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GENE：IL3RA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IL3RA
FullNmae interleukin 3 receptor subunit alpha
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6012
EnsembleID ENSG00000185291
Uniprot P26951

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IL3RA immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IL3RA apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IL3RA GO:0004896,GO:0004912,GO:0005515,GO:0005886,GO:0005886,GO:0009897,GO:0019221,GO:0019955,GO:0036016,GO:0038156,GO:0043235

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IL3RA hsa:3563 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
IL3RA hsa:3563 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
IL3RA hsa:3563 path:hsa04210 Apoptosis - Homo sapiens (human)
IL3RA hsa:3563 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)
IL3RA hsa:3563 path:hsa04640 Hematopoietic cell lineage - Homo sapiens (human)
IL3RA hsa:3563 path:hsa05200 Pathways in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL3RA IL3 23180781 7957082 physical association saturation binding InnateDB
IL3RA BCL6 19965633 23180781 physical association anti tag coimmunoprecipitation InnateDB
PLCG1 IL3RA 17474147 23180781 physical association peptide array InnateDB
IL3 IL3RA 1465408 23331499 stimulation N/A SignaLink,SignaLink
IL3RA JAK2 15795318 23331499 stimulation N/A SignaLink,SignaLink
IL3RA STAT5A 10582086 23331499 stimulation N/A SignaLink,SignaLink

Source Target Pmid Interactiontype Methods Database
SP1 IL3RA N/A trascriptional regulation,stimulation inferred by curator TFlink
SPI1 IL3RA N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CSF2 IL3RA 25361965 interaction type N/A PTMCode2
IL3RA CSF2 25361965 interaction type N/A PTMCode2
IL3RA JAK1 25361965 interaction type N/A PTMCode2
JAK1 IL3RA 25361965 interaction type N/A PTMCode2
IL3RA JAK2 25361965 interaction type N/A PTMCode2
JAK2 IL3RA 25361965 interaction type N/A PTMCode2
IL3RA CSF2RB 25361965 interaction type N/A PTMCode2
CSF2RB IL3RA 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SMAGP IL3RA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP1CC IL3RA 25348397 N/A physical interaction ComPPI
VAMP5 IL3RA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSF2 IL3RA 14525934 25348397 7957082 N/A experimental interaction detection,in vitro ComPPI,HPRD
JAGN1 IL3RA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SERP1 IL3RA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NCK1 IL3RA 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
GRB2 IL3RA 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
JAK1 IL3RA 14525934 15988755 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CISH IL3RA 14525934 25348397 7796808 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
NR0B2 IL3RA 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SAE1 IL3RA 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
C2CD2L IL3RA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
JAK2 IL3RA 14525934 15988755 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FYN IL3RA 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
IL3RA CSF2RB 14525934 25348397 8649415 N/A experimental interaction detection,in vitro ComPPI,HPRD
IL3RA IL3 14525934 25348397 8649415 9278420 N/A coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
IL3RA LNX1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL3RA FOXP1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL3RA SGK2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL3RA CDK1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL3RA CDC25A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL3RA GNA12 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL3RA PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
IL3RA SYS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IL3RA GIMAP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IL3RA TMEM65 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IL3RA TMEM254 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EMP3 IL3RA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PAQR5 IL3RA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLCG1 IL3RA 17474147 27898060 N/A N/A OmniPath
IL3RA STAT5A 10582086 27898060 stimulant N/A OmniPath
ZBTB16 IL3RA 19723763 27898060 stimulant N/A OmniPath
IL3 IL3RA 11700046 1465408 27898060 7957082 8649415 9278420 stimulant N/A OmniPath
IL3RA JAK2 15795318 15988755 17312100 27898060 stimulant N/A OmniPath
CSF2RB IL3RA 11700046 27898060 8649415 N/A N/A OmniPath

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