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GENE：TMEM39A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TMEM39A
FullNmae transmembrane protein 39A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25600
EnsembleID ENSG00000176142
Uniprot Q9NV64

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TMEM39A autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TMEM39A autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TMEM39A autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TMEM39A GO:0005515,GO:0005789,GO:0005789,GO:0006914,GO:0045070,GO:1901097,GO:1901097,GO:1902902,GO:1902902

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 TMEM39A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 TMEM39A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TMEM39A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 TMEM39A 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TMEM39A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TMEM39A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 TMEM39A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TMEM39A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CDH5 TMEM39A 25348397 N/A physical interaction ComPPI
TNFSF13B TMEM39A 25348397 N/A physical interaction ComPPI
TENT5A TMEM39A 25348397 N/A physical interaction ComPPI
CHRND TMEM39A 25348397 N/A physical interaction ComPPI
IL9R TMEM39A 25348397 N/A physical interaction ComPPI
IL17RC TMEM39A 25348397 N/A physical interaction ComPPI
TMEM39A TM2D2 25348397 N/A physical interaction ComPPI

Visualization










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