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GENE：FASLG

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FASLG
FullNmae Fas ligand
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11936
EnsembleID ENSG00000117560
Uniprot P48023

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FASLG necroptosis 35775116 We recently found that injured muscle fibres in PM undergo FASLG-mediated necroptosis, a form of regulated cell death accompanied by release of pro-inflammatory mediators, contributes to accelerate muscle inflammation and muscle weakness. retulator signature
FASLG cuproptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FASLG apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FASLG apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FASLG GO:0000122,GO:0005102,GO:0005123,GO:0005125,GO:0005164,GO:0005515,GO:0005576,GO:0005615,GO:0005634,GO:0005886,GO:0005901,GO:0006915,GO:0006919,GO:0006919,GO:0006925,GO:0007165,GO:0007267,GO:0008284,GO:0008625,GO:0008625,GO:0009897,GO:0016525,GO:0030644,GO:0032496,GO:0043065,GO:0043123,GO:0043123,GO:0043202,GO:0043525,GO:0045742,GO:0046666,GO:0048388,GO:0048471,GO:0060205,GO:0070062,GO:0070231,GO:0070266,GO:0070848,GO:0071346,GO:0097190,GO:0097191,GO:0097527,GO:1903514,GO:1905782,GO:2000353

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FASLG hsa:356 path:hsa01524 Platinum drug resistance - Homo sapiens (human)
FASLG hsa:356 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
FASLG hsa:356 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
FASLG hsa:356 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
FASLG hsa:356 path:hsa04068 FoxO signaling pathway - Homo sapiens (human)
FASLG hsa:356 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
FASLG hsa:356 path:hsa04210 Apoptosis - Homo sapiens (human)
FASLG hsa:356 path:hsa04217 Necroptosis - Homo sapiens (human)
FASLG hsa:356 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
FASLG hsa:356 path:hsa04722 Neurotrophin signaling pathway - Homo sapiens (human)
FASLG hsa:356 path:hsa04932 Non-alcoholic fatty liver disease - Homo sapiens (human)
FASLG hsa:356 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
FASLG hsa:356 path:hsa04940 Type I diabetes mellitus - Homo sapiens (human)
FASLG hsa:356 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
FASLG hsa:356 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
FASLG hsa:356 path:hsa05142 Chagas disease - Homo sapiens (human)
FASLG hsa:356 path:hsa05143 African trypanosomiasis - Homo sapiens (human)
FASLG hsa:356 path:hsa05160 Hepatitis C - Homo sapiens (human)
FASLG hsa:356 path:hsa05161 Hepatitis B - Homo sapiens (human)
FASLG hsa:356 path:hsa05162 Measles - Homo sapiens (human)
FASLG hsa:356 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
FASLG hsa:356 path:hsa05164 Influenza A - Homo sapiens (human)
FASLG hsa:356 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
FASLG hsa:356 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
FASLG hsa:356 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
FASLG hsa:356 path:hsa05200 Pathways in cancer - Homo sapiens (human)
FASLG hsa:356 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
FASLG hsa:356 path:hsa05320 Autoimmune thyroid disease - Homo sapiens (human)
FASLG hsa:356 path:hsa05330 Allograft rejection - Homo sapiens (human)
FASLG hsa:356 path:hsa05332 Graft-versus-host disease - Homo sapiens (human)
FASLG hsa:356 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FASLG FAS 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22075988 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866 interaction type N/A ACSN
DAXX FASLG 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26192618 26587781 26653790 26972597 27984721 28574505 9184224 9488730 9759866 interaction type N/A ACSN
FADD FASLG 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866 interaction type N/A ACSN
FASLG FAF1 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866 interaction type N/A ACSN
RIPK1 FASLG 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866 interaction type N/A ACSN
CFLAR FASLG 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866 interaction type N/A ACSN
TRAF2 FASLG 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26192618 26587781 26653790 26972597 27984721 28574505 9488730 9759866 interaction type N/A ACSN
MLKL FASLG 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16498403 16940415 17462996 18641653 19498109 19524512 19524513 19597341 19632174 19838173 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 24366341 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866 interaction type N/A ACSN
RIPK3 FASLG 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16498403 16940415 17462996 18641653 19498109 19524512 19524513 19597341 19632174 19838173 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 24366341 26024392 26192618 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866 interaction type N/A ACSN
PTPN13 FASLG 12702723 12724420 16498403 23069999 26192618 9184224 interaction type N/A ACSN
FAIM FASLG 12702723 16498403 17942717 23069999 26192618 9184224 interaction type N/A ACSN
SQSTM1 FASLG 12702723 15340068 16252010 16498403 20531300 21981924 23069999 25002027 26192618 26587781 28574505 9184224 interaction type N/A ACSN
EP300 FASLG 15286281 23180781 physical association anti tag coimmunoprecipitation InnateDB
EGR1 FASLG 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB
FYN FASLG 11741599 23180781 physical association pull down InnateDB
FASLG FNBP1 23180781 24291222 physical association anti tag coimmunoprecipitation InnateDB
FASLG PACSIN1 23180781 24291222 physical association anti tag coimmunoprecipitation InnateDB
FASLG PACSIN2 23180781 24291222 physical association anti tag coimmunoprecipitation InnateDB
FASLG PACSIN3 23180781 24291222 physical association anti tag coimmunoprecipitation InnateDB
FASLG SNX9 23180781 24291222 physical association anti tag coimmunoprecipitation InnateDB
FASLG SNX18 23180781 24291222 physical association anti tag coimmunoprecipitation InnateDB
FASLG SNX33 23180781 24291222 physical association anti tag coimmunoprecipitation InnateDB
FASLG TRIP6 23180781 25416956 physical association two hybrid InnateDB
FASLG RGS20 23180781 25416956 physical association two hybrid InnateDB
FASLG KRT40 23180781 25416956 physical association two hybrid InnateDB
FASLG FASLG 14965271 26467481 9228058 bind,up-regulates activity N/A Signor

Source Target Pmid Interactiontype Methods Database
CEBPB FASLG 12496392 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
ETS1 FASLG 11970950 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
GATA2 FASLG 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 FASLG 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SP1 FASLG 11970950 12655294 14563113 15004200 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
FOXP3 FASLG 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 FASLG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FASLG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FASLG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FASLG 14563113 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FASLG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FASLG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FASLG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 FASLG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 FASLG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 FASLG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ATF2 FASLG 19670268 9710625 trascriptional regulation,stimulation inferred by curator TFlink
CIITA FASLG 14563113 trascriptional regulation,stimulation inferred by curator TFlink
CREM FASLG 11754361 trascriptional regulation,stimulation inferred by curator TFlink
EGR2 FASLG 19651900 trascriptional regulation,stimulation inferred by curator TFlink
FOXO3 FASLG 11756562 trascriptional regulation,stimulation inferred by curator TFlink
IRF1 FASLG 14563113 trascriptional regulation,stimulation inferred by curator TFlink
JUN FASLG 14563113 19670268 9710625 trascriptional regulation,stimulation inferred by curator TFlink
MAX FASLG 10734130 trascriptional regulation,stimulation inferred by curator TFlink
MYC FASLG 10734130 12655294 14563113 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 FASLG 10671224 12655294 14563113 15160330 16770006 trascriptional regulation,stimulation inferred by curator TFlink
NR4A1 FASLG 14563113 trascriptional regulation,stimulation inferred by curator TFlink
PDCD11 FASLG 14563113 trascriptional regulation,stimulation inferred by curator TFlink
PPARG FASLG 18293083 trascriptional regulation,stimulation inferred by curator TFlink
RELA FASLG 10671224 12655294 14563113 15160330 16770006 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 FASLG 12655294 14563113 15004200 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D FASLG 20371612 21820586 23177026 rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000009262D FASLG 20371612 21820586 23177026 23504349 24821435 25118289 25394756 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000003ABC4 FASLG 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000085F64 FASLG 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 FASLG 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 FASLG 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F FASLG 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 FASLG 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 FASLG 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D FASLG 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A FASLG 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000000B1C9 FASLG 25416803 26826505 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00001C770D FASLG 25416803 28013316 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000EED18 FASLG 25416803 28097098 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
FASLG FYN 25361965 interaction type N/A PTMCode2
FYN FASLG 25361965 interaction type N/A PTMCode2
FASLG TNFRSF6B 25361965 interaction type N/A PTMCode2
TNFRSF6B FASLG 25361965 interaction type N/A PTMCode2
FASLG FGR 25361965 interaction type N/A PTMCode2
FGR FASLG 25361965 interaction type N/A PTMCode2
FASLG FNBP1 25361965 interaction type N/A PTMCode2
FNBP1 FASLG 25361965 interaction type N/A PTMCode2
MMP7 FASLG 25361965 interaction type N/A PTMCode2
FASLG MMP7 25361965 interaction type N/A PTMCode2
LCK FASLG 25361965 interaction type N/A PTMCode2
FASLG LCK 25361965 interaction type N/A PTMCode2
SNX18 FASLG 25361965 interaction type N/A PTMCode2
FASLG SNX18 25361965 interaction type N/A PTMCode2
CASP10 FASLG 25361965 interaction type N/A PTMCode2
FASLG CASP10 25361965 interaction type N/A PTMCode2
MAPK10 FASLG 25361965 interaction type N/A PTMCode2
FASLG MAPK10 25361965 interaction type N/A PTMCode2
SRC FASLG 25361965 interaction type N/A PTMCode2
FASLG SRC 25361965 interaction type N/A PTMCode2
EZR FASLG 25361965 interaction type N/A PTMCode2
FASLG EZR 25361965 interaction type N/A PTMCode2
PACSIN2 FASLG 25361965 interaction type N/A PTMCode2
FASLG PACSIN2 25361965 interaction type N/A PTMCode2
GRB2 FASLG 25361965 interaction type N/A PTMCode2
FASLG GRB2 25361965 interaction type N/A PTMCode2
FADD FASLG 25361965 interaction type N/A PTMCode2
FASLG FADD 25361965 interaction type N/A PTMCode2
CASP8 FASLG 25361965 interaction type N/A PTMCode2
FASLG CASP8 25361965 interaction type N/A PTMCode2
TNFRSF1A FASLG 25361965 interaction type N/A PTMCode2
FASLG TNFRSF1A 25361965 interaction type N/A PTMCode2
BTK FASLG 25361965 interaction type N/A PTMCode2
FASLG BTK 25361965 interaction type N/A PTMCode2
BID FASLG 25361965 interaction type N/A PTMCode2
FASLG BID 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIN1 FASLG 11741599 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
NCK2 FASLG 19807924 24234451 25348397 physical association phage display,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DAXX FASLG 25348397 N/A in vitro,in vivo ComPPI
YES1 FASLG 19807924 24234451 25348397 physical association phage display,physical interaction ComPPI,IntAct
PACSIN3 FASLG 16318909 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down ComPPI,IntAct
SORBS3 FASLG 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
GRAP FASLG 11741599 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
KRT33B FASLG 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT40 FASLG 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRK FASLG 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
PACSIN1 FASLG 16318909 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down ComPPI,IntAct
MMP7 FASLG 12464266 14525934 24234451 25241761 25348397 27898060 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct,OmniPath
BTK FASLG 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
TEC FASLG 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
MAPK8 FASLG 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
LYN FASLG 19807924 24234451 25348397 physical association phage display,physical interaction ComPPI,IntAct
PIK3R1 FASLG 11741599 14525934 19807924 24234451 25241761 25348397 physical association experimental interaction detection,phage display,physical interaction,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
SRC FASLG 11741599 14525934 19807924 24234451 25348397 physical association experimental interaction detection,phage display,physical interaction,in vivo ComPPI,HPRD,IntAct
GRAP2 FASLG 11741599 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
LCK FASLG 11741599 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
NCK1 FASLG 11741599 14525934 19807924 24234451 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,phage display,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
SKAP2 FASLG 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
GRB2 FASLG 11741599 12023017 12220636 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SUMO1 FASLG 14525934 25348397 8906799 N/A two hybrid,two hybrid ComPPI,HPRD
ITK FASLG 19807924 24234451 25348397 physical association phage display,pull down,physical interaction ComPPI,IntAct
RHOA FASLG 25348397 N/A physical interaction ComPPI
ARHGDIA FASLG 25348397 N/A physical interaction ComPPI
SRGAP1 FASLG 19807924 24234451 25348397 physical association phage display,physical interaction ComPPI,IntAct
KALRN FASLG 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
PIK3CA FASLG 25348397 N/A physical interaction ComPPI
P3H4 FASLG 25348397 N/A physical interaction ComPPI
PRPF40A FASLG 11741599 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TNS2 FASLG 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DLG2 FASLG 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
APBB1 FASLG 11741599 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ARHGAP9 FASLG 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
CASP8 FASLG 12198154 12887920 16498403 24025841 24234451 25348397 association,physical association anti tag coimmunoprecipitation,coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
TNFRSF1A FASLG 25348397 N/A physical interaction ComPPI
TRIP6 FASLG 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NCF1 FASLG 19807924 24234451 25348397 N/A phage display,physical interaction,in vivo ComPPI,IntAct
FADD FASLG 12887920 14525934 16498403 24025841 24234451 25241761 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
TRIP10 FASLG 16318909 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down ComPPI,IntAct
PRMT2 FASLG 25348397 N/A physical interaction ComPPI
SNX9 FASLG 19807924 24234451 25348397 physical association anti tag coimmunoprecipitation,phage display,physical interaction ComPPI,IntAct
SNX18 FASLG 19807924 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPTA1 FASLG 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG EZR 11013215 14525934 15659383 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
FASLG PSTPIP1 14525934 16204241 16318909 19807924 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,phage display,pull down,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
FASLG FAS 12887920 14525934 21803845 24234451 25241761 25348397 9126929 9228058 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cross-linking study,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
FASLG FYN 14525934 19807924 24234451 25241761 25348397 7589480 physical association experimental interaction detection,phage display,physical interaction,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
FASLG KMT2A 12023017 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FASLG PTPN13 14525934 16498403 25348397 9261095 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
FASLG PDCD6 11606059 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
FASLG PACSIN2 12023017 14525934 16318909 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
FASLG FNBP1 12023017 14525934 16318909 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
FASLG TNFRSF10B 25348397 N/A physical interaction ComPPI
FASLG BID 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
FASLG MSN 25348397 N/A physical interaction ComPPI
FASLG CASP10 16498403 24234451 25348397 physical association anti tag coimmunoprecipitation,coimmunoprecipitation,physical interaction ComPPI,IntAct
FASLG FN1 11276204 14525934 24234451 25241761 25348397 27898060 physical association experimental interaction detection,physical interaction,proximity ligation assay ComPPI,HPRD,IntAct,OmniPath
FASLG FGR 25348397 N/A physical interaction ComPPI
FASLG ITSN2 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG SNX33 19807924 24234451 25348397 physical association anti tag coimmunoprecipitation,phage display,physical interaction ComPPI,IntAct
FASLG HCK 19807924 24234451 25348397 physical association phage display,physical interaction ComPPI,IntAct
FASLG SH3PXD2B 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG EPS8L3 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG MYO15A 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG FYB1 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG SAMSN1 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG SH3RF2 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG NCKIPSD 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG SH3PXD2A 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG BAIAP2L1 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG SH3GL3 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG TJP3 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG CACNB3 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG MPP4 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG DNMBP 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG DOCK4 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG MACC1 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG SRGAP3 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG RAB4B 25348397 N/A physical interaction ComPPI
FASLG MIA 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG SRGAP2 16318909 19807924 24234451 25348397 physical association phage display,pull down,physical interaction ComPPI,IntAct
FASLG NCF1B 25348397 N/A physical interaction ComPPI
FASLG CACNB4 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG RIMBP3C 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
FASLG RGS20 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FASLG NOTCH2NLA 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FASLG CLPX 25348397 N/A physical interaction ComPPI
FASLG EIF2AK1 25348397 N/A physical interaction ComPPI
FASLG P3H3 25348397 N/A physical interaction ComPPI
FASLG MOSPD2 25348397 N/A physical interaction ComPPI
FASLG A1BG 25348397 N/A coimmunoprecipitation,physical interaction,surface plasmon resonance array ComPPI
FASLG ARHGAP4 16318909 24234451 25348397 physical association pull down ComPPI,IntAct
FASLG SEC23A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FASLG CYSRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FASLG ECM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FASLG KRTAP12-3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FASLG IHO1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CFLAR FASLG 25348397 N/A physical interaction ComPPI
OSTF1 FASLG 19807924 24234451 25348397 physical association phage display,physical interaction ComPPI,IntAct
TNFRSF6B FASLG 21300286 24234451 25348397 N/A surface plasmon resonance,physical interaction,in vivo,surface plasmon resonance array ComPPI,IntAct
KRTAP11-1 FASLG 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DMD FASLG 11741599 14525934 N/A experimental interaction detection HPRD
FASLG FASLG 21713032 24234451 N/A molecular sieving IntAct
FYN FASLG 11741599 17164290 19807924 25241761 27898060 7589480 N/A N/A OmniPath
FASLG FYN 11741599 17164290 19807924 25241761 27898060 7589480 N/A N/A OmniPath
FASLG PACSIN3 16318909 24291222 27898060 N/A N/A OmniPath
EGR1 FASLG 11909874 27898060 stimulant N/A OmniPath
FOXO3 FASLG 10102273 14976264 16865280 27898060 inhibition,stimulant N/A OmniPath
STAT1 FASLG 12108949 27898060 stimulant N/A OmniPath
TP53 FASLG 10969818 27898060 9841917 stimulant N/A OmniPath
FASLG FAS 12753742 12887920 1375228 14965271 15659383 15725726 1713127 21803845 25241761 27898060 7505205 8521815 9039262 9126929 9228058 stimulant N/A OmniPath
FNBP1 FASLG 12023017 16318909 24291222 27898060 N/A N/A OmniPath
FASLG PACSIN1 16318909 24291222 27898060 N/A N/A OmniPath
FASLG SNX33 19807924 24291222 26186194 27898060 N/A N/A OmniPath
FASLG SNX9 19807924 24291222 26186194 27898060 N/A N/A OmniPath
FASLG PACSIN2 12023017 16318909 24291222 27898060 N/A N/A OmniPath
PACSIN2 FASLG 12023017 16318909 24291222 27898060 N/A N/A OmniPath
FASLG SNX18 19807924 24291222 27898060 N/A N/A OmniPath
TNFRSF6B FASLG 10318773 11994433 27898060 9872321 inhibition N/A OmniPath
FASLG TNFRSF6B 10318773 11994433 14697332 27898060 9872321 stimulant N/A OmniPath

Visualization










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