GENE:TRIM68
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | TRIM68 |
FullNmae | tripartite motif containing 68 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:21161 |
EnsembleID | ENSG00000167333 |
Uniprot | Q6AZZ1 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
TRIM68 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
TRIM68 | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
TRIM68 | GO:0000209,GO:0004842,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005730,GO:0005737,GO:0005737,GO:0005794,GO:0005829,GO:0005829,GO:0005829,GO:0008270,GO:0010508,GO:0019901,GO:0032880,GO:0035035,GO:0042802,GO:0042803,GO:0043123,GO:0045087,GO:0046596,GO:0048471,GO:0050681,GO:0051092,GO:0051865,GO:0060765,GO:0061630 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ETS1 | TRIM68 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
YBX1 | TRIM68 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
SMARCA4 | TRIM68 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | TRIM68 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | TRIM68 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00000F31F4 | TRIM68 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000B59A2 | TRIM68 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS000003ABC4 | TRIM68 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS0000098B3B | TRIM68 | 22805767 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
URS0000076995 | TRIM68 | 22805767 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
URS00006DE17B | TRIM68 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075C4B1 | TRIM68 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002075FA | TRIM68 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
LENG1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
VIM | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
IFI30 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
TMEM139 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
GRAP2 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
VEGFB | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
AR | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
HSP90B1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
PILRA | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
HNRNPL | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
CCN2 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
COLQ | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
GPS2 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
UBE2D3 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
GNRH1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
TFG | TRIM68 | 24999993 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
NLRP1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
BTN1A1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
PLPP1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
LNX1 | TRIM68 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
AGFG2 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
INCA1 | TRIM68 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
POLR2G | TRIM68 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
AHDC1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
KAT5 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
PRELP | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
CCN5 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
NTF4 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
TRIM68 | UBE2U | 19690564 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
TRIM68 | COLEC11 | 25348397 | N/A | physical interaction | ComPPI |
TRIM68 | PRSS48 | 25348397 | N/A | physical interaction | ComPPI |
TRIM68 | MMP28 | 25348397 | N/A | physical interaction | ComPPI |
TRIM68 | GCNT2 | 25348397 | N/A | physical interaction | ComPPI |
TRIM68 | IGLL5 | 25348397 | N/A | physical interaction | ComPPI |
TRIM68 | AUNIP | 25348397 | N/A | physical interaction | ComPPI |
TRIM68 | SMR3A | 25348397 | N/A | physical interaction | ComPPI |
TRIM68 | NUDT16L1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
TRIM68 | ZBTB42 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
TRIM68 | KRTAP13-2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
TRIM68 | LZTFL1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
C1ORF105 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
KRTAP13-3 | TRIM68 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
TRIM68 | TRIM68 | 24234451 | physical association | two hybrid array,two hybrid prey pooling approach | IntAct |