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GENE：RAB39B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RAB39B
FullNmae RAB39B, member RAS oncogene family
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16499
EnsembleID ENSG00000155961
Uniprot Q96DA2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RAB39B autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RAB39B autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RAB39B GO:0003924,GO:0005515,GO:0005525,GO:0005794,GO:0005886,GO:0006914,GO:0010506,GO:0015031,GO:0016192,GO:0016192,GO:0030659,GO:0031489,GO:0031489,GO:0031982,GO:0032482,GO:0043005,GO:0050808

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RAB39B hsa:116442 path:hsa04140 Autophagy - animal - Homo sapiens (human)
RAB39B hsa:116442 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
RAB39B hsa:116442 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 RAB39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RAB39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RAB39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000458AD2 RAB39B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C28B2 RAB39B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000016E46F RAB39B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001C04A2 RAB39B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000057FDB8 RAB39B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000292B1 RAB39B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000029D793 RAB39B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 RAB39B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004F24A9 RAB39B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B RAB39B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A RAB39B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD02D RAB39B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002E92A8 RAB39B 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
KPNA2 RAB39B 25348397 N/A physical interaction ComPPI
GOLGA2 RAB39B 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RAB39B RUFY1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RAB39B ZDHHC17 24234451 24705354 25348397 physical association two hybrid,physical interaction,two hybrid array,luminescence based mammalian interactome mapping ComPPI,IntAct
RAB39B CBL 25348397 N/A physical interaction ComPPI
RAB39B TRIP6 25348397 N/A physical interaction ComPPI
RAB39B SLC15A1 25348397 N/A physical interaction ComPPI
RAB39B RAD50 25348397 N/A physical interaction ComPPI
RAB39B HBS1L 25348397 N/A physical interaction ComPPI
RAB39B ALPI 25348397 N/A physical interaction ComPPI
RAB39B TOMM22 25348397 N/A physical interaction ComPPI
RAB39B CARM1 25348397 N/A physical interaction ComPPI
RAB39B BECN1 24234451 24349490 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct

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