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GENE：HTT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HTT
FullNmae huntingtin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4851
EnsembleID ENSG00000197386
Uniprot P42858

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HTT mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HTT autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HTT autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HTT autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
HTT apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HTT apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
HTT GO:0000132,GO:0002039,GO:0005515,GO:0005522,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005737,GO:0005769,GO:0005770,GO:0005776,GO:0005783,GO:0005794,GO:0005814,GO:0005829,GO:0006890,GO:0006915,GO:0007030,GO:0016234,GO:0019900,GO:0030424,GO:0030425,GO:0030659,GO:0031072,GO:0031587,GO:0031648,GO:0032991,GO:0032991,GO:0034452,GO:0042297,GO:0042802,GO:0043065,GO:0043666,GO:0044325,GO:0045505,GO:0045724,GO:0047496,GO:0048471,GO:0048471,GO:0048487,GO:0099111,GO:0099523,GO:0099524,GO:1903599,GO:1904504,GO:1905289,GO:1905337,GO:2000479,GO:2001237

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HTT hsa:3064 path:hsa05016 Huntington disease - Homo sapiens (human)
HTT hsa:3064 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
HTT AKT1 15843398 23180781 phosphorylation reaction protein kinase assay InnateDB
HTT ELP1 15383276 23180781 physical association two hybrid,pull down InnateDB
HTT WDFY3 20417604 23180781 physical association anti tag coimmunoprecipitation InnateDB
HTT CREB1 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
HTT TGM2 20005715 interaction type N/A PSP
HTT CASP1 20005715 interaction type N/A PSP
HTT AKT1 20005715 interaction type N/A PSP
HTT MAP3K10 10801775 20005715 21071413 interaction type N/A PSP,SignaLink
HTT PDK2 20005715 interaction type N/A PSP
HTT PIAS4 15383276 20005715 21071413 interaction type N/A PSP,SignaLink
HTT CREBBP 20005715 interaction type N/A PSP
HTT AKT1 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR HTT 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 HTT 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 HTT 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 HTT 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 HTT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HTT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HTT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HTT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HTT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 HTT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HTT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HTT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HTT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 HTT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 HTT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR HTT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 HTT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 HTT 22399227 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 HTT 22399227 trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A HTT 11483245 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 HTT 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00004505E4 HTT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D HTT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 HTT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA HTT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 HTT 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SGK1 HTT 22135298 phosphorylation N/A PhosphoSite
CDK5 HTT 22135298 phosphorylation N/A PhosphoSite
AKT1 HTT 22135298 phosphorylation N/A PhosphoSite
HIP1 HTT 25361965 interaction type N/A PTMCode2
HTT HIP1 25361965 interaction type N/A PTMCode2
HTT PRPF40B 25361965 interaction type N/A PTMCode2
PRPF40B HTT 25361965 interaction type N/A PTMCode2
HTT SETD2 25361965 interaction type N/A PTMCode2
SETD2 HTT 25361965 interaction type N/A PTMCode2
HTT SH3GL3 25361965 interaction type N/A PTMCode2
SH3GL3 HTT 25361965 interaction type N/A PTMCode2
HTT ZDHHC17 25361965 interaction type N/A PTMCode2
ZDHHC17 HTT 25361965 interaction type N/A PTMCode2
HTT AP2A2 25361965 interaction type N/A PTMCode2
AP2A2 HTT 25361965 interaction type N/A PTMCode2
DLG4 HTT 25361965 interaction type N/A PTMCode2
HTT DLG4 25361965 interaction type N/A PTMCode2
CBS HTT 25361965 interaction type N/A PTMCode2
HTT CBS 25361965 interaction type N/A PTMCode2
HAP1 HTT 25361965 interaction type N/A PTMCode2
HTT HAP1 25361965 interaction type N/A PTMCode2
TCERG1 HTT 25361965 interaction type N/A PTMCode2
HTT TCERG1 25361965 interaction type N/A PTMCode2
REST HTT 25361965 interaction type N/A PTMCode2
HTT REST 25361965 interaction type N/A PTMCode2
MAP3K10 HTT 25361965 interaction type N/A PTMCode2
HTT MAP3K10 25361965 interaction type N/A PTMCode2
CASP3 HTT 25361965 interaction type N/A PTMCode2
HTT CASP3 25361965 interaction type N/A PTMCode2
OPTN HTT 25361965 interaction type N/A PTMCode2
HTT OPTN 25361965 interaction type N/A PTMCode2
GRB2 HTT 25361965 interaction type N/A PTMCode2
HTT GRB2 25361965 interaction type N/A PTMCode2
HIP1R HTT 25361965 interaction type N/A PTMCode2
HTT HIP1R 25361965 interaction type N/A PTMCode2
HTT HTT 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PPL HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
PIK3R2 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
CUL5 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
ZMAT2 HTT 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping,two hybrid prey pooling approach ComPPI,IntAct
CHCHD2 HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
RNF40 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HNRNPC HTT 17500595 24234451 25348397 physical association pull down ComPPI,IntAct
NDUFB9 HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
KPNA3 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
FTL HTT 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping,two hybrid prey pooling approach ComPPI,IntAct
HSPA8 HTT 10942430 12417652 20026656 25348397 27898060 N/A physical interaction ComPPI,OmniPath
COX5B HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
SH3GLB1 HTT 12456676 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PAK2 HTT 19240112 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation ComPPI,IntAct,OmniPath
LDOC1 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
BAG3 HTT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HOXC4 HTT 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
H2AP HTT 14525934 23275563 24234451 25348397 9700202 physical association two hybrid,physical interaction,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
TUBB HTT 11870213 12417652 25348397 27898060 N/A physical interaction,in vitro,in vivo ComPPI,OmniPath
MRFAP1L1 HTT 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping,two hybrid prey pooling approach ComPPI,IntAct
TRAF6 HTT 25348397 N/A physical interaction ComPPI
VCP HTT 25348397 N/A physical interaction ComPPI
YWHAG HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
MED21 HTT 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
MRFAP1 HTT 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
OPTN HTT 11137014 14525934 17500595 23275563 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
MAGEB18 HTT 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
MAP1LC3B HTT 20417604 23303669 24234451 25348397 colocalization,association anti tag coimmunoprecipitation,confocal microscopy ComPPI,IntAct
COX5A HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
TSHZ3 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
PTGES2 HTT 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
RAC1 HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
DPPA4 HTT 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HSP90AB1 HTT 25348397 N/A physical interaction ComPPI
MAGEB6 HTT 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping,two hybrid prey pooling approach ComPPI,IntAct
HEYL HTT 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HEY2 HTT 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping,two hybrid prey pooling approach ComPPI,IntAct
UQCRH HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
GPRASP2 HTT 14525934 15383276 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
XAGE3 HTT 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping,two hybrid prey pooling approach ComPPI,IntAct
UBE2E3 HTT 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
PACSIN1 HTT 12354780 14525934 17161366 17500595 24234451 25348397 27898060 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
GGA2 HTT 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
DLG4 HTT 11319238 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
SP1 HTT 11839795 11988536 14525934 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
TBP HTT 10410676 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
PIK3R1 HTT 17500595 23275563 24234451 25348397 physical association two hybrid,physical interaction,two hybrid prey pooling approach ComPPI,IntAct
CD59 HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
CASP3 HTT 10770929 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAPK3 HTT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EVL HTT 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
GRB2 HTT 14525934 25348397 9079622 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CREBBP HTT 10823891 11264541 11607033 14525934 15994095 16456924 17500595 24234451 25348397 27898060 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
HMGA1 HTT 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
SUMO1 HTT 14525934 15064418 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
PIAS1 HTT 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
ZMYND8 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
OPRM1 HTT 25348397 N/A physical interaction ComPPI
CTBP1 HTT 11739372 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
KAT2B HTT 25348397 N/A physical interaction ComPPI
SORBS1 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
TGM2 HTT 11442349 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
SRGAP1 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
NBR1 HTT 20417604 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
FEZ1 HTT 14525934 15383276 17500595 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
MEOX1 HTT 23275563 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
SIAH1 HTT 25348397 N/A physical interaction ComPPI
SPART HTT 23275563 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
NCOR1 HTT 10441327 14525934 17500595 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
YWHAB HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
GAPDH HTT 14525934 17500595 24234451 25348397 27898060 8612237 physical association two hybrid,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct,OmniPath
PIK3R3 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
GIT1 HTT 14525934 15383276 24234451 25348397 colocalization,physical association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,imaging technique,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
ENO1 HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
AXIN1 HTT 25348397 N/A physical interaction ComPPI
PRNP HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
PRPF40A HTT 14525934 15383276 17161366 17500595 24234451 25348397 9700202 physical association two hybrid,experimental interaction detection,nuclear magnetic resonance,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
CASP1 HTT 14525934 25348397 9535906 N/A experimental interaction detection,in vitro ComPPI,HPRD
COPB1 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
CASP6 HTT 10770929 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
HAX1 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
PFN2 HTT 14525934 15383276 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid ComPPI,HPRD,IntAct
DNM1 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
STIP1 HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
CNTN1 HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
OPCML HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
LSAMP HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
MAP3K10 HTT 10801775 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SIN3A HTT 10823891 14525934 24234451 25348397 physical association experimental interaction detection,pull down,in vitro,in vivo ComPPI,HPRD,IntAct
MACO1 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
IKBKB HTT 25348397 N/A physical interaction ComPPI
SIRPA HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
DNAJA3 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HMG20A HTT 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping,two hybrid prey pooling approach ComPPI,IntAct
XRCC6 HTT 14525934 15383276 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
HNRNPL HTT 25348397 N/A physical interaction ComPPI
SREBF2 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
PPARG HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
KLF11 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
TPR HTT 15654337 25348397 27898060 N/A two hybrid,in vitro,in vivo ComPPI,OmniPath
SNAP25 HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
GPM6A HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
ADD3 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
STXBP1 HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
GRM1 HTT 25348397 N/A physical interaction ComPPI
HMGB1 HTT 23303669 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,confocal microscopy,proximity ligation assay ComPPI,IntAct
VDAC1 HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
PPP2CA HTT 25348397 N/A physical interaction ComPPI
PARD3 HTT 24234451 25348397 25942483 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PARD6A HTT 24234451 25348397 25942483 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SQSTM1 HTT 20417604 24234451 25348397 25686248 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
AP2A2 HTT 14525934 17500595 24234451 25348397 9700202 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PKM HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
BAZ1A HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBAC1 HTT 17500595 23275563 24234451 25348397 physical association two hybrid,physical interaction,two hybrid prey pooling approach ComPPI,IntAct
SYVN1 HTT 17141218 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SP3 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
PSMC5 HTT 18986984 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TRIP10 HTT 12604778 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
PRMT2 HTT 17500595 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ZBTB16 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
CLTC HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
RPS6KB1 HTT 25348397 N/A physical interaction ComPPI
HUWE1 HTT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBQLN2 HTT 25348397 N/A physical interaction ComPPI
VDAC2 HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
RPL4 HTT 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
CUL2 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
STX1A HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
WBP4 HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
EPB41L3 HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
ZDHHC17 HTT 12393793 14525934 15603740 23275563 24234451 24705354 25348397 27898060 9700202 palmitoylation reaction,physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,enzymatic study,in vitro,in vivo,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct,OmniPath
BCAP31 HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
STX1B HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
SYP HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
EGFR HTT 14525934 25348397 9079622 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TUBA1A HTT 25348397 N/A physical interaction ComPPI
RAB11A HTT 24234451 25348397 25942483 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RASA1 HTT 14525934 25348397 9079622 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
HTT PDK2 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HTT AKT1 12062094 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
HTT CBS 10434301 14525934 25348397 27898060 9466992 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD,OmniPath
HTT F8A1 11035034 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
HTT HAP1 10974549 15383276 25348397 27898060 7477378 9454836 9599014 9668110 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI,OmniPath
HTT HIP1 11063258 14525934 15383276 17500595 22835334 24234451 25348397 9147654 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
HTT CRMP1 14525934 15383276 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
HTT UBE2K 14525934 17500595 23275563 24234451 25348397 27898060 8702625 9700202 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct,OmniPath
HTT SH3GL3 14525934 15383276 16115810 17161366 24234451 25348397 27898060 9809064 physical association two hybrid,experimental interaction detection,nuclear magnetic resonance,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
HTT SAP30 10441327 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
HTT ELP1 14525934 15383276 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
HTT UTP14A 14525934 15383276 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
HTT PIAS4 14525934 15383276 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
HTT REST 12881722 25348397 27898060 N/A in vivo ComPPI,OmniPath
HTT SYMPK 14525934 25348397 9700202 N/A two hybrid,two hybrid ComPPI,HPRD
HTT TCERG1 11172033 14525934 15383276 17500595 24234451 25348397 27898060 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct,OmniPath
HTT SETD2 14525934 17500595 24234451 25348397 9700202 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
HTT PRPF40B 25348397 N/A two hybrid,physical interaction ComPPI
HTT TAF4 11988536 14525934 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
HTT MTSS1 14525934 15383276 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
HTT FICD 14525934 25348397 9700202 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
HTT HYPK 14525934 17500595 24234451 25348397 9700202 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
HTT MED31 14525934 15383276 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
HTT CEP126 15383276 24234451 25348397 physical association two hybrid,pull down ComPPI,IntAct
HTT NEUROD1 25348397 N/A physical interaction ComPPI
HTT MAGEA3 25348397 N/A physical interaction ComPPI
HTT TP53 10823891 14525934 24234451 25348397 physical association experimental interaction detection,pull down,physical interaction,biochemical ComPPI,HPRD,IntAct
HTT PACSIN2 25348397 N/A physical interaction ComPPI
HTT AGO2 18669659 20185826 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HTT AMFR 25348397 N/A physical interaction ComPPI
HTT CHUK 25348397 N/A physical interaction ComPPI
HTT UBQLN1 25348397 N/A physical interaction ComPPI
HTT IKBKG 25348397 N/A physical interaction ComPPI
HTT CTNNB1 17500595 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HTT CHD3 14525934 15383276 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid ComPPI,HPRD,IntAct
HTT DNAJB1 25348397 N/A physical interaction ComPPI
HTT DNAJA1 25348397 N/A physical interaction ComPPI
HTT HBS1L 25348397 N/A physical interaction ComPPI
HTT ATG5 20417604 24234451 25348397 colocalization,association anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
HTT MAP1LC3A 25348397 N/A physical interaction ComPPI
HTT ZNF451 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HTT ERCC6L 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping,two hybrid prey pooling approach ComPPI,IntAct
HTT TTC23 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HTT ZNF655 17500595 23275563 24234451 25348397 physical association two hybrid,physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HTT ZFYVE19 17500595 23275563 24234451 25348397 physical association two hybrid,physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HTT GOLPH3L 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping,two hybrid prey pooling approach ComPPI,IntAct
HTT DUSP10 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HTT ING5 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HTT IFT20 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HTT TACC1 17500595 23275563 24234451 25348397 physical association two hybrid,physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HTT MBD4 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HTT ETV4 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HTT PEX11B 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HTT MBD1 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping,two hybrid prey pooling approach ComPPI,IntAct
HTT TRAFD1 17500595 23275563 24234451 25348397 physical association two hybrid,physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HTT HOXC11 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HTT NUP58 17500595 23275563 24234451 25348397 physical association two hybrid,physical interaction,two hybrid prey pooling approach ComPPI,IntAct
HTT MIPEP 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
HTT PSMB7 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
HTT NME4 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
HTT ZFC3H1 25348397 N/A physical interaction ComPPI
HTT UPF3A 25348397 N/A physical interaction,luminescence based mammalian interactome mapping ComPPI
HTT CCDC126 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
HTT FAM71F1 25348397 N/A physical interaction ComPPI
HTT RCN2 25348397 N/A physical interaction ComPPI
HTT USP8 25348397 N/A physical interaction ComPPI
HTT MGRN1 25348397 N/A physical interaction ComPPI
HTT PML 25348397 N/A physical interaction ComPPI
HTT ITCH 24865853 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HTT USP14 25348397 N/A physical interaction ComPPI
HTT MID1 25348397 N/A physical interaction ComPPI
HTT CREB1 25348397 N/A physical interaction ComPPI
HTT HLA-B 25348397 N/A physical interaction ComPPI
HTT ULK1 24234451 25348397 25686248 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HTT RFXANK 25348397 N/A physical interaction ComPPI
HTT LLGL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HTT KIF23 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HTT RAPGEF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HTT MORC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HTT RAB30 25348397 N/A physical interaction ComPPI
HTT SNX21 25348397 N/A physical interaction ComPPI
HTT SYT12 25348397 N/A physical interaction ComPPI
HTT MPP1 25348397 N/A physical interaction ComPPI
HTT NPY2R 25348397 N/A physical interaction ComPPI
HTT CRYL1 25348397 N/A physical interaction ComPPI
HTT IL17RA 25348397 N/A physical interaction ComPPI
HTT C5AR2 25348397 N/A physical interaction ComPPI
HTT TKT 25348397 N/A physical interaction ComPPI
HTT RHEB 25348397 N/A physical interaction ComPPI
HTT MTOR 25348397 N/A physical interaction ComPPI
HTT DYNC1H1 17500595 17548833 24234451 25348397 association,physical association two hybrid,pull down,physical interaction ComPPI,IntAct
HTT ATG12 20417604 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
HTT ATG16L1 20417604 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
HTT WDFY3 20417604 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,confocal microscopy ComPPI,IntAct
HTT SNCA 22119730 24234451 25348397 27898060 colocalization,physical association comigration in non denaturing gel electrophoresis,fluorescence microscopy,bimolecular fluorescence complementation ComPPI,IntAct,OmniPath
HTT TM4SF19 23275563 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HTT PALM 23275563 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HTT ARFGAP3 23275563 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HTT FEM1B 23275563 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HTT DNAJC4 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT WAC 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT SRGAP2 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT PSMD4 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT MED15 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT CEP63 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT TOGARAM1 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT NAPB 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT EHMT1 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT MKRN2 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT ZNF675 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT USP9X 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT DNAJC21 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT MEF2D 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT APBB2 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT PIBF1 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT DCTN2 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT JAKMIP1 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT ZNF133 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT ARHGAP25 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT HSPD1 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT FNBP4 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT P4HA1 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT API5 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT GTF3C3 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT CCDC88A 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT SRGAP3 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT ODF2L 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT CHMP4B 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT TXNDC11 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT DNM2 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT DOCK11 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT SUPT5H 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT CLASP1 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT ZNF91 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT MRE11 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT NFKB1 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT TANK 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT DNAJC11 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT ARHGAP24 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT SASH1 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT DOCK9 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT PTK6 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT NUB1 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT BAIAP2 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT BZW2 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT PPA2 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT SRRT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT EZR 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT MTUS1 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT WDR91 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
HTT EPB41 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT CCT6A 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT DDB1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT PHB2 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT NDUFS3 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT CCT8 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT LDHAL6A 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT MT-CO2 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT PLP1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT SYT2 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT FBN2 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT NDUFS1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT TPP1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT LANCL1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT GNAO1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT GNB2 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT NTM 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT UQCRC2 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT CA4 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT SLC6A1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT NDUFA13 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT DIRAS2 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT CYC1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT THY1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT UQCRC1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT NDUFS5 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT NDUFB10 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT SLC25A12 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT COX6C 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT SEPTIN7 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT BASP1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT GFAP 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT VDAC3 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT NDUFA9 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT CNP 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT NEGR1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT COX6A1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT NDUFV1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT COX6B1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT GNB1 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT MT-CO3 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT NPTN 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT ASPH 17500595 24234451 25348397 physical association pull down ComPPI,IntAct
HTT SRP9 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT HSD17B10 17500595 24234451 25348397 association pull down ComPPI,IntAct
HTT AKAP8L 16391387 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
HTT BECN1 24234451 25348397 28445460 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
H3C1 HTT 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping,two hybrid prey pooling approach ComPPI,IntAct
ALDOC HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
OSTF1 HTT 17500595 23275563 24234451 25348397 physical association two hybrid,physical interaction,two hybrid prey pooling approach ComPPI,IntAct
EEF1D HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
GNAZ HTT 17500595 24234451 25348397 association pull down ComPPI,IntAct
ECH1 HTT 15383276 24234451 25348397 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
DNALI1 HTT 15383276 17500595 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RNF20 HTT 17500595 23275563 24234451 25348397 physical association two hybrid,physical interaction,two hybrid prey pooling approach ComPPI,IntAct
TUBB2A HTT 11870213 14525934 N/A experimental interaction detection HPRD
HIP1R HTT 11063258 14525934 N/A experimental interaction detection HPRD
HTT HTT 19487684 22119730 23275563 24234451 25848931 physical association anti tag coimmunoprecipitation,classical fluorescence spectroscopy,transmission electron microscopy,comigration in non denaturing gel electrophoresis,bimolecular fluorescence complementation,x-ray fiber diffraction,filter trap assay,two hybrid prey pooling approach IntAct
BDKRB1 HTT 24234451 28298427 physical association ubiquitin reconstruction IntAct
CDK5 HTT 15911879 17611284 18691976 19413330 24505464 25799558 27898060 stimulant N/A OmniPath
AKT1 HTT 12062094 14725621 15843398 16452687 16782707 18088087 18615096 18772195 19413330 19651622 20166139 24619418 24841383 27898060 N/A N/A OmniPath
HTT AKT1 12062094 15843398 27898060 N/A N/A OmniPath
TP53 HTT 10823891 18431400 27898060 stimulant N/A OmniPath
SGK1 HTT 14725621 27898060 inhibition N/A OmniPath
CSNK2A1 HTT 12062094 14725621 15843398 15911879 27898060 N/A N/A OmniPath

Visualization










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