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GENE：TNFRSF6B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TNFRSF6B
FullNmae TNF receptor superfamily member 6b
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11921
EnsembleID ENSG00000243509
Uniprot O95407

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TNFRSF6B necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TNFRSF6B GO:0005515,GO:0005576,GO:0005615,GO:0006915,GO:0038023,GO:0043066

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TNFRSF6B hsa:8771 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA1 TNFRSF6B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TNFRSF6B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
EGR1 TNFRSF6B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 TNFRSF6B \N rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000EED18 TNFRSF6B 17540599 25416803 mrna cleavage,inhibition array technology,northern blot TarBase

Source Target Pmid Interactiontype Methods Database
FASLG TNFRSF6B 25361965 interaction type N/A PTMCode2
TNFRSF6B FASLG 25361965 interaction type N/A PTMCode2
TNFRSF6B TNFSF15 25361965 interaction type N/A PTMCode2
TNFSF15 TNFRSF6B 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TNFRSF6B TNFSF15 25348397 N/A physical interaction,in vivo ComPPI
TNFRSF6B TNFSF14 10318773 24234451 25348397 physical association anti tag coimmunoprecipitation,fluorescence-activated cell sorting,physical interaction,in vivo ComPPI,IntAct
TNFRSF6B FASLG 21300286 24234451 25348397 N/A surface plasmon resonance,physical interaction,in vivo,surface plasmon resonance array ComPPI,IntAct
TNFRSF6B KRTAP10-9 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TNFRSF6B KRTAP10-3 25348397 N/A physical interaction ComPPI
TNFRSF6B PPP1R7 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
TNFSF14 TNFRSF6B 10318773 11390428 11994433 14697332 27898060 stimulant N/A OmniPath
TNFRSF6B FASLG 10318773 11994433 27898060 9872321 inhibition N/A OmniPath
FASLG TNFRSF6B 10318773 11994433 14697332 27898060 9872321 stimulant N/A OmniPath
TNFSF15 TNFRSF6B 11911831 14697332 27898060 stimulant N/A OmniPath
TNFRSF6B TNFSF15 11911831 27898060 inhibition N/A OmniPath

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