Gene Information gene info

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GENE：LGALS8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LGALS8
FullNmae galectin 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6569
EnsembleID ENSG00000116977
Uniprot O00214

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LGALS8 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LGALS8 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LGALS8 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LGALS8 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
LGALS8 GO:0005178,GO:0005178,GO:0005515,GO:0005615,GO:0005737,GO:0005737,GO:0005829,GO:0016020,GO:0030246,GO:0030246,GO:0031410,GO:0098586,GO:0098792,GO:1904977,GO:1904977

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
A2M LGALS8 18263896 23180781 physical association pull down InnateDB
ITIH4 LGALS8 18263896 23180781 physical association pull down InnateDB
HPX LGALS8 18263896 23180781 physical association pull down InnateDB
APOA1 LGALS8 18263896 23180781 physical association pull down InnateDB
ITGB1 LGALS8 16368432 18024965 18849583 19268462 23180781 physical association pull down InnateDB
ITGA3 LGALS8 16368432 18849583 23180781 physical association pull down InnateDB
ITGA5 LGALS8 16368432 18024965 18849583 23180781 physical association pull down InnateDB
ITGAV LGALS8 18849583 23180781 physical association pull down InnateDB
PDPN LGALS8 19268462 23180781 physical association pull down InnateDB
LGALS8 ITGA1 16368432 23180781 physical association pull down InnateDB
ITGA4 LGALS8 18024965 23180781 physical association pull down InnateDB
ITGAL LGALS8 18024965 23180781 physical association pull down InnateDB
LGALS9 LGALS8 17223646 23180781 physical association surface plasmon resonance InnateDB
MMP9 LGALS8 12881409 23180781 physical association pull down InnateDB
MMP3 LGALS8 12881409 23180781 physical association pull down InnateDB
APEH LGALS8 23180781 25416956 physical association two hybrid InnateDB
TRIM23 LGALS8 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR LGALS8 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 LGALS8 20034404 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 LGALS8 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 LGALS8 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 LGALS8 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 LGALS8 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A LGALS8 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
FOXA1 LGALS8 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 LGALS8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LGALS8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LGALS8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 LGALS8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LGALS8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LGALS8 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000204177 LGALS8 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS0000007340 LGALS8 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 LGALS8 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 LGALS8 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006B702 LGALS8 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000070B1D LGALS8 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 LGALS8 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS00000B7E30 LGALS8 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS00000AD002 LGALS8 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS000017EA6A LGALS8 25416803 28735896 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SPPL2A LGALS8 25348397 N/A physical interaction ComPPI
SLC1A1 LGALS8 25348397 N/A physical interaction ComPPI
ITGA7 LGALS8 25348397 N/A physical interaction ComPPI
TGIF1 LGALS8 18511908 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,fluorescence microscopy ComPPI,IntAct
ITGA3 LGALS8 25348397 N/A physical interaction,in vitro,in vivo ComPPI
ITGB1 LGALS8 25348397 N/A physical interaction,in vitro,in vivo ComPPI
NECTIN1 LGALS8 25348397 N/A physical interaction ComPPI
NECTIN3 LGALS8 25348397 N/A physical interaction ComPPI
C4A LGALS8 25348397 N/A physical interaction ComPPI
PTPRA LGALS8 25348397 N/A physical interaction ComPPI
PROCR LGALS8 25348397 N/A physical interaction ComPPI
PTPRG LGALS8 25348397 N/A physical interaction ComPPI
SLC4A2 LGALS8 25348397 N/A physical interaction ComPPI
CD47 LGALS8 25348397 N/A physical interaction ComPPI
SDCBP LGALS8 25348397 N/A physical interaction ComPPI
LNPEP LGALS8 25348397 N/A physical interaction ComPPI
TRIM23 LGALS8 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CUL1 LGALS8 25348397 N/A physical interaction ComPPI
DAG1 LGALS8 25348397 N/A physical interaction ComPPI
EGFR LGALS8 25348397 N/A physical interaction ComPPI
FGFR1 LGALS8 25348397 N/A physical interaction ComPPI
FLT4 LGALS8 25348397 N/A physical interaction ComPPI
ITGA1 LGALS8 25348397 N/A physical interaction ComPPI
ITGA6 LGALS8 25348397 N/A physical interaction ComPPI
SCARB2 LGALS8 25348397 N/A physical interaction ComPPI
TAX1BP1 LGALS8 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ITGA2 LGALS8 25348397 N/A physical interaction ComPPI
ITGA4 LGALS8 10852818 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
LGALS8 CALCOCO2 14525934 16189514 23386746 23511477 24234451 25348397 25416956 25771791 26186194 27898060 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct,OmniPath
LGALS8 NDP 25348397 N/A physical interaction ComPPI
LGALS8 BARD1 25348397 N/A physical interaction ComPPI
LGALS8 PAN2 25348397 N/A physical interaction ComPPI
LGALS8 MID2 25348397 N/A physical interaction ComPPI
LGALS8 COLEC12 25348397 N/A physical interaction ComPPI
LGALS8 PTPRK 25348397 N/A physical interaction ComPPI
LGALS8 RNF13 25348397 N/A physical interaction ComPPI
LGALS8 SV2A 25348397 N/A physical interaction ComPPI
LGALS8 ABCC4 25348397 N/A physical interaction ComPPI
LGALS8 KIAA0319L 25348397 N/A physical interaction ComPPI
LGALS8 ATP2B4 25348397 N/A physical interaction ComPPI
LGALS8 ATP2B2 25348397 N/A physical interaction ComPPI
LGALS8 ATP2B3 25348397 N/A physical interaction ComPPI
LGALS8 SLC30A1 25348397 N/A physical interaction ComPPI
LGALS8 SLC9A6 25348397 N/A physical interaction ComPPI
LGALS8 RRAGC 25348397 N/A physical interaction ComPPI
LGALS8 SLC12A9 25348397 N/A physical interaction ComPPI
LGALS8 SLC12A2 25348397 N/A physical interaction ComPPI
LGALS8 ITGA5 25348397 N/A physical interaction ComPPI
LGALS8 MFAP3 25348397 N/A physical interaction ComPPI
LGALS8 KIAA1549 25348397 N/A physical interaction ComPPI
LGALS8 ALCAM 25348397 N/A physical interaction ComPPI
LGALS8 ATP6V0A2 25348397 N/A physical interaction ComPPI
LGALS8 ATP6V0A1 25348397 N/A physical interaction ComPPI
LGALS8 C1ORF159 25348397 N/A physical interaction ComPPI
LGALS8 NCR3LG1 25348397 N/A physical interaction ComPPI
LGALS8 PODXL 25348397 N/A physical interaction ComPPI
LGALS8 PTPRJ 25348397 N/A physical interaction ComPPI
LGALS8 FN1 25348397 N/A physical interaction ComPPI
LGALS8 EMB 25348397 N/A physical interaction ComPPI
LGALS8 CD58 25348397 N/A physical interaction ComPPI
LGALS8 SLC12A6 25348397 N/A physical interaction ComPPI
LGALS8 SLC12A4 25348397 N/A physical interaction ComPPI
LGALS8 SLC12A7 25348397 N/A physical interaction ComPPI
LGALS8 CSPG4 25348397 N/A physical interaction ComPPI
LGALS8 NPC1 25348397 N/A physical interaction ComPPI
LGALS8 ACP2 25348397 N/A physical interaction ComPPI
LGALS8 GLMP 25348397 N/A physical interaction ComPPI
LGALS8 ADCY6 25348397 N/A physical interaction ComPPI
LGALS8 PTGFRN 25348397 N/A physical interaction ComPPI
LGALS8 ADCY9 25348397 N/A physical interaction ComPPI
LGALS8 SLC22A23 25348397 N/A physical interaction ComPPI
LGALS8 SLC4A7 25348397 N/A physical interaction ComPPI
LGALS8 CLCN5 25348397 N/A physical interaction ComPPI
LGALS8 CLCN3 25348397 N/A physical interaction ComPPI
LGALS8 ENPP4 25348397 N/A physical interaction ComPPI
LGALS8 LRRC8E 25348397 N/A physical interaction ComPPI
LGALS8 LRRC8A 25348397 N/A physical interaction ComPPI
LGALS8 LRRC8C 25348397 N/A physical interaction ComPPI
LGALS8 TMEM237 25348397 N/A physical interaction ComPPI
LGALS8 SORL1 25348397 N/A physical interaction ComPPI
LGALS8 SLC35A5 25348397 N/A physical interaction ComPPI
LGALS8 SLC17A5 25348397 N/A physical interaction ComPPI
LGALS8 MRC2 25348397 N/A physical interaction ComPPI
LGALS8 ANO6 25348397 N/A physical interaction ComPPI
LGALS8 ATP13A3 25348397 N/A physical interaction ComPPI
LGALS8 SLC36A1 25348397 N/A physical interaction ComPPI
LGALS8 SUSD5 25348397 N/A physical interaction ComPPI
LGALS8 HEG1 25348397 N/A physical interaction ComPPI
LGALS8 TMEM63B 25348397 N/A physical interaction ComPPI
LGALS8 SLC26A2 25348397 N/A physical interaction ComPPI
LGALS8 RRAGB 25348397 N/A physical interaction ComPPI
LGALS8 SLC38A9 25348397 N/A physical interaction ComPPI
LGALS8 CD276 25348397 N/A physical interaction ComPPI
LGALS8 CLCN7 25348397 N/A physical interaction ComPPI
LGALS8 LAMA4 25348397 N/A physical interaction ComPPI
LGALS8 ATG9A 25348397 N/A physical interaction ComPPI
LGALS8 OSTM1 25348397 N/A physical interaction ComPPI
LGALS8 TRPM4 25348397 N/A physical interaction ComPPI
LGALS8 SDK1 25348397 N/A physical interaction ComPPI
LGALS8 CD63 25348397 N/A physical interaction ComPPI
LGALS8 MCAM 25348397 N/A physical interaction ComPPI
LGALS8 SEZ6L2 25348397 N/A physical interaction ComPPI
LGALS8 TMEM63A 25348397 N/A physical interaction ComPPI
LGALS8 SLC31A1 25348397 N/A physical interaction ComPPI
LGALS8 LRRC4B 25348397 N/A physical interaction ComPPI
LGALS8 ECE1 25348397 N/A physical interaction ComPPI
LGALS8 ABCC1 25348397 N/A physical interaction ComPPI
LGALS8 TRIM5 25348397 N/A physical interaction ComPPI
LGALS8 TRIM6 25348397 N/A physical interaction ComPPI
LGALS8 TRIM17 25348397 N/A physical interaction ComPPI
LGALS8 MEFV 25348397 N/A physical interaction ComPPI
LGALS8 TRIM22 25348397 N/A physical interaction ComPPI
LGALS8 TRIM49 25348397 N/A physical interaction ComPPI
LGALS8 LRRK2 24234451 24510904 25348397 N/A protein array ComPPI,IntAct
APEH LGALS8 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LGALS8 LGALS8 22913484 24234451 N/A x-ray crystallography IntAct

Visualization










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