GENE：TRIM6
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TRIM6 |
| FullNmae | tripartite motif containing 6 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:16277 |
| EnsembleID | ENSG00000121236 |
| Uniprot | Q9C030 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TRIM6 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TRIM6 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TRIM6 | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TRIM6 | GO:0000209,GO:0002230,GO:0002720,GO:0005515,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0008270,GO:0010508,GO:0010629,GO:0010800,GO:0010994,GO:0010994,GO:0016567,GO:0019901,GO:0019901,GO:0030674,GO:0032496,GO:0032880,GO:0033138,GO:0035458,GO:0042802,GO:0042803,GO:0043123,GO:0045071,GO:0045087,GO:0045892,GO:0046596,GO:0051092,GO:0060340,GO:0060340,GO:0061630,GO:0061630,GO:0061630,GO:0098586,GO:0140297,GO:0140374,GO:1990782,GO:2000679,GO:2000737 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000003ABC4 | TRIM6 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00004F2EB0 | TRIM6 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C4DB5 | TRIM6 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | TRIM6 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD002 | TRIM6 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | TRIM6 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000355E82 | TRIM6 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LGALS3 | TRIM6 | 25348397 | N/A | physical interaction | ComPPI |
| MYC | TRIM6 | 22328504 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| TRIM23 | TRIM6 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM28 | TRIM6 | 25348397 | N/A | physical interaction | ComPPI |
| LGALS8 | TRIM6 | 25348397 | N/A | physical interaction | ComPPI |
| IKBKE | TRIM6 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM5 | TRIM6 | 11331580 16775307 16828831 25348397 27898060 | N/A | two hybrid,physical interaction | ComPPI,OmniPath |
| TRIM6 | IMPDH1 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM6 | TRIM6 | 11331580 14525934 | N/A | experimental interaction detection,two hybrid | HPRD |
| TRIM6 | IKBKE | 24882218 27898060 | N/A | N/A | OmniPath |