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GENE：POLDIP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol POLDIP2
FullNmae DNA polymerase delta interacting protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23781
EnsembleID ENSG00000004142
Uniprot Q9Y2S7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
POLDIP2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
POLDIP2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
POLDIP2 GO:0003677,GO:0005515,GO:0005634,GO:0005634,GO:0005739,GO:0005759,GO:0005911,GO:0016242,GO:0030496,GO:0042645,GO:0042645,GO:0045931,GO:0051894,GO:0070584,GO:0070987,GO:0070987,GO:0072686,GO:0090307,GO:1903490,GO:1990874

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ALAS1 POLDIP2 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 POLDIP2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC POLDIP2 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
CTCF POLDIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 POLDIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003ACE11 POLDIP2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000057FDB8 POLDIP2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 POLDIP2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 POLDIP2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000032BDF4 POLDIP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000096022 POLDIP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000BA274 POLDIP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002ED720 POLDIP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000036B845 POLDIP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA POLDIP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000521626 POLDIP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF POLDIP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004F859B POLDIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CHCHD2 POLDIP2 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAD2L2 POLDIP2 25348397 N/A physical interaction ComPPI
BOLA1 POLDIP2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
PCNA POLDIP2 12522211 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
POLDIP2 POLD2 25348397 N/A two hybrid,in vitro,in vivo ComPPI
POLDIP2 CPE 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
POLDIP2 SELENBP1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
POLDIP2 ASCC2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
POLDIP2 REV1 25348397 N/A physical interaction ComPPI
POLDIP2 MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLDIP2 PDPK1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
POLDIP2 HDAC6 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
POLDIP2 TAB1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
POLDIP2 CUL3 25348397 N/A physical interaction ComPPI
POLDIP2 APP 25348397 N/A physical interaction ComPPI
POLDIP2 PPP2R1A 25348397 N/A physical interaction ComPPI
POLDIP2 TP53 25348397 N/A physical interaction ComPPI
POLDIP2 ALAS1 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
POLDIP2 MTUS2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
POLDIP2 SHMT2 25348397 N/A physical interaction ComPPI
POLDIP2 MOV10 25348397 N/A physical interaction ComPPI
POLDIP2 NXF1 25348397 N/A physical interaction ComPPI
POLDIP2 EGFR 25348397 N/A physical interaction ComPPI
POLDIP2 PTEN 25348397 N/A physical interaction ComPPI
POLDIP2 MED23 25348397 N/A physical interaction ComPPI
POLDIP2 MCM2 25348397 N/A physical interaction ComPPI
POLDIP2 CHCHD10 25348397 N/A physical interaction ComPPI
POLDIP2 CISD3 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLDIP2 FMC1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLDIP2 SPATA20 25348397 N/A physical interaction ComPPI
POLDIP2 NDUFA4 25348397 N/A physical interaction ComPPI
POLDIP2 PTPMT1 25348397 N/A physical interaction ComPPI
POLDIP2 NME4 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLDIP2 COQ9 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLDIP2 COQ6 25348397 N/A physical interaction ComPPI
POLDIP2 XPNPEP3 25348397 N/A physical interaction ComPPI
POLDIP2 NDUFAF8 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLDIP2 TRUB2 25348397 N/A physical interaction ComPPI
POLDIP2 NDUFS3 25348397 N/A physical interaction ComPPI
POLDIP2 MTRES1 25348397 N/A physical interaction ComPPI
POLDIP2 COQ5 25348397 N/A physical interaction ComPPI
POLDIP2 DHRS4 25348397 N/A physical interaction ComPPI
POLDIP2 NMES1 25348397 N/A physical interaction ComPPI
POLDIP2 LACTB 25348397 N/A physical interaction ComPPI
POLDIP2 ATP5F1A 25348397 N/A physical interaction ComPPI
POLDIP2 COQ7 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLDIP2 COQ8B 25348397 N/A physical interaction ComPPI
POLDIP2 LYRM2 25348397 N/A physical interaction ComPPI
POLDIP2 COQ10B 25348397 N/A physical interaction ComPPI
POLDIP2 PAK5 25348397 N/A physical interaction ComPPI
POLDIP2 FAM136A 25348397 N/A physical interaction ComPPI
POLDIP2 COQ4 25348397 N/A physical interaction ComPPI
POLDIP2 COQ8A 25348397 N/A physical interaction ComPPI
POLDIP2 NIT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLDIP2 SUGCT 25348397 N/A physical interaction ComPPI
POLDIP2 OCIAD1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLDIP2 NDUFAF4 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLDIP2 HDHD5 25348397 N/A physical interaction ComPPI
POLDIP2 NFATC2 25348397 N/A physical interaction ComPPI
POLDIP2 MTMR4 25348397 N/A physical interaction ComPPI
POLDIP2 PTP4A1 25348397 N/A physical interaction ComPPI
POLDIP2 PTPDC1 25348397 N/A physical interaction ComPPI
POLDIP2 TNS2 25348397 N/A physical interaction ComPPI
POLDIP2 CLPX 25348397 N/A physical interaction ComPPI
POLDIP2 NT5DC2 25348397 N/A physical interaction ComPPI
POLDIP2 ZNHIT2 25348397 N/A physical interaction ComPPI
POLDIP2 TSC22D1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
POLDIP2 ESR2 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
POLDIP2 JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
POLDIP2 CLPP 24234451 25348397 26058080 association proximity-dependent biotin identification ComPPI,IntAct
POLDIP2 FASTKD3 20869947 24234451 25348397 association tandem affinity purification ComPPI,IntAct
POLDIP2 DNAAF6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
POLDIP2 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
POLDIP2 AIFM1 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
POLDIP2 AURKAIP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
POLDIP2 HSPD1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
POLDIP2 PDK1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
POLDIP2 TRMT61B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
POLDIP2 FBL 24234451 25348397 29568061 association pull down ComPPI,IntAct
POLDIP2 H3C1 24234451 25348397 29568061 association pull down ComPPI,IntAct
POLDIP2 CANX 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
POLDIP2 SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
POLDIP2 COQ10A 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
POLDIP2 MIX23 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
POLDIP2 ABHD11 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
POLDIP2 MICOS13 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
POLDIP2 PHYHIPL 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
POLDIP2 RCC1L 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
POLDIP2 LYRM4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
POLDIP2 COX6B1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
POLDIP2 GATD3B 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
POLDIP2 OPA3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
POLDIP2 SDHAF4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
POLDIP2 ADCK5 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
MGST3 POLDIP2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct

Visualization










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