GENE：VPS13D
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | VPS13D |
| FullNmae | vacuolar protein sorting 13 homolog D |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:23595 |
| EnsembleID | ENSG00000048707 |
| Uniprot | Q5THJ4 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| VPS13D | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| VPS13D | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| VPS13D | GO:0006623,GO:0006869,GO:0007005,GO:0007005,GO:0019898,GO:0045053,GO:0070062,GO:1901526 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | VPS13D | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | VPS13D | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | VPS13D | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | VPS13D | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | VPS13D | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | VPS13D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | VPS13D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | VPS13D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | VPS13D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | VPS13D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | VPS13D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | VPS13D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | VPS13D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | VPS13D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | VPS13D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | VPS13D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | VPS13D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | VPS13D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | VPS13D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | VPS13D | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000028BB8 | VPS13D | 17612493 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000148B91 | VPS13D | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000016D2D4 | VPS13D | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000000B1C9 | VPS13D | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000076B539 | VPS13D | 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | VPS13D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075E2C3 | VPS13D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000004BACE | VPS13D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000047944F | VPS13D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002F0130 | VPS13D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000004CA3 | VPS13D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003CF1AD | VPS13D | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TOMM22 | VPS13D | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| PPP2R1A | VPS13D | 25348397 | N/A | physical interaction | ComPPI |
| GSK3B | VPS13D | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| PSMC1 | VPS13D | 25348397 | N/A | physical interaction | ComPPI |
| ESR1 | VPS13D | 21182205 24234451 25348397 | association | cosedimentation through density gradient,physical interaction | ComPPI,IntAct |
| TOMM20 | VPS13D | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| DALLY | VPS13D | 24234451 25294943 25348397 | association | pull down | ComPPI,IntAct |