GENE：WDR81
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | WDR81 |
| FullNmae | WD repeat domain 81 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:26600 |
| EnsembleID | ENSG00000167716 |
| Uniprot | Q562E7 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| WDR81 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| WDR81 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| WDR81 | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| WDR81 | GO:0000421,GO:0005515,GO:0005739,GO:0005739,GO:0005765,GO:0005829,GO:0006511,GO:0007005,GO:0010008,GO:0031901,GO:0031902,GO:0035014,GO:0035014,GO:0035973,GO:0035973,GO:0043551,GO:0045022,GO:0050821,GO:0070530 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | WDR81 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ESR1 | WDR81 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | WDR81 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | WDR81 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | WDR81 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | WDR81 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | WDR81 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | WDR81 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | WDR81 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | WDR81 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ETS1 | WDR81 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | WDR81 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | WDR81 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | WDR81 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | WDR81 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | WDR81 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000160683 | WDR81 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075ABF4 | WDR81 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000009A9A2 | WDR81 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000195F5B | WDR81 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A608 | WDR81 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000033B91D | WDR81 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005A8A8D | WDR81 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000CC005 | WDR81 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000017DBB8 | WDR81 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C85B2 | WDR81 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FC5B0 | WDR81 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A7F58 | WDR81 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B989F | WDR81 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| BLNK | WDR81 | 25348397 | N/A | physical interaction | ComPPI |
| PPP4C | WDR81 | 25348397 | N/A | physical interaction | ComPPI |
| CUL3 | WDR81 | 25348397 | N/A | physical interaction | ComPPI |
| UBC | WDR81 | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | WDR81 | 25348397 | N/A | physical interaction | ComPPI |
| ENO1 | WDR81 | 25348397 | N/A | physical interaction | ComPPI |
| PPP1CA | WDR81 | 19389623 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| SQSTM1 | WDR81 | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | WDR81 | 25348397 | N/A | physical interaction | ComPPI |
| MAPK15 | WDR81 | 23602568 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| BECN1 | WDR81 | 25348397 | N/A | physical interaction | ComPPI |
| NUDC | WDR81 | 24234451 25036637 25348397 | physical association | luminescence based mammalian interactome mapping | ComPPI,IntAct |
| SHMT2 | WDR81 | 25348397 | N/A | physical interaction | ComPPI |
| NXF1 | WDR81 | 25348397 | N/A | physical interaction | ComPPI |
| MOV10 | WDR81 | 25348397 | N/A | physical interaction | ComPPI |
| MAP1LC3C | WDR81 | 25348397 | N/A | physical interaction | ComPPI |
| WDR81 | UTP4 | 22916032 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |