GENE：WASHC1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | WASHC1 |
| FullNmae | WASH complex subunit 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:24361 |
| EnsembleID | ENSG00000181404 |
| Uniprot | A8K0Z3 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| WASHC1 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| WASHC1 | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| WASHC1 | GO:0003779,GO:0005515,GO:0005769,GO:0005769,GO:0005769,GO:0005770,GO:0005776,GO:0005814,GO:0005829,GO:0006887,GO:0006887,GO:0010507,GO:0015031,GO:0016197,GO:0016197,GO:0022617,GO:0030335,GO:0031274,GO:0031396,GO:0031625,GO:0031901,GO:0032456,GO:0032456,GO:0034314,GO:0034314,GO:0034314,GO:0034315,GO:0042147,GO:0042147,GO:0042147,GO:0043014,GO:0043014,GO:0043015,GO:0043553,GO:0055037,GO:0055037,GO:0055038,GO:0071203,GO:0071203,GO:0071203 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| WASHC1 | hsa:100287171 | path:hsa04144 | Endocytosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| YBX1 | WASHC1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| EXOC8 | WASHC1 | 24234451 24344185 25348397 | physical association | anti bait coimmunoprecipitation,two hybrid fragment pooling approach,proximity ligation assay | ComPPI,IntAct |
| SNX1 | WASHC1 | 20923837 24234451 25348397 | colocalization | fluorescence microscopy | ComPPI,IntAct |
| SQSTM1 | WASHC1 | 23974797 24234451 25348397 | colocalization | fluorescence microscopy | ComPPI,IntAct |
| EXOC4 | WASHC1 | 24234451 24344185 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| CTTN | WASHC1 | 24234451 24344185 25348397 | colocalization,physical association | fluorescence microscopy,proximity ligation assay | ComPPI,IntAct |
| RNF2 | WASHC1 | 25348397 | N/A | physical interaction | ComPPI |
| BECN1 | WASHC1 | 23974797 24234451 25348397 | colocalization,physical association | anti bait coimmunoprecipitation,physical interaction,fluorescence microscopy | ComPPI,IntAct |
| BLOC1S2 | WASHC1 | 25348397 | N/A | physical interaction | ComPPI |
| CEP152 | WASHC1 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| ALAS1 | WASHC1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| WASHC1 | WASHC2A | 25348397 | N/A | physical interaction | ComPPI |
| TRIM27 | WASHC1 | 23452853 27898060 | stimulant | N/A | OmniPath |