Gene Information gene info

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GENE：SESN3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SESN3
FullNmae sestrin 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23060
EnsembleID ENSG00000149212
Uniprot P58005

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SESN3 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SESN3 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SESN3 GO:0005515,GO:0005634,GO:0005737,GO:0016239,GO:0016684,GO:0031932,GO:0032868,GO:0034198,GO:0038203,GO:0042149,GO:0042593,GO:0046626,GO:0051896,GO:0070728,GO:0071233,GO:1901031,GO:1904262,GO:1904262,GO:1990253

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SESN3 hsa:143686 path:hsa04115 p53 signaling pathway - Homo sapiens (human)
SESN3 hsa:143686 path:hsa04211 Longevity regulating pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SESN3 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 SESN3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SESN3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 SESN3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SESN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SESN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SESN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SESN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SESN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SESN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SESN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SESN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SESN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 SESN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SESN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SESN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HSF1 SESN3 23388456 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000272039 SESN3 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000237AF9 SESN3 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000079F78 SESN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F SESN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000086A4D SESN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 SESN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000020CEC2 SESN3 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003D8730 SESN3 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000306C70 SESN3 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002C28B2 SESN3 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000016E46F SESN3 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C04A2 SESN3 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 SESN3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB SESN3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002FB065 SESN3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B7E30 SESN3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D SESN3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D SESN3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 SESN3 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 SESN3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000032BD73 SESN3 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD SESN3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000018E72A SESN3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 SESN3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F SESN3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 SESN3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 SESN3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005E6F45 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002FF522 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000081E1F SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000610EFA SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004ACAAA SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000140295 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005E1A16 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDA4 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000006BE7D SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000060AABB SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000BD1DE SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000412AC7 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000759EB8 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000024B619 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001F9A0F SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004F507C SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003BBF48 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000521626 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000000C73C SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000003BF62 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000192A75 SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D SESN3 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RNF2 SESN3 25348397 N/A physical interaction ComPPI
MYCBP2 SESN3 25348397 N/A physical interaction ComPPI
ELAVL1 SESN3 25348397 N/A physical interaction ComPPI
WDR24 SESN3 24234451 25263562 25348397 26449471 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NPRL3 SESN3 24234451 25263562 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
WDR59 SESN3 24234451 25263562 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SESN3 ZFP1 25348397 N/A physical interaction ComPPI

Visualization










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