Gene Information gene info

  1. Home

GENE：NPRL2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NPRL2
FullNmae NPR2 like, GATOR1 complex subunit
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24969
EnsembleID ENSG00000114388
Uniprot Q8WTW4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NPRL2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NPRL2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NPRL2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
NPRL2 GO:0005096,GO:0005096,GO:0005515,GO:0005765,GO:0005765,GO:0005765,GO:0005774,GO:0010508,GO:0032007,GO:0033673,GO:0034198,GO:0034198,GO:0034198,GO:1904262,GO:1904262,GO:1904262,GO:1990130,GO:1990130,GO:1990130

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NPRL2 hsa:10641 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NPRL2 PDK1 18616680 23180781 physical association anti tag coimmunoprecipitation InnateDB
NPRL2 SRC 18616680 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 NPRL2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 NPRL2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
VDR NPRL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC NPRL2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 NPRL2 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
CDKN1A NPRL2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
APPBP2 NPRL2 25348397 N/A physical interaction ComPPI
ZBTB5 NPRL2 25348397 N/A physical interaction ComPPI
PRKAR1A NPRL2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HSP90AA1 NPRL2 25348397 N/A physical interaction ComPPI
UBE2M NPRL2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RRAGA NPRL2 25348397 N/A physical interaction ComPPI
SESN2 NPRL2 24234451 25348397 28199315 association anti bait coimmunoprecipitation ComPPI,IntAct
ZNF414 NPRL2 25348397 N/A physical interaction ComPPI
WDR24 NPRL2 24234451 25348397 28199315 colocalization,association cosedimentation through density gradient,cross-linking study,molecular sieving,physical interaction ComPPI,IntAct
LAMP1 NPRL2 24234451 25348397 28199315 colocalization cosedimentation through density gradient ComPPI,IntAct
HERC2 NPRL2 25348397 N/A physical interaction ComPPI
NXF1 NPRL2 25348397 N/A physical interaction ComPPI
HERC2P3 NPRL2 25348397 N/A physical interaction ComPPI
NPRL2 NPRL3 19521502 24234451 25348397 28199315 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cosedimentation through density gradient,molecular sieving,physical interaction ComPPI,IntAct
NPRL2 ANXA7 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NPRL2 HSP90AA2P 25348397 N/A physical interaction ComPPI
NPRL2 MOV10 25348397 N/A physical interaction ComPPI
NPRL2 DEPDC5 24234451 25263562 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NPRL2 WDR59 24234451 25348397 28199315 colocalization,association cosedimentation through density gradient,molecular sieving,physical interaction ComPPI,IntAct
NPRL2 SEH1L 25348397 N/A physical interaction ComPPI
NPRL2 BMT2 25348397 N/A physical interaction ComPPI
NPRL2 LRCH2 25348397 N/A physical interaction ComPPI
NPRL2 SZT2 24234451 25348397 28199315 colocalization,association anti tag coimmunoprecipitation,cosedimentation through density gradient,molecular sieving ComPPI,IntAct
NPRL2 MIOS 24234451 25348397 28199315 association molecular sieving ComPPI,IntAct

Visualization










  Return