GENE：UFL1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | UFL1 |
| FullNmae | UFM1 specific ligase 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:23039 |
| EnsembleID | ENSG00000014123 |
| Uniprot | O94874 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| UFL1 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| UFL1 | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| UFL1 | GO:0000077,GO:0001649,GO:0005515,GO:0005634,GO:0005737,GO:0005741,GO:0005783,GO:0005789,GO:0005789,GO:0005829,GO:0006281,GO:0008284,GO:0010508,GO:0016020,GO:0019901,GO:0030218,GO:0031397,GO:0032088,GO:0032434,GO:0032434,GO:0032880,GO:0032991,GO:0033146,GO:0034976,GO:0034976,GO:0035861,GO:0043005,GO:0043066,GO:0043122,GO:0050727,GO:0060218,GO:0060252,GO:0061666,GO:0061709,GO:0071568,GO:0071569,GO:0071569,GO:1902065,GO:1903895,GO:1990592,GO:1990592 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SMARCA4 | UFL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | UFL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | UFL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ETS1 | UFL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | UFL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | UFL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | UFL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | UFL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000338542 | UFL1 | N/A | rna interference,inhibition | experimental interaction detection | miRSponge |
| URS0000338542 | UFL1 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection,experimental interaction detection,experimental interaction detection | TarBase |
| URS00000EC1BE | UFL1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004DA9DB | UFL1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000013E79D | UFL1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005A8ED | UFL1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000237AF9 | UFL1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000042B108 | UFL1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001B0D1E | UFL1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000009265 | UFL1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000058863C | UFL1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| UBE2D1 | UFL1 | 19690564 24234451 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| CDK5RAP3 | UFL1 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| UBE2E3 | UFL1 | 19690564 24234451 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| UBE2D4 | UFL1 | 19690564 24234451 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| JUN | UFL1 | 24234451 25348397 25609649 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| UBE2D2 | UFL1 | 19690564 24234451 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| NTRK1 | UFL1 | 25348397 | N/A | physical interaction | ComPPI |
| CANX | UFL1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| TNF | UFL1 | 25348397 | N/A | physical interaction | ComPPI |
| ABCE1 | UFL1 | 25348397 | N/A | physical interaction | ComPPI |
| EGFR | UFL1 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2D3 | UFL1 | 19690564 24234451 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| CASP4 | UFL1 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ZNF622 | UFL1 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2E1 | UFL1 | 19690564 24234451 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| SENP3 | UFL1 | 25348397 | N/A | physical interaction | ComPPI |
| FUS | UFL1 | 25348397 | N/A | physical interaction | ComPPI |
| AHSA1 | UFL1 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2W | UFL1 | 19690564 24234451 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| PTP4A3 | UFL1 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| BSG | UFL1 | 25348397 | N/A | physical interaction | ComPPI |
| TACE | UFL1 | 25348397 | N/A | two hybrid | ComPPI |
| UFL1 | TSL | 25348397 | N/A | two hybrid | ComPPI |
| UFL1 | BTK29A | 25348397 | N/A | two hybrid | ComPPI |
| H2BC5 | UFL1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| H2BC21 | UFL1 | 24234451 30021884 | physical association | cross-linking study | IntAct |