Gene Information gene info

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GENE：KLHL22

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KLHL22
FullNmae kelch like family member 22
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25888
EnsembleID ENSG00000099910
Uniprot Q53GT1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KLHL22 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KLHL22 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KLHL22 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
KLHL22 GO:0000070,GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005737,GO:0005764,GO:0005813,GO:0005827,GO:0005827,GO:0005829,GO:0005829,GO:0005829,GO:0006511,GO:0006513,GO:0006513,GO:0007094,GO:0010507,GO:0015630,GO:0030307,GO:0031463,GO:0031463,GO:0032480,GO:0043161,GO:0043161,GO:0043161,GO:0043231,GO:0045171,GO:0051301,GO:0071230,GO:0071233,GO:0071889,GO:0072686,GO:0072686,GO:1904263,GO:1904263,GO:1904263,GO:1990756

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CUL3 KLHL22 21145461 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 KLHL22 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
YBX1 KLHL22 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 KLHL22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA KLHL22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KLHL22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 KLHL22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 KLHL22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 KLHL22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS KLHL22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A KLHL22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF KLHL22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 KLHL22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 KLHL22 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 KLHL22 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 KLHL22 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
COPS6 KLHL22 25361965 interaction type N/A PTMCode2
KLHL22 COPS6 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NDUFB9 KLHL22 25348397 N/A physical interaction ComPPI
GMNN KLHL22 25348397 N/A physical interaction ComPPI
ATPAF2 KLHL22 25348397 N/A physical interaction ComPPI
NUDCD3 KLHL22 24234451 25036637 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
DCUN1D1 KLHL22 25348397 N/A physical interaction ComPPI
HSP90AB1 KLHL22 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
COPS5 KLHL22 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL3 KLHL22 25348397 N/A physical interaction ComPPI
HSP90AA1 KLHL22 25348397 N/A physical interaction ComPPI
NTRK1 KLHL22 25348397 N/A physical interaction ComPPI
FAF1 KLHL22 18775313 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBM14 KLHL22 25348397 N/A physical interaction ComPPI
PLK1 KLHL22 25348397 N/A physical interaction ComPPI
CFTR KLHL22 25348397 N/A physical interaction ComPPI
NEDD8 KLHL22 25348397 N/A physical interaction ComPPI
COPS6 KLHL22 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ZBTB33 KLHL22 25348397 N/A physical interaction ComPPI
CCL21 KLHL22 25348397 N/A physical interaction ComPPI
GFER KLHL22 25348397 N/A physical interaction ComPPI
BRCA1 KLHL22 25348397 N/A physical interaction ComPPI
GLUD1 KLHL22 25348397 N/A physical interaction ComPPI
SCARF2 KLHL22 25348397 N/A physical interaction ComPPI
NOB1 KLHL22 25348397 N/A physical interaction ComPPI
KLHL20 KLHL22 25348397 N/A physical interaction ComPPI
POLDIP3 KLHL22 25348397 N/A physical interaction ComPPI
CIZ1 KLHL22 25348397 N/A physical interaction ComPPI
UBXN1 KLHL22 18775313 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NOA1 KLHL22 25348397 N/A physical interaction ComPPI
GLUD2 KLHL22 25348397 N/A physical interaction ComPPI
KLHL26 KLHL22 25348397 N/A physical interaction ComPPI
TRMT6 KLHL22 25348397 N/A physical interaction ComPPI
MICU2 KLHL22 25348397 N/A physical interaction ComPPI
HSP90AA2P KLHL22 25348397 N/A physical interaction ComPPI
SCAF8 KLHL22 25348397 N/A physical interaction ComPPI
NIPSNAP2 KLHL22 25348397 N/A physical interaction ComPPI
KLHL13 KLHL22 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MICU1 KLHL22 25348397 N/A physical interaction ComPPI
KLHL9 KLHL22 25348397 N/A physical interaction ComPPI
KLHL22 UBXN7 18775313 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KLHL22 LYRM4 25348397 N/A physical interaction ComPPI
KLHL22 METTL15 25348397 N/A physical interaction ComPPI
KLHL22 ATG4C 25348397 N/A physical interaction ComPPI
KLHL22 NFS1 25348397 N/A physical interaction ComPPI
KLHL22 FMC1 25348397 N/A physical interaction ComPPI
KLHL22 NDUFAF5 25348397 N/A physical interaction ComPPI
KLHL22 TMEM223 25348397 N/A physical interaction ComPPI
KLHL22 LYRM7 25348397 N/A physical interaction ComPPI
KLHL22 RBM15B 25348397 N/A physical interaction ComPPI
KLHL22 ZBTB34 25348397 N/A physical interaction ComPPI
KLHL22 EMC7 25348397 N/A physical interaction ComPPI
KLHL22 ETFRF1 25348397 N/A physical interaction ComPPI
ADRA1A KLHL22 24234451 28298427 physical association ubiquitin reconstruction IntAct

Visualization










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