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GENE：MFSD8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MFSD8
FullNmae major facilitator superfamily domain containing 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28486
EnsembleID ENSG00000164073
Uniprot Q8NHS3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MFSD8 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
MFSD8 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
MFSD8 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MFSD8 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
MFSD8 GO:0005254,GO:0005765,GO:0005765,GO:0007040,GO:0010008,GO:0010506,GO:0015111,GO:0015705,GO:0038202,GO:0048666,GO:0062054,GO:0097352,GO:1902476,GO:1903424,GO:1905165

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MFSD8 hsa:256471 path:hsa04142 Lysosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FOXP3 MFSD8 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MFSD8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MFSD8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 MFSD8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MFSD8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MFSD8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MFSD8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MFSD8 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000171525 MFSD8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003758F0 MFSD8 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001F5B39 MFSD8 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002C7B2B MFSD8 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000EED18 MFSD8 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003E6EFA MFSD8 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002198F3 MFSD8 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D MFSD8 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 MFSD8 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C MFSD8 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 MFSD8 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001A122A MFSD8 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 MFSD8 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000032EF64 MFSD8 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000237CBD MFSD8 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D MFSD8 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000000B1C9 MFSD8 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000A07C1 MFSD8 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 MFSD8 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 MFSD8 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB MFSD8 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA MFSD8 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA MFSD8 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 MFSD8 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 MFSD8 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 MFSD8 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F MFSD8 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA MFSD8 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 MFSD8 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 MFSD8 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
YIPF3 MFSD8 25348397 N/A physical interaction ComPPI
PTGIR MFSD8 25348397 N/A physical interaction ComPPI
EBP MFSD8 25348397 N/A physical interaction ComPPI
PTPRN MFSD8 25348397 N/A physical interaction ComPPI
HLA-DQA1 MFSD8 25348397 N/A physical interaction ComPPI
C3AR1 MFSD8 25348397 N/A physical interaction ComPPI
FPR2 MFSD8 25348397 N/A physical interaction ComPPI
LPAR1 MFSD8 25348397 N/A physical interaction ComPPI
P2RY12 MFSD8 25348397 N/A physical interaction ComPPI
EPHX1 MFSD8 25348397 N/A physical interaction ComPPI

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