GENE:TRIM68
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TRIM68 |
| FullNmae | tripartite motif containing 68 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:21161 |
| EnsembleID | ENSG00000167333 |
| Uniprot | Q6AZZ1 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TRIM68 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TRIM68 | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TRIM68 | GO:0000209,GO:0004842,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005730,GO:0005737,GO:0005737,GO:0005794,GO:0005829,GO:0005829,GO:0005829,GO:0008270,GO:0010508,GO:0019901,GO:0032880,GO:0035035,GO:0042802,GO:0042803,GO:0043123,GO:0045087,GO:0046596,GO:0048471,GO:0050681,GO:0051092,GO:0051865,GO:0060765,GO:0061630 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | TRIM68 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | TRIM68 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | TRIM68 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TRIM68 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | TRIM68 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000F31F4 | TRIM68 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000B59A2 | TRIM68 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000003ABC4 | TRIM68 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000098B3B | TRIM68 | 22805767 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS0000076995 | TRIM68 | 22805767 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS00006DE17B | TRIM68 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | TRIM68 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002075FA | TRIM68 | 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LENG1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| VIM | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| IFI30 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| TMEM139 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| GRAP2 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| VEGFB | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| AR | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| HSP90B1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| PILRA | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| CCN2 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| COLQ | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| GPS2 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2D3 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| GNRH1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| TFG | TRIM68 | 24999993 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| NLRP1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| BTN1A1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| PLPP1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| LNX1 | TRIM68 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AGFG2 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| INCA1 | TRIM68 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| POLR2G | TRIM68 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AHDC1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| KAT5 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| PRELP | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| CCN5 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| NTF4 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM68 | UBE2U | 19690564 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| TRIM68 | COLEC11 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM68 | PRSS48 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM68 | MMP28 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM68 | GCNT2 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM68 | IGLL5 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM68 | AUNIP | 25348397 | N/A | physical interaction | ComPPI |
| TRIM68 | SMR3A | 25348397 | N/A | physical interaction | ComPPI |
| TRIM68 | NUDT16L1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TRIM68 | ZBTB42 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TRIM68 | KRTAP13-2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TRIM68 | LZTFL1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| C1ORF105 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| KRTAP13-3 | TRIM68 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TRIM68 | TRIM68 | 24234451 | physical association | two hybrid array,two hybrid prey pooling approach | IntAct |
