Gene Information gene info

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GENE：RETREG1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RETREG1
FullNmae reticulophagy regulator 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25964
EnsembleID ENSG00000154153
Uniprot Q9H6L5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RETREG1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RETREG1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RETREG1 GO:0000423,GO:0005515,GO:0005730,GO:0005783,GO:0005789,GO:0005801,GO:0007029,GO:0016604,GO:0019233,GO:0030574,GO:0043524,GO:0043524,GO:0043621,GO:0050872,GO:0061709,GO:0061709,GO:0140506

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR RETREG1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RETREG1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 RETREG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RETREG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RETREG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RETREG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RETREG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RETREG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RETREG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000239117 RETREG1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
GABARAPL2 RETREG1 25348397 N/A two hybrid,pull down,physical interaction ComPPI
MAP1LC3B RETREG1 24234451 25348397 26040720 physical association pull down,physical interaction ComPPI,IntAct
CANX RETREG1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
C1QBP RETREG1 25348397 N/A two hybrid,physical interaction ComPPI
SNAPIN RETREG1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
RAB11A RETREG1 25348397 N/A two hybrid,physical interaction ComPPI
GABARAP RETREG1 24234451 25348397 26040720 physical association pull down,physical interaction ComPPI,IntAct
MAP1LC3A RETREG1 25348397 N/A pull down,physical interaction ComPPI
HK1 RETREG1 25348397 N/A two hybrid,physical interaction ComPPI
GABARAPL1 RETREG1 24234451 25348397 26040720 physical association pull down,physical interaction ComPPI,IntAct
RPL26 RETREG1 25348397 N/A two hybrid,physical interaction ComPPI
APP RETREG1 25348397 N/A physical interaction ComPPI
DDAH1 RETREG1 25348397 N/A two hybrid,physical interaction ComPPI
LAPTM4B RETREG1 25348397 N/A physical interaction ComPPI
TIGD1 RETREG1 25348397 N/A two hybrid,physical interaction ComPPI

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