GENE:TRIM38
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TRIM38 |
| FullNmae | tripartite motif containing 38 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10059 |
| EnsembleID | ENSG00000112343 |
| Uniprot | O00635 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TRIM38 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TRIM38 | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TRIM38 | GO:0000209,GO:0003713,GO:0005515,GO:0005575,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0008270,GO:0010508,GO:0016567,GO:0016925,GO:0019901,GO:0032648,GO:0032880,GO:0042803,GO:0043123,GO:0043123,GO:0043123,GO:0043161,GO:0045070,GO:0045087,GO:0045893,GO:0046596,GO:0046598,GO:0050687,GO:0051091,GO:0051092,GO:0051092,GO:0061630,GO:0061630 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| IRF8 | TRIM38 | 22096565 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| TRIM38 | AZI2 | 22539786 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| TRIM38 | ELAVL1 | 19322201 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | TRIM38 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA1 | TRIM38 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | TRIM38 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | TRIM38 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | TRIM38 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | TRIM38 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | TRIM38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | TRIM38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TRIM38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | TRIM38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | TRIM38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | TRIM38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TRIM38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | TRIM38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | TRIM38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | TRIM38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | TRIM38 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000009262D | TRIM38 | 18591254 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000009C45F | TRIM38 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001E96DA | TRIM38 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006DA05 | TRIM38 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018E72A | TRIM38 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027352D | TRIM38 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000753AD | TRIM38 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000544FF1 | TRIM38 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000048D44E | TRIM38 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS0000086A4D | TRIM38 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | TRIM38 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000031BC7D | TRIM38 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GMCL1 | TRIM38 | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
| BYSL | TRIM38 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| UBE2I | TRIM38 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM38 | EIF1B | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
| TRIM38 | HSPA8 | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| TRIM38 | HSPA2 | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| TRIM38 | TSPYL4 | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| TRIM38 | RIPK1 | 11854271 14525934 24234451 25348397 | physical association | two hybrid,coimmunoprecipitation,experimental interaction detection,in vivo,two hybrid | ComPPI,HPRD,IntAct |
| TRIM38 | UBE2U | 19690564 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| TRIM38 | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM38 | UBE2D1 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM38 | UBE2D2 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM38 | UBE2D3 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM38 | UBE2D4 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM38 | UBE2E1 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM38 | UBE2E2 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM38 | UBE2E3 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM38 | TRAF6 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM38 | ATXN1 | 23275563 24234451 25348397 | physical association | physical interaction,two hybrid prey pooling approach | ComPPI,IntAct |
| TRIM38 | TICAM1 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM38 | HSPA1A | 21988832 23414517 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid fragment pooling approach | ComPPI,IntAct |
| TRIM38 | HSPA1B | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
| TRIM38 | TAB2 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM38 | TAB3 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM38 | RFC5 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| TRIM38 | SDCBP | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| TRIM38 | STXBP1 | 24234451 25348397 25416956 25910212 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid | ComPPI,IntAct |
| TRIM38 | GORASP2 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| TRIM38 | GMCL2 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM38 | AZI2 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM38 | PIAS4 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TRIM38 | SUMO1P1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TRIM38 | RNF4 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TRIM38 | HSPA1L | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TRIM38 | PSMA4 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TRIM38 | TCEA2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TRIM38 | ZNF764 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TRIM38 | MTURN | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TRIM38 | TRIM38 | 24234451 25416956 | physical association | two hybrid array | IntAct |
| TRIM38 | AZI2 | 22539786 27898060 | N/A | N/A | OmniPath |
