Gene Information gene info

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GENE：WDR41

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol WDR41
FullNmae WD repeat domain 41
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25601
EnsembleID ENSG00000164253
Uniprot Q9HAD4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
WDR41 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
WDR41 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
WDR41 GO:0005085,GO:0005515,GO:0005737,GO:0005737,GO:0005765,GO:0006914,GO:0010506,GO:0010506,GO:0032045,GO:0032045,GO:0043547,GO:0045920,GO:0050777

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
WDR41 hsa:55255 path:hsa04140 Autophagy - animal - Homo sapiens (human)
WDR41 hsa:55255 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
WDR41 hsa:55255 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 WDR41 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 WDR41 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 WDR41 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA WDR41 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF WDR41 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 WDR41 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 WDR41 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 WDR41 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 WDR41 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 WDR41 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 WDR41 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001919B0 WDR41 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000215483 WDR41 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 WDR41 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 WDR41 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E WDR41 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TOMM22 WDR41 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CANX WDR41 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NPHP1 WDR41 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
DNAJC7 WDR41 25348397 N/A physical interaction ComPPI
MMS19 WDR41 25348397 N/A physical interaction ComPPI
RAB9A WDR41 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RB1CC1 WDR41 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TOMM20 WDR41 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TGOLN2 WDR41 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TKT WDR41 25348397 N/A physical interaction ComPPI
PTBP3 WDR41 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MRAP2 WDR41 25348397 N/A physical interaction ComPPI
TSPAN5 WDR41 25348397 N/A physical interaction ComPPI

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