2 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CHEK2 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MAP1LC3A FOXK1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TP63 FOXK1 25348397 N/A physical interaction ComPPI
GPS2 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
AGTPBP1 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TRAK2 FOXK1 25348397 N/A physical interaction ComPPI
SAP30 FOXK1 24234451 25348397 25609649 26496610 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
IKZF1 FOXK1 25348397 N/A physical interaction ComPPI
EIF2AK3 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
UBE4B FOXK1 25348397 N/A physical interaction ComPPI
TBL1XR1 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXO3 FOXK1 24234451 25348397 25609649 association,physical association pull down,physical interaction,tandem affinity purification ComPPI,IntAct
DVL3 FOXK1 25348397 N/A physical interaction ComPPI
SUDS3 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
BRMS1L FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
BAP1 FOXK1 19615732 24234451 25348397 25609649 27705803 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
RNPS1 FOXK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBL1 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
DCAF7 FOXK1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
TBC1D4 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
EEF1D FOXK1 25348397 N/A physical interaction ComPPI
IRF2 FOXK1 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAX FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CMYA5 FOXK1 25348397 N/A physical interaction ComPPI
SCRIB FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
ARID4B FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SAP130 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
USP47 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
AGGF1 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
ING2 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
AP5Z1 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SINHCAF FOXK1 25348397 N/A physical interaction ComPPI
GAPVD1 FOXK1 25348397 N/A physical interaction ComPPI
KIAA0513 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
USP28 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MYCL FOXK1 25348397 N/A physical interaction ComPPI
UBR4 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
ASXL2 FOXK1 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
TP53 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TPM1 FOXK1 25348397 N/A physical interaction ComPPI
HDAC1 FOXK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBBP7 FOXK1 25348397 N/A physical interaction ComPPI
AHCY FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK1 FYCO1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FOXK1 METTL22 25348397 N/A physical interaction ComPPI
FOXK1 USP24 25348397 N/A physical interaction ComPPI
FOXK1 KLHDC3 25348397 N/A physical interaction ComPPI
FOXK1 ARID4A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK1 UHRF1BP1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK1 ANKRD52 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK1 KANK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK1 ANKRD28 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK1 ABHD10 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK1 PPP6R1 25348397 N/A physical interaction ComPPI
FOXK1 ASXL1 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK1 GATAD1 25348397 N/A physical interaction ComPPI
FOXK1 ZNF428 25348397 N/A physical interaction ComPPI
FOXK1 AHCYL2 25348397 N/A physical interaction ComPPI
FOXK1 TULP3 25348397 N/A physical interaction ComPPI
FOXK1 ZBTB39 25348397 N/A physical interaction ComPPI
NIBAN1 FOXK1 25348397 N/A physical interaction ComPPI
FOXK1 FOXK1 24234451 25609649 association tandem affinity purification IntAct

Visualization










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