GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
RUFY4
FullNmae
RUN and FYVE domain containing 4
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:24804
EnsembleID
ENSG00000188282
Uniprot
Q6ZNE9
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
RUFY4
autophagy
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
RUFY4
autophagy
36341760
The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns.
regulator signature
Go Annotation:
GeneSymbol
Go id
RUFY4
GO:0000045,GO:0000045,GO:0005515,GO:0005776,GO:0005776,GO:0016239,GO:0016239,GO:0031410,GO:0032266,GO:0032266,GO:0046872,GO:0071353
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
SMARCA4
RUFY4
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
RUFY4
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
RUFY4
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
TRIM28
RUFY4
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
NDC80
RUFY4
24234451
25348397
25416956
physical association
physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid
ComPPI,IntAct
CDKN2D
RUFY4
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
LNX1
RUFY4
24234451
25348397
25416956
physical association
physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid
ComPPI,IntAct
MAP1LC3C
RUFY4
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
TRAPPC9
RUFY4
25348397
N/A
physical interaction
ComPPI
Visualization