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GENE：TMEM39B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TMEM39B
FullNmae transmembrane protein 39B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25510
EnsembleID ENSG00000121775
Uniprot Q9GZU3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TMEM39B autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TMEM39B autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TMEM39B GO:0005789,GO:0008150,GO:0016020

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR TMEM39B 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TMEM39B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 TMEM39B 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 TMEM39B 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TMEM39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TMEM39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TMEM39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TMEM39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TMEM39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TMEM39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 TMEM39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 TMEM39B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
UBC TMEM39B 25348397 N/A physical interaction ComPPI
IL13RA1 TMEM39B 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SEMA7A TMEM39B 25348397 N/A physical interaction ComPPI
TMEM39B NRG1 25348397 N/A physical interaction ComPPI

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