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GENE：SYNPO2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SYNPO2
FullNmae synaptopodin 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17732
EnsembleID ENSG00000172403
Uniprot Q9UMS6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SYNPO2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SYNPO2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SYNPO2 GO:0001725,GO:0001725,GO:0003779,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005829,GO:0005925,GO:0005925,GO:0015629,GO:0015629,GO:0030018,GO:0030018,GO:0030018,GO:0031005,GO:0032233,GO:0043231,GO:0051371,GO:0051393,GO:0071889

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SYNPO2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 SYNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SYNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SYNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SYNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SYNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SYNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SYNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SYNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SYNPO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 SYNPO2 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000016FD1A SYNPO2 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS00002E92A8 SYNPO2 22100165 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HSPA8 SYNPO2 25348397 N/A physical interaction ComPPI
IPO13 SYNPO2 25348397 N/A physical interaction ComPPI
BAG3 SYNPO2 25348397 N/A physical interaction ComPPI
CDK6 SYNPO2 22094256 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
YWHAG SYNPO2 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FLNC SYNPO2 25348397 N/A physical interaction ComPPI
RHOA SYNPO2 25348397 N/A physical interaction ComPPI
FLNA SYNPO2 25348397 N/A physical interaction ComPPI
YWHAZ SYNPO2 25348397 N/A physical interaction ComPPI
NTRK1 SYNPO2 25348397 N/A physical interaction ComPPI
ILK SYNPO2 21643011 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,two hybrid,pull down,confocal microscopy ComPPI,IntAct,OmniPath
SQSTM1 SYNPO2 25348397 N/A physical interaction ComPPI
ACTN2 SYNPO2 25348397 N/A physical interaction ComPPI
MAP1LC3A SYNPO2 25348397 N/A physical interaction ComPPI
WNK1 SYNPO2 20936779 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PLK4 SYNPO2 25348397 N/A physical interaction ComPPI
ATG16L1 SYNPO2 25348397 N/A physical interaction ComPPI
POLK SYNPO2 25348397 N/A physical interaction ComPPI

Visualization










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