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GENE：CHUK

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CHUK
FullNmae component of inhibitor of nuclear factor kappa B kinase complex
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1974
EnsembleID ENSG00000213341
Uniprot O15111

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CHUK necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CHUK immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CHUK autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CHUK apoptosis 34474146 In the present study, conserved helix-loop-helix ubiquitous kinase (CHUK) overexpression accelerated proliferation and suppressed apoptosis of MCL cells after ibrutinib treatment in vitro. retulator signature
CHUK alkaliptosis 39937414 In the alkaliptosis gene set (IKBKB, NFKB1, CA9, CHUK, IKBKG, and RELA), NFKB1, CHUK, and IKBKG exhibited differential expression in TCGA-KIRC. retulator signature
CHUK alkaliptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
CHUK GO:0003009,GO:0004672,GO:0004674,GO:0005515,GO:0005524,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0006468,GO:0006954,GO:0006955,GO:0007249,GO:0007249,GO:0007249,GO:0007252,GO:0007266,GO:0008384,GO:0008384,GO:0008384,GO:0008385,GO:0008385,GO:0009410,GO:0009615,GO:0009636,GO:0009653,GO:0009898,GO:0010034,GO:0018105,GO:0032088,GO:0032496,GO:0032727,GO:0033194,GO:0033209,GO:0034142,GO:0034614,GO:0035631,GO:0038061,GO:0038061,GO:0042803,GO:0043123,GO:0043200,GO:0044877,GO:0045087,GO:0045893,GO:0045944,GO:0045944,GO:0046982,GO:0051092,GO:0051092,GO:0051146,GO:0061847,GO:0071276,GO:0071356,GO:0097110,GO:0098586,GO:1990459

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CHUK hsa:1147 path:hsa01523 Antifolate resistance - Homo sapiens (human)
CHUK hsa:1147 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04068 FoxO signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04210 Apoptosis - Homo sapiens (human)
CHUK hsa:1147 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)
CHUK hsa:1147 path:hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04657 IL-17 signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human)
CHUK hsa:1147 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
CHUK hsa:1147 path:hsa04660 T cell receptor signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04662 B cell receptor signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04668 TNF signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04920 Adipocytokine signaling pathway - Homo sapiens (human)
CHUK hsa:1147 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
CHUK hsa:1147 path:hsa05010 Alzheimer disease - Homo sapiens (human)
CHUK hsa:1147 path:hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
CHUK hsa:1147 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
CHUK hsa:1147 path:hsa05131 Shigellosis - Homo sapiens (human)
CHUK hsa:1147 path:hsa05132 Salmonella infection - Homo sapiens (human)
CHUK hsa:1147 path:hsa05135 Yersinia infection - Homo sapiens (human)
CHUK hsa:1147 path:hsa05142 Chagas disease - Homo sapiens (human)
CHUK hsa:1147 path:hsa05145 Toxoplasmosis - Homo sapiens (human)
CHUK hsa:1147 path:hsa05160 Hepatitis C - Homo sapiens (human)
CHUK hsa:1147 path:hsa05161 Hepatitis B - Homo sapiens (human)
CHUK hsa:1147 path:hsa05162 Measles - Homo sapiens (human)
CHUK hsa:1147 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
CHUK hsa:1147 path:hsa05164 Influenza A - Homo sapiens (human)
CHUK hsa:1147 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
CHUK hsa:1147 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
CHUK hsa:1147 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
CHUK hsa:1147 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
CHUK hsa:1147 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
CHUK hsa:1147 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
CHUK hsa:1147 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
CHUK hsa:1147 path:hsa05200 Pathways in cancer - Homo sapiens (human)
CHUK hsa:1147 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
CHUK hsa:1147 path:hsa05212 Pancreatic cancer - Homo sapiens (human)
CHUK hsa:1147 path:hsa05215 Prostate cancer - Homo sapiens (human)
CHUK hsa:1147 path:hsa05220 Chronic myeloid leukemia - Homo sapiens (human)
CHUK hsa:1147 path:hsa05221 Acute myeloid leukemia - Homo sapiens (human)
CHUK hsa:1147 path:hsa05222 Small cell lung cancer - Homo sapiens (human)
CHUK hsa:1147 path:hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human)
CHUK hsa:1147 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)
CHUK hsa:1147 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IKBKG CHUK 10968790 11340079 11877453 12133805 12799363 14743216 15084594 15199157 15485931 16818229 17363905 17485448 17693255 17702576 18716620 20098747 20138012 20300203 20531300 21217011 22435554 23109003 23180781 23430059 24369075 26192618 28462531 interaction type,physical association,chemical activation reaction affinity chromatography technology,anti tag coimmunoprecipitation,gst pull down,protein array ACSN,InnateDB,SignaLink
CHUK IKBKB 12799363 15456791 18949366 21903422 23180781 23430059 26192618 association,physical association affinity chromatography technology,anti tag coimmunoprecipitation ACSN,InnateDB
SDHC CHUK 12799363 23430059 26192618 association N/A ACSN
CHUK APC 11955436 11967263 12051714 12799363 23430059 26192618 7542250 8666229 interaction type N/A ACSN
CHUK AXIN1 11955436 11967263 12051714 12799363 23430059 26192618 7542250 8666229 interaction type N/A ACSN
CHUK NFKBIA 10593898 12799363 15084594 23109003 23430059 26192618 29145629 9135156 9315679 9721103 9914500 interaction type,enzymatic reaction,chemical activation reaction inferred by curator ACSN,Reactome,SignaLink
MCL1 CHUK 11274345 12847084 15592525 17462996 18641653 19392652 19509052 21133840 21232017 23430059 23850759 24378531 26192618 26587781 interaction type N/A ACSN
TRAF2 CHUK 10795740 11274345 12847084 15592525 17462996 18641653 19150425 19392652 19509052 21133840 21232017 23180781 23430059 23850759 24378531 26192618 26587781 interaction type,physical association anti tag coimmunoprecipitation,fluorescent resonance energy transfer ACSN,InnateDB
MAP3K14 CHUK 10072079 10713178 11278268 15994789 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
MAP3K11 CHUK 10713178 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
AKT1 CHUK 10485710 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,protein kinase assay InnateDB
AKT2 CHUK 12048203 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
MAP3K1 CHUK 10713178 23180781 phosphorylation reaction in-gel kinase assay InnateDB
IKBKB CHUK 10893415 11242109 11325957 11460167 11971985 12221085 12351658 14514672 14695475 15145317 15229184 15456791 16115877 16301747 17047224 17496917 17728323 18462684 19666475 19909372 20300203 20434986 20449947 21903422 23180781 24100029 24369075 29145629 9008162 9689078 9721103 9744859 9751060 9891086 physical association anti tag coimmunoprecipitation,inferred by curator InnateDB,Reactome
MAP3K8 CHUK 10072079 23180781 physical association anti tag coimmunoprecipitation InnateDB
CTNNB1 CHUK 11527961 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,gst pull down,in-gel kinase assay InnateDB
NFKBIA CHUK 10074115 10085062 10469655 10527519 11527961 11809792 12626540 12637324 15856023 15922746 16023083 16737960 23180781 9891086 phosphorylation reaction anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
NFKB1 CHUK 10469655 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
IRS1 CHUK 12351658 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
PRKCQ CHUK 11120819 23180781 physical association anti tag coimmunoprecipitation InnateDB
BIRC3 CHUK 15494311 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 CHUK 15494311 23180781 physical association anti tag coimmunoprecipitation InnateDB
CASP8 CHUK 11002417 23180781 physical association anti tag coimmunoprecipitation InnateDB
FANCA CHUK 12210728 23180781 physical association anti tag coimmunoprecipitation InnateDB
TNFRSF1A CHUK 10755617 10795740 23180781 23815148 24323043 physical association anti tag coimmunoprecipitation InnateDB
TNFAIP3 CHUK 11594795 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRPC4AP CHUK 14585990 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
PPM1B CHUK 14585847 23180781 physical association anti tag coimmunoprecipitation,dephosphorylation reaction InnateDB
HSPB1 CHUK 16840786 23180781 physical association anti tag coimmunoprecipitation InnateDB
HSPD1 CHUK 16840786 23180781 physical association anti tag coimmunoprecipitation InnateDB
HSPA1B CHUK 16840786 23180781 physical association anti tag coimmunoprecipitation InnateDB
HSP90AA1 CHUK 16840786 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRIO CHUK 17292329 23180781 physical association anti tag coimmunoprecipitation InnateDB
CSF2RA CHUK 12637324 23180781 physical association anti tag coimmunoprecipitation InnateDB
CREBBP CHUK 14597638 23180781 physical association gst pull down InnateDB
PRKRA CHUK 11313968 23180781 physical association anti tag coimmunoprecipitation InnateDB
VAV1 CHUK 12626540 23180781 physical association anti tag coimmunoprecipitation InnateDB
CCND1 CHUK 15808510 23180781 physical association anti tag coimmunoprecipitation InnateDB
MYC CHUK 15808510 23180781 physical association anti tag coimmunoprecipitation InnateDB
EBAG9 CHUK 15808510 23180781 physical association anti tag coimmunoprecipitation InnateDB
ESR1 CHUK 15808510 23180781 physical association anti tag coimmunoprecipitation InnateDB
NCOA3 CHUK 11971985 15808510 23180781 physical association anti tag coimmunoprecipitation InnateDB
CHUK CCND1 15808510 23180781 physical association anti tag coimmunoprecipitation InnateDB
CHUK NCOA3 15808510 23180781 physical association anti tag coimmunoprecipitation InnateDB
CHUK ESR1 15808510 23180781 physical association anti tag coimmunoprecipitation InnateDB
ETS1 CHUK 15469934 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
FOXO3 CHUK 15084260 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,gst pull down,in-gel kinase assay InnateDB
H3-3A CHUK 17643371 23180781 physical association gst pull down InnateDB
ARRB2 CHUK 15173580 23180781 physical association anti tag coimmunoprecipitation InnateDB
ARRB1 CHUK 15173580 23180781 physical association anti tag coimmunoprecipitation InnateDB
DNAJA3 CHUK 15601829 23180781 physical association gst pull down InnateDB
EIF2AK2 CHUK 10723127 23180781 physical association anti tag coimmunoprecipitation InnateDB
NLRP2 CHUK 15456791 23180781 physical association anti tag coimmunoprecipitation InnateDB
CHUK NLRP2 15456791 23180781 physical association anti tag coimmunoprecipitation InnateDB
PYCARD CHUK 12486103 23180781 physical association anti tag coimmunoprecipitation InnateDB
PYDC1 CHUK 12656673 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAVS CHUK 18550535 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRAK1 CHUK 18180283 23180781 physical association anti tag coimmunoprecipitation InnateDB
LTBR CHUK 15743811 23180781 physical association anti tag coimmunoprecipitation InnateDB
MTOR CHUK 18490760 18519641 23180781 physical association anti tag coimmunoprecipitation InnateDB
CHUK TNF 19287455 23180781 physical association pull down InnateDB
ELP1 CHUK 10094049 23180781 9751059 physical association anti tag coimmunoprecipitation InnateDB
TANK CHUK 12133833 23180781 physical association anti tag coimmunoprecipitation InnateDB
PPP1CA CHUK 18949366 23180781 physical association anti tag coimmunoprecipitation InnateDB
CHUK RIPK1 18949366 23180781 24323043 physical association affinity chromatography technology,anti tag coimmunoprecipitation InnateDB
CHUK PPP1CA 18949366 23180781 physical association affinity chromatography technology InnateDB
CHUK MAP3K7 11325957 11460167 14514672 16301747 16356855 17047224 17496917 18949366 19909372 20300203 23180781 29145629 9744859 enzymatic reaction,physical association affinity chromatography technology,inferred by curator InnateDB,Reactome
NOTCH1 CHUK 18560356 23180781 23331499 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink
MLST8 CHUK 18755269 23180781 physical association anti tag coimmunoprecipitation InnateDB
CHUK MAP3K1 18182252 23180781 physical association anti tag coimmunoprecipitation InnateDB
CHUK MAP2K4 18182252 23180781 physical association anti tag coimmunoprecipitation InnateDB
CUEDC2 CHUK 18362886 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRIM27 CHUK 16393995 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
RELA CHUK 12665576 23180781 physical association anti tag coimmunoprecipitation InnateDB
NLRC5 CHUK 20434986 23180781 physical association anti tag coimmunoprecipitation InnateDB
TBK1 CHUK 21138416 23180781 phosphorylation reaction in-gel kinase assay InnateDB
CHUK CHUK 20501937 21399639 23180781 24243840 26467481 29145629 phosphorylation reaction,physical association,down-regulates quantity by destabilization inferred by curator,protein kinase assay InnateDB,Reactome,Signor
BID CHUK 21552281 23180781 physical association anti tag coimmunoprecipitation InnateDB
NLRX1 CHUK 21703539 23180781 physical association anti tag coimmunoprecipitation InnateDB
CHUK CDC37 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
CHUK RELA 10593898 21903422 23180781 24129565 29145629 9135156 9315679 9721103 9914500 enzymatic reaction,physical association anti tag coimmunoprecipitation,inferred by curator InnateDB,Reactome
IKBKE CHUK 21138416 23180781 phosphorylation reaction in-gel kinase assay,protein kinase assay InnateDB
CHUK TRAF2 23180781 24323043 physical association anti tag coimmunoprecipitation InnateDB
CHUK RACK1 23180781 24323043 physical association anti tag coimmunoprecipitation InnateDB
RACK1 CHUK 23180781 24323043 physical association anti tag coimmunoprecipitation,pull down InnateDB
SASH1 CHUK 23180781 23776175 physical association anti tag coimmunoprecipitation InnateDB
SRPK1 CHUK 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB
SRPK2 CHUK 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB
CHUK IKBKG 10893415 11325957 11460167 12221085 14514672 14695475 15145317 16115877 16301747 17047224 17496917 17728323 18462684 19666475 19909372 20300203 20434986 20449947 24369075 29145629 9008162 9689078 9744859 9751060 physical association inferred by curator Reactome
CHUK BTRC 15340381 16303288 29145629 8706131 9346238 physical association inferred by curator Reactome
CHUK FBXW11 15340381 16303288 29145629 8706131 9346238 physical association inferred by curator Reactome
CHUK CUL1 15340381 16303288 29145629 8706131 9346238 physical association inferred by curator Reactome
CHUK SKP1 15340381 16303288 29145629 8706131 9346238 physical association inferred by curator Reactome
CHUK BCL10 16301747 16356855 19909372 29145629 physical association inferred by curator Reactome
CHUK CARD11 16301747 16356855 19909372 29145629 physical association inferred by curator Reactome
CHUK MALT1 16301747 16356855 19909372 29145629 physical association inferred by curator Reactome
NFKBIE CHUK 10593898 29145629 9135156 9315679 9721103 9914500 enzymatic reaction inferred by curator Reactome
CHUK REL 10593898 29145629 9135156 9315679 9721103 9914500 enzymatic reaction inferred by curator Reactome
CHUK NFKBIB 10593898 15084594 23109003 29145629 9135156 9315679 9721103 9914500 enzymatic reaction,chemical activation reaction inferred by curator Reactome,SignaLink
CHUK NFKB1 10593898 29145629 9135156 9315679 9721103 9914500 enzymatic reaction inferred by curator Reactome

Source Target Pmid Interactiontype Methods Database
BCL10 CHUK 20005715 interaction type N/A PSP
IRS1 CHUK 20005715 interaction type N/A PSP
NFKBIA CHUK 20005715 interaction type N/A PSP
NFKBIB CHUK 20005715 interaction type N/A PSP
TANK CHUK 20005715 interaction type N/A PSP
TRAF2 CHUK 20005715 interaction type N/A PSP
TRAF3IP2 CHUK 20005715 interaction type N/A PSP
MAVS CHUK 20005715 interaction type N/A PSP
NFKBIA CHUK 10066434 11042193 11095741 11809792 12054687 15389589 18501560 18988627 20005715 20932476 21071413 9244310 9252186 9346485 N/A N/A SignaLink
NFKBIB CHUK 18988627 20005715 21071413 9252186 9346485 9689078 N/A N/A SignaLink
IRS1 CHUK 12351658 12351658 18988627 20005715 20005715 21071413 N/A N/A SignaLink
BCL10 CHUK 11113112 18988627 20005715 20005715 N/A N/A SignaLink
TANK CHUK 20005715 20005715 N/A N/A SignaLink
TRAF2 CHUK 11359906 18988627 20005715 20005715 21071413 9244310 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 CHUK 15469934 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
YBX1 CHUK 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CHUK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CHUK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CHUK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CHUK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CHUK 15469934 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000171CD1 CHUK 20711193 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000040EE1D CHUK 23487264 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000B7E30 CHUK 20711193 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000183BED CHUK 22660635 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000171CD1 CHUK 20711193 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000B7E30 CHUK 20711193 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000183BED CHUK 22660635 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000040EE1D CHUK 23487264 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000122ED0 CHUK 25416803 25623956 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00001CC864 CHUK 25416803 27537390 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CHUK NCOA3 22135298 phosphorylation N/A PhosphoSite
CHUK NFKB1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CHUK ESR1 22135298 phosphorylation N/A PhosphoSite
CHUK TRAF4 22135298 phosphorylation N/A PhosphoSite
CHUK NFKBIA 22135298 phosphorylation N/A PhosphoSite
CHUK FOXA2 22135298 phosphorylation N/A PhosphoSite
CHUK NFKB2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CHUK RELB 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CHUK ATG16L1 22135298 phosphorylation N/A PhosphoSite
CHUK CTNNB1 22135298 phosphorylation N/A PhosphoSite
CHUK CREBBP 22135298 phosphorylation N/A PhosphoSite
CHUK MTOR 22135298 phosphorylation N/A PhosphoSite
CHUK NCOR2 22135298 phosphorylation N/A PhosphoSite
CHUK BBC3 22135298 phosphorylation N/A PhosphoSite
CHUK RELA 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CHUK ELAVL1 22135298 phosphorylation N/A PhosphoSite
CHUK CCND1 22135298 phosphorylation N/A PhosphoSite
CHUK FOXO3 22135298 phosphorylation N/A PhosphoSite
CHUK REL 22135298 phosphorylation N/A PhosphoSite
MAP3K14 CHUK 22135298 phosphorylation N/A PhosphoSite
AKT2 CHUK 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
AKT1 CHUK 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
IRAK1 CHUK 25361965 interaction type N/A PTMCode2
CHUK IRAK1 25361965 interaction type N/A PTMCode2
CNTN2 CHUK 25361965 interaction type N/A PTMCode2
CHUK CNTN2 25361965 interaction type N/A PTMCode2
CDC37 CHUK 25361965 interaction type N/A PTMCode2
CHUK CDC37 25361965 interaction type N/A PTMCode2
NLRP4 CHUK 25361965 interaction type N/A PTMCode2
CHUK NLRP4 25361965 interaction type N/A PTMCode2
TANK CHUK 25361965 interaction type N/A PTMCode2
CHUK TANK 25361965 interaction type N/A PTMCode2
PRKCI CHUK 25361965 interaction type N/A PTMCode2
CHUK PRKCI 25361965 interaction type N/A PTMCode2
PRKCQ CHUK 25361965 interaction type N/A PTMCode2
CHUK PRKCQ 25361965 interaction type N/A PTMCode2
IRF7 CHUK 25361965 interaction type N/A PTMCode2
CHUK IRF7 25361965 interaction type N/A PTMCode2
TNFAIP3 CHUK 25361965 interaction type N/A PTMCode2
CHUK TNFAIP3 25361965 interaction type N/A PTMCode2
EIF2AK2 CHUK 25361965 interaction type N/A PTMCode2
CHUK EIF2AK2 25361965 interaction type N/A PTMCode2
TP53 CHUK 25361965 interaction type N/A PTMCode2
CHUK TP53 25361965 interaction type N/A PTMCode2
NFKBIB CHUK 25361965 interaction type N/A PTMCode2
CHUK NFKBIB 25361965 interaction type N/A PTMCode2
BCL10 CHUK 25361965 interaction type N/A PTMCode2
CHUK BCL10 25361965 interaction type N/A PTMCode2
SRC CHUK 25361965 interaction type N/A PTMCode2
CHUK SRC 25361965 interaction type N/A PTMCode2
MAP3K8 CHUK 25361965 interaction type N/A PTMCode2
CHUK MAP3K8 25361965 interaction type N/A PTMCode2
CHUK FANCA 25361965 interaction type N/A PTMCode2
FANCA CHUK 25361965 interaction type N/A PTMCode2
CHUK AKT2 25361965 interaction type N/A PTMCode2
CHUK MAP3K1 25361965 interaction type N/A PTMCode2
MAP3K1 CHUK 25361965 interaction type N/A PTMCode2
RELA CHUK 25361965 interaction type N/A PTMCode2
IRS1 CHUK 25361965 interaction type N/A PTMCode2
CHUK IRS1 25361965 interaction type N/A PTMCode2
CHUK AKT1 25361965 interaction type N/A PTMCode2
NFKB2 CHUK 25361965 interaction type N/A PTMCode2
RELB CHUK 25361965 interaction type N/A PTMCode2
IKBKG CHUK 25361965 interaction type N/A PTMCode2
CHUK IKBKG 25361965 interaction type N/A PTMCode2
MAP3K3 CHUK 25361965 interaction type N/A PTMCode2
CHUK MAP3K3 25361965 interaction type N/A PTMCode2
HSP90AA1 CHUK 25361965 interaction type N/A PTMCode2
CHUK HSP90AA1 25361965 interaction type N/A PTMCode2
NFKB1 CHUK 25361965 interaction type N/A PTMCode2
CASP8 CHUK 25361965 interaction type N/A PTMCode2
CHUK CASP8 25361965 interaction type N/A PTMCode2
TNFRSF1A CHUK 25361965 interaction type N/A PTMCode2
CHUK TNFRSF1A 25361965 interaction type N/A PTMCode2
NFKBIE CHUK 25361965 interaction type N/A PTMCode2
CHUK NFKBIE 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2I CHUK 25348397 N/A physical interaction ComPPI
CDC73 CHUK 25348397 N/A physical interaction ComPPI
TNFAIP3 CHUK 11594795 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ACTG1 CHUK 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUBB CHUK 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CDKN1B CHUK 23602409 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
TRAF6 CHUK 25348397 N/A physical interaction ComPPI
CALM1 CHUK 25348397 N/A tandem affinity purification ComPPI
KEAP1 CHUK 20600852 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMN1 CHUK 25348397 N/A physical interaction ComPPI
HSP90AB1 CHUK 14525934 14743216 24234451 25348397 physical association experimental interaction detection,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
UBE2E3 CHUK 14525934 25348397 9409737 N/A two hybrid,two hybrid ComPPI,HPRD
EGLN3 CHUK 25348397 N/A physical interaction ComPPI
ERBIN CHUK 25348397 N/A physical interaction ComPPI
PRKCQ CHUK 14525934 15802604 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PTPN11 CHUK 11136824 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PRKCA CHUK 25348397 N/A physical interaction ComPPI
SRC CHUK 12707358 14525934 15749833 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PRKCD CHUK 25348397 N/A physical interaction ComPPI
PRKDC CHUK 14525934 25348397 9632806 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CREBBP CHUK 11971985 12789342 14525934 24234451 25348397 association affinity chromatography technology,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
SMAD2 CHUK 18268325 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
NCOA3 CHUK 11971985 14525934 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
EP300 CHUK 25348397 N/A physical interaction ComPPI
SMAD3 CHUK 18268325 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
COPS5 CHUK 25348397 N/A physical interaction ComPPI
PIAS1 CHUK 14525934 17540171 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
GLI1 CHUK 25348397 N/A physical interaction ComPPI
CLU CHUK 25348397 N/A physical interaction ComPPI
NCOR2 CHUK 25348397 N/A physical interaction,in vitro ComPPI
NCOR1 CHUK 25348397 N/A physical interaction ComPPI
CSF2RA CHUK 12637324 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
UBC CHUK 25348397 N/A physical interaction ComPPI
HSP90AA1 CHUK 11864612 14525934 14743216 19875381 24234451 25348397 association,physical association experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
UBE2N CHUK 25348397 N/A physical interaction ComPPI
NTRK1 CHUK 25348397 N/A physical interaction ComPPI
BTRC CHUK 25348397 N/A physical interaction ComPPI
EIF2AK2 CHUK 10648614 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CASP8 CHUK 11002417 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
IKBKB CHUK 11971985 12486103 14525934 14743216 16129692 16286467 16319058 20434986 21903422 24234451 25241761 25348397 25852190 9751060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,tandem affinity purification,proximity ligation assay ComPPI,HPRD,IntAct
PPP1CA CHUK 25348397 N/A physical interaction ComPPI
MYC CHUK 21575199 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
MAP3K4 CHUK 25348397 N/A physical interaction ComPPI
PEBP1 CHUK 11585904 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PRKCB CHUK 12070292 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
TNFRSF1A CHUK 10755617 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
NFKBIA CHUK 10733566 11042193 11095741 11809792 12486103 12730857 14525934 14743216 15389589 16286467 18922877 21765415 23602409 24234451 25348397 9244310 9252186 9520446 phosphorylation reaction,physical association experimental interaction detection,physical interaction,protein kinase assay,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CSNK2A1 CHUK 25348397 N/A physical interaction ComPPI
CAPZA1 CHUK 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
DUSP1 CHUK 25348397 N/A physical interaction ComPPI
CFTR CHUK 25348397 N/A physical interaction ComPPI
PPP2CA CHUK 16126728 24234451 25348397 association molecular sieving,physical interaction ComPPI,IntAct
TP73 CHUK 17452332 21482671 25348397 27898060 N/A physical interaction ComPPI,OmniPath
IRAK1 CHUK 25348397 N/A physical interaction ComPPI
TPM3 CHUK 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TNF CHUK 25348397 N/A physical interaction ComPPI
RELA CHUK 12842894 14525934 16046471 21903422 24234451 25348397 8246997 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
PKM CHUK 25348397 N/A protein kinase assay ComPPI
MAP3K11 CHUK 10713178 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ERC1 CHUK 25348397 N/A physical interaction ComPPI
XPO1 CHUK 25348397 N/A physical interaction ComPPI
TRAF1 CHUK 25348397 N/A physical interaction ComPPI
TRAF2 CHUK 11359906 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
NFKBIB CHUK 14525934 14743216 24234451 25348397 9252186 9689078 physical association experimental interaction detection,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
CLTC CHUK 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
SRPK1 CHUK 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
ARRB2 CHUK 17620599 24234451 25241761 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,proximity ligation assay ComPPI,IntAct
CHEK1 CHUK 14525934 17962807 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CUL1 CHUK 14525934 17914462 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
H3-4 CHUK 12789342 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
HTT CHUK 25348397 N/A physical interaction ComPPI
IRS1 CHUK 12351658 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
H3C15 CHUK 25348397 N/A physical interaction ComPPI
PRKCI CHUK 10848576 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
STAP2 CHUK 14525934 16365431 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
HSPB1 CHUK 25348397 N/A physical interaction ComPPI
CTNNB1 CHUK 11527961 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TP63 CHUK 25348397 N/A physical interaction ComPPI
CHUK MAP3K8 10072079 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CHUK MAP3K7 10094049 10187861 14525934 24234451 25241761 25348397 association,physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
CHUK ELP1 14525934 25348397 9751059 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CHUK CDC37 11864612 14525934 14743216 21903422 24189400 24234451 25036637 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CHUK TRAF3IP2 25348397 N/A physical interaction,in vivo ComPPI
CHUK TRPC4AP 14525934 14585990 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CHUK NLRP4 12093792 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CHUK ESR1 14525934 15808510 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CHUK FOXO3 14525934 15084260 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CHUK TANK 12133833 14525934 24234451 25348397 30561431 association experimental interaction detection,physical interaction,in vivo,virotrap ComPPI,HPRD,IntAct
CHUK NFKB2 14525934 14743216 18617892 24234451 25348397 physical association experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CHUK NR2C2 12547194 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CHUK NFKB1 11297557 11976329 12482991 14525934 24234451 25348397 25609649 phosphorylation reaction,association experimental interaction detection,physical interaction,protein kinase assay,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CHUK NOTCH3 14525934 17289033 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CHUK AKT1 10485710 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
CHUK AKT2 25348397 N/A physical interaction,in vitro,in vivo ComPPI
CHUK FANCA 25348397 N/A physical interaction ComPPI
CHUK PPM1B 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
CHUK IKBKG 10968790 12459277 12486103 14525934 14743216 15749833 16126728 16319058 16938294 17363973 17568778 18266467 19666608 20368414 20434986 21903422 24234451 24618592 25348397 26496610 30561431 9751060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,tandem affinity purification,virotrap ComPPI,HPRD,IntAct
CHUK CUEDC2 25348397 N/A physical interaction ComPPI
CHUK IRF5 25348397 N/A physical interaction ComPPI
CHUK TRIM40 25348397 N/A physical interaction ComPPI
CHUK TAB2 25348397 N/A physical interaction ComPPI
CHUK HSP90AA2P 25348397 N/A physical interaction ComPPI
CHUK IKBKE 25348397 N/A physical interaction ComPPI
CHUK MAP3K1 25348397 N/A physical interaction ComPPI
CHUK TNIP2 24234451 25348397 30561431 association physical interaction,virotrap ComPPI,IntAct
CHUK NLRP2 25348397 N/A physical interaction ComPPI
CHUK TRIM27 25348397 N/A physical interaction ComPPI
CHUK TNFRSF1B 25348397 N/A physical interaction ComPPI
CHUK TRADD 25348397 N/A physical interaction ComPPI
CHUK RIPK1 25348397 N/A physical interaction ComPPI
CHUK BCL2 25348397 N/A physical interaction ComPPI
CHUK MAGED1 25348397 N/A physical interaction ComPPI
CHUK CARD11 25348397 N/A physical interaction ComPPI
CHUK DHX40 25348397 N/A physical interaction ComPPI
CHUK DHX29 25348397 N/A physical interaction ComPPI
CHUK ELAVL1 25348397 N/A physical interaction ComPPI
CHUK PYCARD 12486103 24234451 25348397 colocalization,association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
CHUK NLRC5 20434986 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CHUK TRAF4 25348397 N/A physical interaction ComPPI
CHUK RIPK2 25348397 N/A physical interaction ComPPI
CHUK AURKA 17939994 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CHUK TPX2 17939994 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CHUK ATG16L2 25348397 N/A physical interaction ComPPI
CHUK COPS3 25348397 N/A physical interaction ComPPI
CHUK SASH1 25348397 N/A physical interaction ComPPI
CHUK RPL27 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CHUK PAX8 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CHUK SRPK2 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
CHUK MYH14 14743216 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
CHUK MYL12B 25348397 N/A physical interaction ComPPI
CHUK MYL12A 14743216 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
CHUK PAF1 25348397 N/A physical interaction ComPPI
CHUK STUB1 25348397 N/A physical interaction ComPPI
CHUK HNRNPA1 25348397 N/A physical interaction ComPPI
CHUK PSMD9 25348397 N/A physical interaction ComPPI
CHUK FKBP5 14525934 14743216 24234451 25036637 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,tandem affinity purification ComPPI,HPRD,IntAct
CHUK MTOR 25348397 N/A physical interaction ComPPI
CHUK RPTOR 25348397 N/A physical interaction ComPPI
CHUK TP53 11805286 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CHUK RICTOR 25348397 N/A physical interaction ComPPI
CHUK SHARPIN 21455180 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CHUK CD40 25348397 N/A physical interaction ComPPI
CHUK MAP3K3 14743216 24234451 25241761 25348397 physical association physical interaction,tandem affinity purification,proximity ligation assay ComPPI,IntAct
CHUK COMMD7 25348397 N/A physical interaction ComPPI
CHUK USP18 25348397 N/A physical interaction ComPPI
CHUK KLHL21 25348397 N/A physical interaction ComPPI
CHUK TRIM22 25348397 N/A physical interaction ComPPI
CHUK PSG1 25348397 N/A physical interaction ComPPI
CHUK INSYN2A 25348397 N/A physical interaction ComPPI
CHUK SHC4 25348397 N/A physical interaction ComPPI
CHUK BCL3 25348397 N/A physical interaction ComPPI
CHUK IFIT5 25348397 N/A physical interaction ComPPI
CHUK NFKBIE 14743216 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
CHUK MYH10 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CHUK TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CHUK MYH9 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CHUK MYL6 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CHUK TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CHUK MYO1D 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CHUK RELB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CHUK MAVS 16177806 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
CHUK TAX1BP1 21765415 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,protein kinase assay ComPPI,IntAct
CHUK IRF7 18922877 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
CHUK MAP3K21 24234451 25348397 26859459 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
HSPA9 CHUK 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MAP3K14 CHUK 10094049 14525934 14743216 16286467 16498412 24234451 25241761 25348397 9244310 9520446 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,protein kinase assay,in vivo,tandem affinity purification,proximity ligation assay ComPPI,HPRD,IntAct
BCL10 CHUK 11113112 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
EEF1A2 CHUK 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CHUK TGFBR1 14525934 15761153 N/A experimental interaction detection HPRD
CHUK CHUK 14525934 14743216 24234451 9520446 phosphorylation reaction,physical association experimental interaction detection,protein kinase assay,tandem affinity purification HPRD,IntAct
CALM2 CHUK 14743216 24234451 physical association tandem affinity purification IntAct
FADD CHUK 24234451 30561431 association virotrap IntAct
SRC CHUK 10485710 12707358 15749833 27898060 stimulant N/A OmniPath
CHUK CYLD 24614225 27898060 inhibition,stimulant N/A OmniPath
CHUK CTNNB1 11527961 12589056 17306568 17996206 18573912 21383695 25297629 27898060 N/A N/A OmniPath
CTNNB1 CHUK 11527961 12589056 27898060 N/A N/A OmniPath
CHUK TRIM27 16393995 27898060 N/A N/A OmniPath
TRIM27 CHUK 16393995 27898060 N/A N/A OmniPath
RACK1 CHUK 24323043 27898060 N/A N/A OmniPath
CHUK ATP2B1 2548572 27898060 N/A N/A OmniPath
ARRB2 CHUK 15173580 17620599 25241761 27898060 N/A N/A OmniPath
ARRB1 CHUK 15173580 27898060 N/A N/A OmniPath
CHUK MAP3K7 10094049 10187861 16893890 18949366 20200282 25241761 27898060 9742107 N/A N/A OmniPath
MAP3K7 CHUK 10094049 10187861 15836773 16893890 18949366 20200282 25241761 27898060 9742107 stimulant N/A OmniPath
CHUK TNFAIP3 11594795 27898060 N/A N/A OmniPath
TNFAIP3 CHUK 11594795 27898060 N/A N/A OmniPath
CHUK CSF2RA 12637324 27898060 N/A N/A OmniPath
CHUK MAP3K8 10072079 27898060 N/A N/A OmniPath
MAP3K8 CHUK 10072079 27898060 stimulant N/A OmniPath
TRAF2 CHUK 10795740 11359906 15725726 19150425 20449947 23007157 24323043 25241761 27898060 9244310 stimulant N/A OmniPath
CHUK H3-4 12789342 27898060 stimulant N/A OmniPath
ABL2 CHUK 21552281 27898060 N/A N/A OmniPath
CHUK EIF2AK2 10648614 10723127 10848580 27898060 N/A N/A OmniPath
HSPD1 CHUK 16840786 27898060 N/A N/A OmniPath
CHUK PYCARD 12486103 27898060 N/A N/A OmniPath
PYCARD CHUK 12486103 27898060 N/A N/A OmniPath
CHUK IKBKE 21138416 27898060 N/A N/A OmniPath
CHUK ELAVL1 23115237 27898060 N/A N/A OmniPath
MYC CHUK 15808510 21575199 27898060 N/A N/A OmniPath
CHUK MAP3K14 10072079 10094049 10713178 10887201 11278268 14743216 15084608 15208311 15994789 16286467 16498412 17563756 20348096 20501937 20651737 25241761 27898060 9244310 9520446 inhibition N/A OmniPath
MAP3K14 CHUK 10072079 10094049 10713178 10887201 11278268 11520989 14743216 15084608 15140882 15208311 15994789 16223731 16286467 16498412 17563756 18515365 20348096 20501937 20651737 25241761 27898060 9020361 9244310 9346485 9520446 9742107 stimulant N/A OmniPath
CHUK FOXO3 15084260 27898060 inhibition N/A OmniPath
CHUK MAP3K1 10713178 16286467 18182252 27898060 9689078 9819420 N/A N/A OmniPath
MAP3K1 CHUK 10713178 16286467 18182252 27898060 9689078 9819420 stimulant N/A OmniPath
CHUK NCOA3 11971985 15302935 15383283 15808510 16051665 16135815 16964243 18669648 18922467 19413330 19651622 20068231 22505454 27898060 stimulant N/A OmniPath
NCOA3 CHUK 11971985 15383283 15808510 16051665 27898060 N/A N/A OmniPath
CHUK NCOR2 15494311 16382138 16846590 27898060 inhibition N/A OmniPath
CHUK TNFRSF1B 27898060 9535738 N/A N/A OmniPath
CHUK NFKB1 10469655 11158290 11976329 12482991 14743216 15494311 16382138 19442713 27898060 8522173 inhibition,stimulant N/A OmniPath
CHUK HDAC3 15494311 16382138 27898060 N/A N/A OmniPath
CHUK ESR1 12093745 12466266 14764652 14977836 15355923 15461668 15784730 15808510 15831449 15913882 15919818 16223974 17047081 17384676 17466625 19940281 20103631 20696772 27898060 7476978 7491495 N/A N/A OmniPath
CHUK MAVS 16153868 16177806 17468758 18550535 27898060 N/A N/A OmniPath
MLST8 CHUK 18755269 27898060 N/A N/A OmniPath
CHUK AKT1 10485710 10485711 15800029 19609947 25241761 27898060 N/A N/A OmniPath
AKT1 CHUK 10485710 10485711 12048203 15800029 19088076 19442713 19609947 25241761 27898060 stimulant N/A OmniPath
CHUK IRS1 12351658 27898060 inhibition N/A OmniPath
CHUK H3C1 16916935 27898060 N/A N/A OmniPath
CHUK REL 17072339 27898060 N/A N/A OmniPath
CHUK IKBKG 10733566 10748240 10837071 10968790 10980203 11057907 11080499 11485410 11864612 11865184 11877453 12070292 12138192 12244103 12459277 12486103 12612076 12808104 14743216 15184390 15214841 15218526 15749833 15836773 16126728 16285893 16319058 16497931 16583354 16611882 16938294 16970925 17000764 17072322 17244613 17363973 17561400 17568778 17702576 17728323 17977820 18079694 18207244 18266467 18949366 19666608 19815509 19959994 20098747 20368414 21455180 21703539 21903422 22547678 22605335 22990857 23131831 23871670 23986494 24240172 24369075 24469399 24618592 25304104 26496610 27898060 9751060 N/A N/A OmniPath
IKBKG CHUK 10733566 10748240 10837071 10968790 10980203 11057907 11080499 11485410 11864612 11865184 11877453 12070292 12138192 12244103 12459277 12486103 12612076 12808104 14743216 15184390 15214841 15218526 15749833 15836773 16126728 16285893 16319058 16497931 16583354 16611882 16938294 16970925 17000764 17072322 17244613 17363973 17561400 17568778 17702576 17728323 17977820 18079694 18207244 18266467 18949366 19666608 19815509 19959994 20098747 20368414 21455180 21703539 21903422 22547678 22605335 22990857 23131831 23871670 23986494 24240172 24369075 24469399 24618592 25304104 26496610 27898060 9751060 N/A N/A OmniPath
PRKCQ CHUK 11120819 15802604 17363905 20164171 27898060 stimulant N/A OmniPath
FANCA CHUK 12210728 14499622 27898060 N/A N/A OmniPath
CHUK CREBBP 12789342 14597638 17434128 27898060 stimulant N/A OmniPath
CREBBP CHUK 12789342 14597638 17434128 27898060 N/A N/A OmniPath
CHUK CASP8 11002417 27898060 N/A N/A OmniPath
CHUK NFKBIA 10074115 10085062 10094049 10195894 10329646 10329681 10469655 10527519 10602462 10723801 10733566 10880512 10882136 11042193 11080499 11087742 11095741 11113112 11527961 11809792 11940602 12054687 12138192 12190313 12411322 12486103 12514169 12626540 12637324 14743216 15145317 15310755 15371334 15389589 15590691 15670770 15836773 15856023 15922746 16023083 16153868 16177806 16286467 16319058 16354686 16493424 16737960 16965765 17053167 17363905 17379600 17384642 17468758 17706453 17965022 18003900 18074035 18501560 18519641 18922877 18949366 19959994 20133937 20434986 20449947 20932476 21765415 23602409 24270572 24618592 26186194 27898060 7739562 7796813 7862124 7878466 8657102 9244310 9252186 9346241 9346485 9520446 9689078 9721103 9751059 9891086 9914500 inhibition,stimulant N/A OmniPath
LTBR CHUK 15743811 27898060 N/A N/A OmniPath
TNF CHUK 19287455 27898060 stimulant N/A OmniPath
CHUK PPP1CA 18949366 27898060 N/A N/A OmniPath
CHUK RELA 10521409 12842894 15489227 15494311 15611276 16046471 16382138 16846590 17434128 18519641 21903422 24129565 27898060 8246997 stimulant N/A OmniPath
RELA CHUK 12842894 15489227 16046471 16382138 17434128 18519641 21903422 24129565 27898060 8246997 N/A N/A OmniPath
CHUK TSC2 18490760 27898060 inhibition N/A OmniPath
CHUK IRF7 16612387 18922877 27898060 stimulant N/A OmniPath
AKT3 CHUK 19609947 27898060 stimulant N/A OmniPath
SGK1 CHUK 19088076 27898060 N/A N/A OmniPath
CHUK NOTCH1 18560356 27898060 N/A N/A OmniPath
NOTCH1 CHUK 18560356 27898060 stimulant N/A OmniPath
CHUK TRAF4 22547678 27898060 inhibition N/A OmniPath
PPP2CA CHUK 16126728 27898060 9252186 N/A N/A OmniPath
CHUK PIAS1 17540171 23032264 27898060 N/A N/A OmniPath
CHUK CCND1 16103118 27898060 8058338 inhibition,stimulant N/A OmniPath
CHUK RIPK1 18949366 24323043 27898060 N/A N/A OmniPath
CHUK TNFRSF1A 10755617 10795740 18949366 21724995 23815148 24323043 27898060 N/A N/A OmniPath
TNFRSF1A CHUK 10755617 10795740 18949366 21724995 23815148 24323043 27898060 stimulant N/A OmniPath
TBK1 CHUK 21138416 27898060 N/A N/A OmniPath
CHUK AKT2 12048203 19609947 27898060 N/A N/A OmniPath
AKT2 CHUK 12048203 19609947 27898060 stimulant N/A OmniPath
CHUK PRKRA 11313968 27898060 N/A N/A OmniPath
CHUK NFKBIB 10593965 10723801 11485410 14743216 15145317 15836773 16260493 17072322 22351927 27898060 8657102 9252186 9346485 9689078 stimulant N/A OmniPath
CHUK MTOR 18490760 18519641 27898060 N/A N/A OmniPath
MTOR CHUK 18490760 18519641 27898060 N/A N/A OmniPath
CHUK NFKB2 11239468 11520989 12387745 14743216 15084608 15140882 15145317 15214841 15218526 15310758 15371334 16285893 16303288 16651533 16793322 16970925 17072322 17561400 17563756 18617892 27898060 inhibition,stimulant N/A OmniPath
HSPB1 CHUK 16840786 27898060 N/A N/A OmniPath
IRAK1 CHUK 11096118 18180283 27898060 stimulant N/A OmniPath
IKBKB CHUK 10094049 10195894 10733566 10837071 10968790 11057907 11080499 11585904 11864612 11971985 12070292 12210728 12244103 12351658 12486103 14743216 15214841 15218526 15327770 15456791 15620648 15691841 16129692 16186825 16260493 16285893 16286467 16319058 16493424 16970925 17072322 17561400 17693255 17965022 18949366 20932476 21575199 21784860 21903422 24240172 25241761 25748427 25852190 27898060 9346241 9346484 9346485 9721103 9751060 9891086 9914500 stimulant N/A OmniPath
CHUK IKBKB 10022904 10094049 10195894 10733566 10779355 10837071 10968790 11057907 11080499 11585904 11864612 11971985 12070292 12210728 12244103 12351658 12486103 14743216 15214841 15218526 15327770 15456791 15620648 15691841 16129692 16186825 16260493 16285893 16286467 16319058 16493424 16970925 17072322 17561400 17693255 17965022 18949366 20932476 21575199 21784860 21903422 24240172 25241761 25748427 25852190 27898060 9346241 9346484 9346485 9689078 9721103 9751060 9891086 9914500 N/A N/A OmniPath
NLRC5 CHUK 20434986 27898060 N/A N/A OmniPath
TANK CHUK 12133833 27898060 N/A N/A OmniPath
ELP1 CHUK 10094049 27898060 9751059 N/A N/A OmniPath
CHUK H3-3A 12588998 17643371 27898060 stimulant N/A OmniPath
CHUK TRPC4AP 14585990 27898060 N/A N/A OmniPath
TRPC4AP CHUK 14585990 27898060 N/A N/A OmniPath
ERC1 CHUK 15218148 15218526 15371334 16497931 16970925 17072322 27898060 stimulant N/A OmniPath
CHUK NLRX1 21703539 27898060 N/A N/A OmniPath
CHUK VAV1 12626540 27898060 N/A N/A OmniPath
CHUK PPM1B 14585847 25241761 27898060 N/A N/A OmniPath
PPM1B CHUK 14585847 25241761 27898060 N/A N/A OmniPath
CHUK TAX1BP1 21765415 27898060 stimulant N/A OmniPath
CUEDC2 CHUK 18362886 27898060 N/A N/A OmniPath
SASH1 CHUK 23776175 27898060 N/A N/A OmniPath
DNAJA3 CHUK 15601829 27898060 N/A N/A OmniPath
PYDC1 CHUK 12656673 27898060 N/A N/A OmniPath
CHUK TRIO 17292329 27898060 N/A N/A OmniPath
CHUK MAP3K11 10713178 27898060 N/A N/A OmniPath
CHUK NLRP2 15456791 27898060 N/A N/A OmniPath
NLRP2 CHUK 15456791 27898060 N/A N/A OmniPath
CDC37 CHUK 11864612 14743216 16970925 17072322 21903422 24189400 25036637 27898060 N/A N/A OmniPath
CHUK RAB4A 1425574 27898060 N/A N/A OmniPath
CHUK FOXA2 22196886 27898060 inhibition N/A OmniPath
PPP2CB CHUK 27898060 9252186 N/A N/A OmniPath
CHUK LMNB1 2188730 27898060 N/A N/A OmniPath

Visualization










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