Gene Information gene info

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GENE：UBA5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UBA5
FullNmae ubiquitin like modifier activating enzyme 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23230
EnsembleID ENSG00000081307
Uniprot Q9GZZ9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UBA5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UBA5 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UBA5 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
UBA5 GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0005737,GO:0005789,GO:0005794,GO:0005829,GO:0005829,GO:0008270,GO:0030218,GO:0030219,GO:0033146,GO:0034976,GO:0034976,GO:0042803,GO:0043231,GO:0050905,GO:0051179,GO:0061709,GO:0061912,GO:0061912,GO:0071566,GO:0071566,GO:0071566,GO:0071569,GO:0071569,GO:0071569,GO:1990592

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR UBA5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
HIF1A UBA5 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 UBA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UBA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UBA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 UBA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UBA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 UBA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UBA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 UBA5 22012620 22291592 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000B59A2 UBA5 22012620 22291592 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 UBA5 22012620 22291592 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
UFM1 UBA5 25361965 interaction type N/A PTMCode2
UBA5 UFM1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNW1 UBA5 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L UBA5 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ATP6V1D UBA5 25348397 N/A physical interaction ComPPI
CBSL UBA5 25348397 N/A physical interaction ComPPI
RPS28 UBA5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GOLGA1 UBA5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VCP UBA5 25348397 N/A physical interaction ComPPI
GABARAPL2 UBA5 14525934 16189514 20562859 21900206 24234451 25348397 25416956 association,physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
ZNF512B UBA5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCM2 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAP1LC3B UBA5 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
PNMA1 UBA5 25348397 N/A physical interaction ComPPI
DDX17 UBA5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SND1 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACOX1 UBA5 25348397 N/A physical interaction ComPPI
PGM1 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSP90B1 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DBNL UBA5 25348397 N/A physical interaction ComPPI
PA2G4 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPB2 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CYTH1 UBA5 25348397 N/A physical interaction ComPPI
XPO1 UBA5 25348397 N/A physical interaction ComPPI
NAE1 UBA5 25348397 N/A physical interaction ComPPI
FKBP4 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YBX3 UBA5 25348397 N/A physical interaction ComPPI
GABARAP UBA5 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
TP53RK UBA5 25348397 N/A physical interaction ComPPI
PSMD2 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CRMP1 UBA5 25348397 N/A physical interaction ComPPI
PLIN3 UBA5 25348397 N/A physical interaction ComPPI
PGK1 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPE1 UBA5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PECR UBA5 25348397 N/A physical interaction ComPPI
NCBP2 UBA5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NSFL1C UBA5 25348397 N/A physical interaction ComPPI
PDCD6IP UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX39A UBA5 25348397 N/A physical interaction ComPPI
GANAB UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3A UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ALYREF UBA5 25348397 N/A physical interaction ComPPI
PRDX3 UBA5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPL17 UBA5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHMT2 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BOLL UBA5 25348397 N/A physical interaction ComPPI
SH3GLB2 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ALDH2 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DUSP13 UBA5 25348397 N/A physical interaction ComPPI
APEH UBA5 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ECHS1 UBA5 25348397 N/A physical interaction ComPPI
GSTO1 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KLHL8 UBA5 25348397 N/A physical interaction ComPPI
UBA5 ATG101 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA5 UFM1 15071506 20562859 21304510 24234451 24966333 25348397 26496610 27898060 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
UBA5 UFC1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA5 SARS1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA5 LTA4H 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA5 TARS1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA5 CBR1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA5 HSD17B4 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA5 ALDH7A1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA5 SFXN1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA5 ETFA 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA5 FARSB 25348397 N/A physical interaction ComPPI
UBA5 NAA15 25348397 N/A physical interaction ComPPI
UBA5 LAP3 25348397 N/A physical interaction ComPPI
UBA5 THTPA 25348397 N/A physical interaction ComPPI
UBA5 USP5 25348397 N/A physical interaction ComPPI
UBA5 CCT8 25348397 N/A physical interaction ComPPI
UBA5 HK1 25348397 N/A physical interaction ComPPI
UBA5 NUDCD1 25348397 N/A physical interaction ComPPI
UBA5 CDC20B 25348397 N/A physical interaction ComPPI
UBA5 MREG 25348397 N/A physical interaction ComPPI
UBA5 IPP 25348397 N/A physical interaction ComPPI
UBA5 P4HA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA5 MOGS 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA5 ANP32E 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA5 JPT2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA5 MZT2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA5 DUSP13 25348397 N/A physical interaction ComPPI
UBA5 REXO5 25348397 N/A physical interaction ComPPI
UBA5 GAPDHS 25348397 N/A physical interaction ComPPI
UBA5 SLX4 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
UBA5 GABARAPL1 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
UBA5 MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
CBS UBA5 25348397 N/A physical interaction ComPPI
HADH UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FGL1 UBA5 25348397 N/A physical interaction ComPPI
UBA5 UBA5 20562859 24234451 physical association anti tag coimmunoprecipitation IntAct

Visualization










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