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GENE：RNF41

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RNF41
FullNmae ring finger protein 41
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18401
EnsembleID ENSG00000181852
Uniprot Q9H4P4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RNF41 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RNF41 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RNF41 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
RNF41 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RNF41 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RNF41 GO:0000209,GO:0004842,GO:0004842,GO:0005128,GO:0005135,GO:0005515,GO:0005829,GO:0006914,GO:0008270,GO:0008285,GO:0010498,GO:0016567,GO:0019904,GO:0030336,GO:0030971,GO:0031267,GO:0042802,GO:0043408,GO:0045619,GO:0045637,GO:0045732,GO:0048471,GO:0051865,GO:0051896,GO:0061630,GO:0061630,GO:0071782,GO:0071782,GO:0097191,GO:1901525,GO:2000377,GO:2000379

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RNF41 hsa:10193 path:hsa04144 Endocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF41 BIRC6 14765125 26192618 interaction type N/A ACSN
APP RNF41 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
AR RNF41 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RNF41 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 RNF41 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA RNF41 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RNF41 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RNF41 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 RNF41 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB RNF41 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000345DEB RNF41 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000070B1D RNF41 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000019D79B RNF41 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD RNF41 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D8730 RNF41 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000306C70 RNF41 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000202460 RNF41 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004AE8D3 RNF41 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C RNF41 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000192A75 RNF41 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB RNF41 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C RNF41 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000024B619 RNF41 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002AB575 RNF41 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005FDE70 RNF41 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED RNF41 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000040EC3B RNF41 21572407 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 RNF41 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 RNF41 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000030F801 RNF41 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 RNF41 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 RNF41 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 RNF41 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 RNF41 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D RNF41 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 RNF41 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000038446A RNF41 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 RNF41 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MARK2 RNF41 22135298 phosphorylation N/A PhosphoSite
USP8 RNF41 25361965 interaction type N/A PTMCode2
RNF41 USP8 25361965 interaction type N/A PTMCode2
RNF41 BIRC6 25361965 interaction type N/A PTMCode2
BIRC6 RNF41 25361965 interaction type N/A PTMCode2
ERBB3 RNF41 25361965 interaction type N/A PTMCode2
RNF41 ERBB3 25361965 interaction type N/A PTMCode2
ERBB4 RNF41 25361965 interaction type N/A PTMCode2
RNF41 ERBB4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBASH3A RNF41 25348397 N/A physical interaction ComPPI
UBASH3B RNF41 25348397 N/A physical interaction ComPPI
GIP RNF41 25348397 N/A physical interaction ComPPI
LZTS2 RNF41 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TRIM32 RNF41 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ERBB4 RNF41 11867753 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ZAP70 RNF41 25348397 N/A physical interaction ComPPI
IRS4 RNF41 25348397 N/A physical interaction ComPPI
LEPR RNF41 25348397 N/A physical interaction ComPPI
CACYBP RNF41 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CD247 RNF41 25348397 N/A physical interaction ComPPI
MARK4 RNF41 14676191 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MNAT1 RNF41 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RRM2B RNF41 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
RAD23A RNF41 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HOMER2 RNF41 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DVL2 RNF41 25348397 N/A physical interaction ComPPI
ADRB2 RNF41 25348397 N/A physical interaction ComPPI
MARK2 RNF41 25348397 N/A physical interaction ComPPI
EVI5 RNF41 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TTC1 RNF41 24234451 25036637 25348397 25416956 association,physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
USP8 RNF41 14525934 15314180 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RTN4 RNF41 25348397 N/A physical interaction ComPPI
TSG101 RNF41 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2K RNF41 25348397 N/A physical interaction ComPPI
SF1 RNF41 25348397 N/A physical interaction ComPPI
CREB3 RNF41 25348397 N/A physical interaction ComPPI
PRKN RNF41 25348397 N/A physical interaction ComPPI
UBE2D3 RNF41 25348397 N/A physical interaction ComPPI
H3-3A RNF41 25348397 N/A physical interaction ComPPI
VANGL2 RNF41 25348397 N/A physical interaction ComPPI
RNF41 BIRC6 25348397 N/A physical interaction ComPPI
RNF41 ERBB3 12411582 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
RNF41 UBE2U 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RNF41 UBE2Z 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RNF41 TADA2A 25348397 N/A physical interaction ComPPI
RNF41 ELAVL1 25348397 N/A physical interaction ComPPI
RNF41 APP 25348397 N/A physical interaction ComPPI
RNF41 RNF166 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RNF41 TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RNF41 SUGT1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF41 RFC4 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF41 VPS52 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF41 ARL6IP4 25348397 N/A physical interaction ComPPI
RNF41 C1ORF109 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF41 ISCA2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF41 ASB6 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF41 RCN1 25348397 N/A physical interaction ComPPI
RNF41 KIFC3 25348397 N/A physical interaction ComPPI
RNF41 NPAT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF41 P4HA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF41 LPGAT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF41 N4BP3 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF41 MTCL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF41 CLEC16A 24234451 24949970 25348397 26496610 27898060 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
RNF41 CLASP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF41 C1GALT1C1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF41 ITSN2 25348397 N/A physical interaction ComPPI
RNF41 RASIP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF41 CEP192 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF41 RFWD3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF41 UPF3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF41 NAV1 25348397 N/A physical interaction ComPPI
RNF41 SOGA1 25348397 N/A physical interaction ComPPI
RNF41 LCP1 25348397 N/A physical interaction ComPPI
RNF41 ENOPH1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF41 TACC1 25348397 N/A physical interaction ComPPI
RNF41 BHLHA15 25348397 N/A physical interaction ComPPI
RNF41 ARHGAP19 25348397 N/A physical interaction ComPPI
RNF41 IFIT5 25348397 N/A physical interaction ComPPI
RNF41 ZNF517 25348397 N/A physical interaction ComPPI
RNF41 MTNR1A 24234451 25348397 26514267 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
RNF41 MTNR1B 24234451 25348397 26514267 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
RNF41 VANGL1 25348397 N/A physical interaction ComPPI
RNF41 MAGEL2 25348397 N/A physical interaction ComPPI
RNF41 KDM3B 25348397 N/A physical interaction ComPPI
RNF41 MTURN 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF41 SRR 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IL23A RNF41 25348397 N/A physical interaction ComPPI
RNF41 RNF41 22493164 24234451 25416956 physical association two hybrid array IntAct
FADD RNF41 24234451 30561431 association virotrap IntAct
TANK RNF41 24234451 30561431 association virotrap IntAct
MARK2 RNF41 24259665 27898060 N/A N/A OmniPath

Visualization










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