Gene Information gene info

GENE:PYCARD

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PYCARD
FullNmae PYD and CARD domain containing
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16608
EnsembleID ENSG00000103490
Uniprot Q9ULZ3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PYCARD pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PYCARD pyroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
PYCARD parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PYCARD necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PYCARD necroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
PYCARD autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PYCARD autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PYCARD autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
PYCARD apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PYCARD apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PYCARD GO:0000139,GO:0001773,GO:0002020,GO:0002218,GO:0002221,GO:0002230,GO:0002277,GO:0002588,GO:0002821,GO:0005138,GO:0005515,GO:0005523,GO:0005576,GO:0005634,GO:0005654,GO:0005730,GO:0005730,GO:0005737,GO:0005737,GO:0005739,GO:0005783,GO:0005829,GO:0005829,GO:0005874,GO:0006915,GO:0006919,GO:0006919,GO:0006954,GO:0007165,GO:0007231,GO:0008385,GO:0008656,GO:0010506,GO:0010803,GO:0017024,GO:0019899,GO:0030838,GO:0031647,GO:0032088,GO:0032090,GO:0032688,GO:0032722,GO:0032729,GO:0032731,GO:0032731,GO:0032731,GO:0032731,GO:0032733,GO:0032755,GO:0032755,GO:0032757,GO:0032760,GO:0032991,GO:0033209,GO:0034774,GO:0035578,GO:0042104,GO:0042771,GO:0042802,GO:0042802,GO:0042803,GO:0043025,GO:0043065,GO:0043124,GO:0043280,GO:0043280,GO:0044325,GO:0044351,GO:0044546,GO:0045087,GO:0046330,GO:0046456,GO:0046983,GO:0050729,GO:0050729,GO:0050729,GO:0050766,GO:0050829,GO:0050830,GO:0050870,GO:0051091,GO:0051092,GO:0051260,GO:0051607,GO:0051607,GO:0060907,GO:0061702,GO:0061702,GO:0061702,GO:0070269,GO:0070374,GO:0070700,GO:0071222,GO:0071347,GO:0071356,GO:0071901,GO:0072332,GO:0072558,GO:0072558,GO:0072559,GO:0072559,GO:0090200,GO:0097169,GO:0097169,GO:0140738,GO:1900016,GO:1901224,GO:2000406,GO:2001056,GO:2001238,GO:2001242

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PYCARD hsa:29108 path:hsa04217 Necroptosis - Homo sapiens (human)
PYCARD hsa:29108 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
PYCARD hsa:29108 path:hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human)
PYCARD hsa:29108 path:hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human)
PYCARD hsa:29108 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
PYCARD hsa:29108 path:hsa05131 Shigellosis - Homo sapiens (human)
PYCARD hsa:29108 path:hsa05132 Salmonella infection - Homo sapiens (human)
PYCARD hsa:29108 path:hsa05133 Pertussis - Homo sapiens (human)
PYCARD hsa:29108 path:hsa05134 Legionellosis - Homo sapiens (human)
PYCARD hsa:29108 path:hsa05135 Yersinia infection - Homo sapiens (human)
PYCARD hsa:29108 path:hsa05164 Influenza A - Homo sapiens (human)
PYCARD hsa:29108 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PYCARD AIM2 19104081 19158675 19158676 21575908 23180781 23702978 26192618 26885855 27048821 27066895 27984721 interaction type,physical association anti tag coimmunoprecipitation,pull down ACSN,InnateDB
PYCARD NLRC4 11967258 14634131 19104081 19337385 23180781 23702978 23940371 24803432 26192618 26885855 27048821 27066895 27984721 interaction type,physical association anti tag coimmunoprecipitation,two hybrid,gst pull down,pull down,fluorescence microscopy ACSN,InnateDB
PYCARD NLRP3 11989976 12615073 15030775 17959595 19104081 19158675 19337385 20385749 21575908 23180781 23202296 23702978 24803432 26192618 26885855 27048821 27066895 27439607 27984721 interaction type,physical association anti tag coimmunoprecipitation,two hybrid,fluorescence microscopy ACSN,InnateDB
PYCARD BAX 14730312 19062087 19104081 19968986 23180781 26192618 26885855 27048821 27066895 27984721 interaction type,physical association anti tag coimmunoprecipitation,pull down ACSN,InnateDB
RHO PYCARD 24919149 26192618 26885855 27048821 27066895 interaction type N/A ACSN
PYCARD IL1B 19104081 20385749 23180781 23202296 24803432 26192618 26885855 27048821 27066895 27439607 27984721 interaction type,physical association fluorescence microscopy ACSN,InnateDB
P2RX7 PYCARD 20086177 26192618 interaction type N/A ACSN
CD14 PYCARD 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 interaction type N/A ACSN
IRAK2 PYCARD 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 interaction type N/A ACSN
IRAK4 PYCARD 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 interaction type N/A ACSN
LY96 PYCARD 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 interaction type N/A ACSN
MYD88 PYCARD 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 interaction type N/A ACSN
TIRAP PYCARD 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 interaction type N/A ACSN
PYCARD CASP1 11967258 14634131 16585594 19337385 21385879 23180781 24803432 physical association anti tag coimmunoprecipitation,two hybrid,gst pull down,pull down,fluorescence microscopy InnateDB
RIPK2 PYCARD 14634131 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
PYCARD NLRP2 15030775 15456791 23180781 physical association anti tag coimmunoprecipitation InnateDB
NLRP3 PYCARD 11786556 15030775 16037825 23180781 25686105 physical association affinity chromatography technology,anti tag coimmunoprecipitation,two hybrid InnateDB
NLRP2 PYCARD 15030775 23180781 23625868 physical association anti tag coimmunoprecipitation InnateDB
MEFV PYCARD 14595024 16037825 17431422 17964261 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,two hybrid InnateDB
PYCARD NLRP10 15096476 23180781 physical association anti tag coimmunoprecipitation InnateDB
PYCARD PYDC1 12656673 17178784 18362139 19337385 23180781 physical association anti tag coimmunoprecipitation,two hybrid,pull down,surface plasmon resonance InnateDB
PYCARD CHUK 12486103 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB PYCARD 12486103 23180781 physical association anti tag coimmunoprecipitation InnateDB
TP53 PYCARD 14730312 23180781 physical association anti tag coimmunoprecipitation InnateDB
NLRC4 PYCARD 12646168 23180781 physical association anti tag coimmunoprecipitation InnateDB
PYCARD PYCARD 19337385 23180781 physical association two hybrid InnateDB
PYCARD DDX58 19915568 23180781 physical association anti tag coimmunoprecipitation InnateDB
NLRP1 PYCARD 21252346 23180781 physical association anti tag coimmunoprecipitation InnateDB
PYCARD IFI16 21575908 23180781 physical association anti tag coimmunoprecipitation InnateDB
DHX33 PYCARD 23180781 23871209 physical association anti tag coimmunoprecipitation InnateDB
DDX58 PYCARD 23180781 23592984 physical association anti tag coimmunoprecipitation InnateDB
PYCARD CASP8 23180781 24803432 physical association fluorescence microscopy InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 PYCARD 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 PYCARD 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F4 PYCARD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PYCARD 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000753AD PYCARD 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000AA464 PYCARD 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 PYCARD 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 PYCARD 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC PYCARD 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 PYCARD 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000049704B PYCARD 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A PYCARD 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 PYCARD 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA PYCARD 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002FF522 PYCARD 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B PYCARD 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 PYCARD 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B PYCARD 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDA4 PYCARD 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004407DC PYCARD 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 PYCARD 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000070B1D PYCARD 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 PYCARD 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PYCARD NLRP12 25361965 interaction type N/A PTMCode2
NLRP12 PYCARD 25361965 interaction type N/A PTMCode2
PYCARD NLRC4 25361965 interaction type N/A PTMCode2
NLRC4 PYCARD 25361965 interaction type N/A PTMCode2
PYCARD CARD16 25361965 interaction type N/A PTMCode2
CARD16 PYCARD 25361965 interaction type N/A PTMCode2
MEFV PYCARD 25361965 interaction type N/A PTMCode2
PYCARD MEFV 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EXOC5 PYCARD 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AIM2 PYCARD 19158675 19158676 22286270 24234451 24237704 24630722 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,electron microscopy,fluorescence polarization spectroscopy,molecular sieving,pull down,physical interaction ComPPI,IntAct
PAK1 PYCARD 24234451 25348397 25402006 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SYK PYCARD 24234451 25348397 25605870 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,protein kinase assay ComPPI,IntAct
IL6ST PYCARD 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SRF PYCARD 10847592 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TMPRSS15 PYCARD 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR1A PYCARD 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CASP1 PYCARD 11967258 12019269 12191486 14525934 24234451 24630722 25348397 25605870 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,electron microscopy,experimental interaction detection,fluorescence polarization spectroscopy,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
LEMD3 PYCARD 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CASP8 PYCARD 22267217 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
IKBKB PYCARD 12486103 24234451 25348397 colocalization,association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
BMPR2 PYCARD 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SQSTM1 PYCARD 22286270 24234451 25348397 colocalization,association anti bait coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
RALB PYCARD 22286270 24234451 25348397 colocalization physical interaction,confocal microscopy ComPPI,IntAct
CUL2 PYCARD 25348397 N/A physical interaction ComPPI
PSTPIP1 PYCARD 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CHUK PYCARD 12486103 24234451 25348397 colocalization,association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
RIPK1 PYCARD 24234451 25348397 25402006 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LIG3 PYCARD 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PYCARD MEFV 11498534 12054656 12646168 14525934 17964261 24234451 25006247 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,imaging technique,in vivo,two hybrid ComPPI,HPRD,IntAct
PYCARD NLRP3 11786556 14525934 15020601 19158675 24234451 24630722 25348397 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,electron microscopy,experimental interaction detection,fluorescence polarization spectroscopy,physical interaction,fluorescence microscopy,in vitro ComPPI,HPRD,IntAct
PYCARD NLRC4 11374873 12646168 14525934 24234451 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PYCARD NLRP12 12019269 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PYCARD NLRP1 14525934 17418785 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
PYCARD PYDC2 14525934 17178784 17339483 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,in vitro,in vivo,confocal microscopy ComPPI,HPRD,IntAct
PYCARD POP1 14525934 17178784 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PYCARD NLRP2 25348397 N/A physical interaction ComPPI
PYCARD BECN1 22286270 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PYCARD DNAJC28 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PYCARD FAM184A 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PYCARD PML 24234451 24407287 25348397 27898060 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
PYCARD INPP4B 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PYCARD CEP131 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PYCARD ARMC2 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PYCARD MYO1C 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PYCARD MCM4 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PYCARD TSHZ2 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PYCARD NUP107 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PYCARD FSTL5 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PYCARD NAA15 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PYCARD DRC7 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PYCARD TPM4 24234451 24407287 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PYCARD IFI16 25348397 N/A physical interaction ComPPI
PYCARD BRCA1 25348397 N/A physical interaction ComPPI
PYCARD USP50 25348397 N/A physical interaction ComPPI
PYCARD CDK15 25348397 N/A physical interaction ComPPI
PYCARD ZYG11B 25348397 N/A physical interaction ComPPI
PYCARD PIGP 25348397 N/A physical interaction ComPPI
PYCARD BIRC5 25348397 N/A physical interaction ComPPI
PYCARD FCF1 25348397 N/A physical interaction ComPPI
PYCARD DDX58 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
PYCARD MALT1 22267217 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PYCARD CARD9 22267217 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PYCARD LAMP1 22286270 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
PYCARD BAX 14730312 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,confocal microscopy ComPPI,IntAct
PYCARD IKBKG 12486103 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PYCARD PYDC1 17178784 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,confocal microscopy ComPPI,IntAct
PYCARD ERVK-19 24234451 24407287 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PYCARD NLRC3 24234451 25277106 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,confocal microscopy ComPPI,IntAct
BCL10 PYCARD 22267217 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ARIH2 PYCARD 25348397 N/A physical interaction ComPPI
PYCARD PYCARD 24234451 24630722 25006247 25416956 physical association anti tag coimmunoprecipitation,electron microscopy,fluorescence polarization spectroscopy,molecular sieving,pull down,two hybrid array IntAct
CASP1 PYCARD 11051551 11432859 11536016 11967258 12019269 12191486 14634131 15383541 16585594 19337385 21385879 24630722 24803432 27898060 inhibition N/A OmniPath
PYCARD CASP1 11967258 12019269 12191486 14634131 16585594 19337385 21385879 24630722 24803432 27898060 stimulant N/A OmniPath
CHUK PYCARD 12486103 27898060 N/A N/A OmniPath
PYCARD CHUK 12486103 27898060 N/A N/A OmniPath
NLRP1 PYCARD 11250163 12191486 17349957 17382568 17418785 19066616 19401709 21252346 27898060 N/A N/A OmniPath
PYCARD RIPK2 14634131 27898060 N/A N/A OmniPath
NLRP3 PYCARD 11250163 11786556 12615073 15020601 15030775 16037825 16407888 17382568 17470531 19158675 19337385 21575908 21994322 22361007 23066025 24630722 24803432 25686105 27898060 N/A N/A OmniPath
PYCARD NLRP3 11250163 11786556 12615073 15020601 15030775 16037825 16407888 17382568 17470531 19158675 19337385 21575908 21994322 22361007 23066025 24630722 24803432 25686105 27898060 N/A N/A OmniPath
COP1 PYCARD 11051551 11432859 11536016 15383541 27898060 inhibition N/A OmniPath
TP53 PYCARD 18431400 27898060 stimulant N/A OmniPath
PYCARD DDX58 19915568 23592984 27898060 N/A N/A OmniPath
CARD18 PYCARD 11051551 11432859 11536016 15383541 27898060 inhibition N/A OmniPath
PYCARD BAX 14730312 16964285 17464323 19062087 19968986 27898060 stimulant N/A OmniPath
NLRC4 PYCARD 11374873 11390368 11967258 12646168 14634131 15701651 17382568 17470531 17696608 19337385 24803432 27898060 N/A N/A OmniPath
PYCARD NLRC4 11374873 11390368 11967258 12646168 14634131 15701651 17382568 17470531 17696608 19337385 24803432 27898060 N/A N/A OmniPath
PYCARD IKBKB 12486103 27898060 N/A N/A OmniPath
PYCARD AIM2 19158675 19158676 21575908 22869553 24237704 24630722 27898060 N/A N/A OmniPath
PYCARD IFI16 21575908 27898060 N/A N/A OmniPath
NLRP10 PYCARD 15096476 20393137 27898060 N/A N/A OmniPath
PYCARD PYDC1 12656673 17178784 18362139 19337385 27898060 N/A N/A OmniPath
MEFV PYCARD 11498534 12054656 12646168 14595024 16037825 17431422 17964261 27898060 inhibition N/A OmniPath
PYCARD MEFV 11498534 12054656 12646168 14595024 16037825 17431422 17964261 27898060 N/A N/A OmniPath
NLRP2 PYCARD 15030775 15456791 17382568 23625868 27898060 N/A N/A OmniPath
CARD17 PYCARD 11051551 11432859 11536016 15383541 27898060 inhibition N/A OmniPath

Visualization