Gene Information gene info

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GENE：UFC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UFC1
FullNmae ubiquitin-fold modifier conjugating enzyme 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26941
EnsembleID ENSG00000143222
Uniprot Q9Y3C8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UFC1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UFC1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
UFC1 GO:0005515,GO:0007420,GO:0034976,GO:0034976,GO:0061657,GO:0061709,GO:0070062,GO:0071568,GO:0071569,GO:0071569,GO:1990592,GO:1990592

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 UFC1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A UFC1 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 UFC1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 UFC1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SPI1 UFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 UFC1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EC1BE UFC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000015B295 UFC1 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
UFM1 UFC1 25361965 interaction type N/A PTMCode2
UFC1 UFM1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ZNRD2 UFC1 25348397 N/A physical interaction ComPPI
LDHB UFC1 25348397 N/A physical interaction ComPPI
CLNS1A UFC1 25348397 N/A physical interaction ComPPI
FKBP1A UFC1 25348397 N/A physical interaction ComPPI
CDK5RAP3 UFC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
COX17 UFC1 25348397 N/A physical interaction ComPPI
ZYX UFC1 25348397 N/A physical interaction ComPPI
UBA52 UFC1 25348397 N/A physical interaction ComPPI
VCL UFC1 25348397 N/A physical interaction ComPPI
NEDD8 UFC1 25348397 N/A physical interaction ComPPI
SPR UFC1 25348397 N/A physical interaction ComPPI
VHL UFC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PCMT1 UFC1 25348397 N/A physical interaction ComPPI
UBE2H UFC1 25348397 N/A physical interaction ComPPI
TALDO1 UFC1 25348397 N/A physical interaction ComPPI
SOD1 UFC1 25348397 N/A physical interaction ComPPI
UBA3 UFC1 25348397 N/A physical interaction ComPPI
KIRREL3 UFC1 24234451 25348397 25902260 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,fluorescence microscopy ComPPI,IntAct
CAT UFC1 25348397 N/A physical interaction ComPPI
YKT6 UFC1 25348397 N/A physical interaction ComPPI
UBA5 UFC1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTAQ1 UFC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NECAP2 UFC1 25348397 N/A physical interaction ComPPI
HINT1 UFC1 25348397 N/A physical interaction ComPPI
PSMC2 UFC1 25348397 N/A physical interaction ComPPI
UBXN1 UFC1 25348397 N/A physical interaction ComPPI
TKT UFC1 25348397 N/A physical interaction ComPPI
ZPR1 UFC1 25348397 N/A physical interaction ComPPI
CRIP1 UFC1 25348397 N/A physical interaction ComPPI
LYPLA2 UFC1 25348397 N/A physical interaction ComPPI
ETFA UFC1 25348397 N/A physical interaction ComPPI
NECAP1 UFC1 25348397 N/A physical interaction ComPPI
AHCYL1 UFC1 25348397 N/A physical interaction ComPPI
CAPG UFC1 25348397 N/A physical interaction ComPPI
GEMIN4 UFC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
USP9X UFC1 25348397 N/A physical interaction ComPPI
UFM1 UFC1 25348397 N/A physical interaction ComPPI
UFC1 USP34 25348397 N/A physical interaction ComPPI
UFC1 ATP6V1F 25348397 N/A physical interaction ComPPI
UFC1 UNK 25348397 N/A physical interaction ComPPI
UFC1 ZFYVE19 25348397 N/A physical interaction ComPPI
UFC1 TTC9C 25348397 N/A physical interaction ComPPI
UFC1 UBXN7 25348397 N/A physical interaction ComPPI
UFC1 DDRGK1 25348397 N/A physical interaction ComPPI
UFC1 TAGLN2 25348397 N/A physical interaction ComPPI
TYMS UFC1 25348397 N/A physical interaction ComPPI
ATP6V1B2 UFC1 25348397 N/A physical interaction ComPPI

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