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GENE：FOXK2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FOXK2
FullNmae forkhead box K2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6036
EnsembleID ENSG00000141568
Uniprot Q01167

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FOXK2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FOXK2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FOXK2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FOXK2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FOXK2 GO:0000122,GO:0000287,GO:0000785,GO:0000976,GO:0000978,GO:0000978,GO:0000981,GO:0000981,GO:0001227,GO:0001228,GO:0001678,GO:0003700,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005739,GO:0006355,GO:0006357,GO:0010507,GO:0010906,GO:0042594,GO:0043231,GO:0043565,GO:0045892,GO:0045893,GO:0045944,GO:0061621

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FOXK2 hsa:3607 path:hsa03083 Polycomb repressive complex - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL2 FOXK2 23180781 9065434 physical association electrophoretic mobility supershift assay,electrophoretic mobility shift assay InnateDB
IRF2 FOXK2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR FOXK2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 FOXK2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 FOXK2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 FOXK2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 FOXK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FOXK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FOXK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FOXK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FOXK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FOXK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FOXK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FOXK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FOXK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 FOXK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003380CC FOXK2 17612493 23592263 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS00004E008F FOXK2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000048BA36 FOXK2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E FOXK2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000345DEB FOXK2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA FOXK2 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F FOXK2 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 FOXK2 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 FOXK2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 FOXK2 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 FOXK2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 FOXK2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C FOXK2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 FOXK2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 FOXK2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 FOXK2 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000000E601 FOXK2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 FOXK2 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD FOXK2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000153377 FOXK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C FOXK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000F7766 FOXK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000029EBD FOXK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 FOXK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003E2232 FOXK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000031B6ED FOXK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 FOXK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB FOXK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA FOXK2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B FOXK2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000247AC6 FOXK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000057A7C FOXK2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000224AEA FOXK2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 FOXK2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002F0130 FOXK2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 FOXK2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000000C73C FOXK2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001CC379 FOXK2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001F9A0F FOXK2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000184017 FOXK2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 FOXK2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003E6EFA FOXK2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000072B4C8 FOXK2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 FOXK2 22135298 phosphorylation N/A PhosphoSite
CDK2 FOXK2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
KANSL1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HOXB9 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TFAP4 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FHL3 FOXK2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DPY30 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
AMOT FOXK2 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53BP1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
BRMS1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MAP1LC3B FOXK2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NHP2 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SF3A2 FOXK2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TBP FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NFATC1 FOXK2 25348397 N/A physical interaction ComPPI
RB1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HCFC1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HDAC3 FOXK2 25348397 N/A physical interaction ComPPI
SF3B1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
EIF5B FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HIRA FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NCOR2 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NCOR1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PDGFRB FOXK2 25348397 N/A physical interaction ComPPI
KMT2D FOXK2 25348397 N/A physical interaction ComPPI
SIN3A FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
ING1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TNFRSF1A FOXK2 25348397 N/A physical interaction ComPPI
TMF1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HNRNPL FOXK2 25348397 N/A physical interaction ComPPI
TPR FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
ZNF76 FOXK2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CTR9 FOXK2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPO1 FOXK2 25348397 N/A physical interaction ComPPI
RBBP5 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
RBBP4 FOXK2 25348397 N/A physical interaction ComPPI
KDM5A FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
DVL2 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SNX9 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SOX2 FOXK2 25348397 N/A physical interaction ComPPI
HDAC2 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MCRS1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NFYC FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
DRAP1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CHEK2 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
YTHDC1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MAP1LC3A FOXK2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TP63 FOXK2 25348397 N/A physical interaction ComPPI
MTA1 FOXK2 25348397 N/A physical interaction ComPPI
GPS2 FOXK2 25348397 N/A physical interaction ComPPI
MTA3 FOXK2 25348397 N/A physical interaction ComPPI
LIG3 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SMARCA1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PSIP1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CIC FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TBL1X FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PER1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
RNF4 FOXK2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SAP30 FOXK2 24234451 25348397 25609649 26496610 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
SIN3B FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
IKZF1 FOXK2 25348397 N/A physical interaction ComPPI
BARD1 FOXK2 25348397 N/A physical interaction ComPPI
GTF3C3 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
EMSY FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXE1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
RCOR1 FOXK2 25348397 N/A physical interaction ComPPI
TRIM25 FOXK2 25348397 N/A physical interaction ComPPI
EIF2AK3 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SRPK2 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TBL1XR1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NRF1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
BPTF FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
ESR1 FOXK2 25348397 N/A physical interaction ComPPI
DVL3 FOXK2 25348397 N/A physical interaction ComPPI
SUDS3 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
BRMS1L FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SNRNP200 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
DMAP1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
BAP1 FOXK2 19615732 24234451 25348397 25609649 27705803 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
TEAD2 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HECW2 FOXK2 25348397 N/A physical interaction ComPPI
PUF60 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SMARCA5 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MTA2 FOXK2 25348397 N/A physical interaction ComPPI
CDK11B FOXK2 25348397 N/A physical interaction ComPPI
MNT FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NUP107 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
IRF2 FOXK2 21903422 24234451 25348397 25609649 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
MAX FOXK2 24234451 25348397 25609649 association,physical association pull down,physical interaction,tandem affinity purification ComPPI,IntAct
THRAP3 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
KMT2B FOXK2 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
REST FOXK2 25348397 N/A physical interaction ComPPI
ARID4B FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SAP130 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
USP47 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SATB2 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MACROH2A1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CUX1 FOXK2 25348397 N/A physical interaction ComPPI
CDK11A FOXK2 25348397 N/A physical interaction ComPPI
ING2 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MAP1B FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
AP5Z1 FOXK2 25348397 N/A physical interaction ComPPI
SINHCAF FOXK2 25348397 N/A physical interaction ComPPI
HMGXB4 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
HOXD13 FOXK2 25348397 N/A physical interaction ComPPI
HOXC13 FOXK2 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
KANSL3 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PHF23 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
KIAA0513 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SAP30L FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
RSRC2 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
IL2 FOXK2 14525934 25348397 27898060 9065434 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
FOXK2 CBX6 25348397 N/A physical interaction ComPPI
FOXK2 RBBP7 25348397 N/A physical interaction ComPPI
FOXK2 SMU1 25348397 N/A physical interaction ComPPI
FOXK2 TEAD1 25348397 N/A physical interaction ComPPI
FOXK2 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 ARID4A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 ZBTB10 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 ASXL2 24234451 25348397 25609649 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 BAP18 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 ASXL1 24234451 25348397 25609649 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 CHD4 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 PRDM10 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 KDM1B 25348397 N/A physical interaction ComPPI
FOXK2 PHF20L1 25348397 N/A physical interaction ComPPI
FOXK2 CUX1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 TBL1Y 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 ADNP 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 KANSL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 UBR4 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 RBM26 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 ANKRD52 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 PRRC2C 25348397 N/A physical interaction ComPPI
FOXK2 UHRF1BP1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 ANKRD28 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 ABHD10 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 KANK2 24234451 25348397 25609649 association,physical association physical interaction,two hybrid array,tandem affinity purification,two hybrid prey pooling approach ComPPI,IntAct
FOXK2 FAM120A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 TP53 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXK2 HDAC1 25348397 N/A physical interaction ComPPI
FOXK2 ZNF428 25348397 N/A physical interaction ComPPI
FOXK2 AHCYL2 25348397 N/A physical interaction ComPPI
FOXK2 TULP3 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
FOXK2 ZBTB39 25348397 N/A physical interaction ComPPI
FOXK2 CPD 25348397 N/A physical interaction ComPPI
FOXK2 SETD1B 25348397 N/A physical interaction ComPPI
FOXK2 FOXK2 24234451 25609649 association tandem affinity purification IntAct
CDK2 FOXK2 20810654 27898060 stimulant N/A OmniPath
CDK1 FOXK2 20810654 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009ADAC4 FOXK2 27087310 direct interaction,inhibition N/A NPInter

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