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GENE：KDR

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KDR
FullNmae kinase insert domain receptor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6307
EnsembleID ENSG00000128052
Uniprot P35968

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KDR mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KDR autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KDR autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
KDR apoptosis 38918393 Inhibition of KDR specifically induces apoptosis of Tax expressing HTLV-1-transformed cell lines and CD4 + T cells from HAM/TSP patients. retulator signature

Go Annotation:

GeneSymbol Go id
KDR GO:0001525,GO:0001525,GO:0001541,GO:0001569,GO:0001570,GO:0001934,GO:0001938,GO:0001945,GO:0002042,GO:0002053,GO:0002070,GO:0003157,GO:0003158,GO:0004713,GO:0004713,GO:0004714,GO:0005021,GO:0005021,GO:0005178,GO:0005515,GO:0005524,GO:0005576,GO:0005634,GO:0005768,GO:0005769,GO:0005783,GO:0005794,GO:0005886,GO:0005886,GO:0005886,GO:0007169,GO:0007275,GO:0008284,GO:0008284,GO:0008360,GO:0009897,GO:0010463,GO:0010595,GO:0010629,GO:0015026,GO:0016239,GO:0016477,GO:0018108,GO:0019838,GO:0030054,GO:0030335,GO:0030335,GO:0030335,GO:0030513,GO:0033674,GO:0035162,GO:0035584,GO:0035924,GO:0035924,GO:0036324,GO:0038033,GO:0038083,GO:0038084,GO:0038085,GO:0042802,GO:0043066,GO:0043129,GO:0043235,GO:0043408,GO:0043410,GO:0043491,GO:0043524,GO:0043536,GO:0045121,GO:0045165,GO:0045296,GO:0045446,GO:0045766,GO:0045766,GO:0046777,GO:0048010,GO:0048010,GO:0048010,GO:0048286,GO:0048597,GO:0050673,GO:0050927,GO:0051770,GO:0051770,GO:0051879,GO:0051894,GO:0051897,GO:0051901,GO:0055074,GO:0060837,GO:0061042,GO:0070161,GO:0070371,GO:0070374,GO:0071526,GO:0072089,GO:0090050,GO:0090141,GO:0097443,GO:1901532,GO:1903010,GO:1904881,GO:2000352,GO:2000648,GO:2001214

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KDR hsa:3791 path:hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human)
KDR hsa:3791 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
KDR hsa:3791 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
KDR hsa:3791 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
KDR hsa:3791 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
KDR hsa:3791 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
KDR hsa:3791 path:hsa04370 VEGF signaling pathway - Homo sapiens (human)
KDR hsa:3791 path:hsa04510 Focal adhesion - Homo sapiens (human)
KDR hsa:3791 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
KDR hsa:3791 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
VEGFA KDR 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 association N/A ACSN
VEGFB KDR 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
GRB2 KDR 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
KDR NCK1 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
SHC1 KDR 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
CRK KDR 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26192618 26201938 8837607 9157999 9570538 9753319 interaction type N/A ACSN
CRKL KDR 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26192618 26201938 8837607 9157999 9570538 9753319 interaction type N/A ACSN
KDR FLT4 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26192618 26201938 8837607 9157999 9570538 9753319 interaction type N/A ACSN
THBS1 KDR 10657674 11982756 14568985 14996710 22943793 26192618 8349738 interaction type N/A ACSN
KDR SYK 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615 interaction type N/A ACSN
KDR PIK3R1 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
KDR PLCG1 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
KDR FYN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
KDR STAT3 15703780 23180781 physical association anti tag coimmunoprecipitation InnateDB
KDR STAT1 15703780 23180781 physical association anti tag coimmunoprecipitation InnateDB
KDR IQGAP1 15217908 23180781 physical association anti tag coimmunoprecipitation InnateDB
SHC2 KDR 10749680 1220983 23331499 stimulation N/A SignaLink
KDR ANXA5 10329451 23331499 stimulation N/A SignaLink
KDR SHC2 10749680 23331499 9790910 stimulation N/A SignaLink
KDR SHC1 11950700 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ANXA5 KDR 20005715 interaction type N/A PSP
CAV1 KDR 20005715 interaction type N/A PSP
CRK KDR 15051508 18988627 20005715 interaction type N/A PSP,SignaLink
FRS2 KDR 12154000 18988627 20005715 interaction type N/A PSP,SignaLink
GRB10 KDR 20005715 interaction type N/A PSP
GRB2 KDR 20005715 interaction type N/A PSP
NCK1 KDR 20005715 interaction type N/A PSP,SignaLink
SH2D2A KDR 10692392 15962004 18988627 20005715 interaction type N/A PSP,SignaLink
SHB KDR 15026417 18988627 20005715 interaction type N/A PSP,SignaLink
SHC1 KDR 10319320 10749680 18988627 20005715 21071413 interaction type N/A PSP,SignaLink
SHC2 KDR 20005715 interaction type N/A PSP,SignaLink
CAV1 KDR 12529448 18988627 20005715 N/A N/A SignaLink
GRB2 KDR 10319320 20005715 21071413 N/A N/A SignaLink
ANXA5 KDR 10329451 10329451 20005715 20005715 21071413 N/A N/A SignaLink
GRB10 KDR 11494124 18988627 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ESR1 KDR 16574784 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
SP1 KDR 16574784 16678129 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
SP3 KDR 16574784 16678129 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
SP4 KDR 16574784 16678129 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
CTCF KDR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 KDR 18971253 20516113 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 KDR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 KDR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS KDR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 KDR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF KDR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HEY1 KDR 16782059 17028039 18694572 trascriptional regulation,stimulation inferred by curator TFlink
NANOG KDR 21119109 trascriptional regulation,stimulation inferred by curator TFlink
PTTG1 KDR 16926250 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 KDR 16678129 trascriptional regulation,stimulation inferred by curator TFlink
EPAS1 KDR N/A trascriptional regulation,stimulation inferred by curator TFlink
ETS1 KDR N/A trascriptional regulation,stimulation inferred by curator TFlink
HIF1A KDR N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000012A1DD KDR 21544626 rna interference,inhibition western blot,miRNA interference luciferase reporter assay miRSponge
URS000013D17D KDR 22197821 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000012A1DD KDR 21544626 22499991 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 KDR 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00002075FA KDR 23258273 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000171525 KDR 24205206 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS000041CB9C KDR 23688497 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000075B13F KDR 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C KDR 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001C3AC1 KDR 25416803 26500043 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS000040EE1D KDR 25416803 27572273 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
SRC KDR 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
KDR KDR 22135298 phosphorylation N/A PhosphoSite
KDR PFN1 22135298 phosphorylation N/A PhosphoSite
CDK5 KDR 22135298 phosphorylation N/A PhosphoSite
KDR CBL 25361965 interaction type N/A PTMCode2
CBL KDR 25361965 interaction type N/A PTMCode2
KDR SHC2 25361965 interaction type N/A PTMCode2
SHC2 KDR 25361965 interaction type N/A PTMCode2
KDR TIMP3 25361965 interaction type N/A PTMCode2
TIMP3 KDR 25361965 interaction type N/A PTMCode2
KDR IQGAP1 25361965 interaction type N/A PTMCode2
IQGAP1 KDR 25361965 interaction type N/A PTMCode2
KDR VEGFC 25361965 interaction type N/A PTMCode2
VEGFC KDR 25361965 interaction type N/A PTMCode2
KDR FLT1 25361965 interaction type N/A PTMCode2
FLT1 KDR 25361965 interaction type N/A PTMCode2
KDR NCK1 25361965 interaction type N/A PTMCode2
NCK1 KDR 25361965 interaction type N/A PTMCode2
KDR FRS2 25361965 interaction type N/A PTMCode2
FRS2 KDR 25361965 interaction type N/A PTMCode2
KDR CRK 25361965 interaction type N/A PTMCode2
CRK KDR 25361965 interaction type N/A PTMCode2
KDR YES1 25361965 interaction type N/A PTMCode2
YES1 KDR 25361965 interaction type N/A PTMCode2
KDR GRB2 25361965 interaction type N/A PTMCode2
GRB2 KDR 25361965 interaction type N/A PTMCode2
KDR CAV1 25361965 interaction type N/A PTMCode2
CAV1 KDR 25361965 interaction type N/A PTMCode2
KDR CDH5 25361965 interaction type N/A PTMCode2
CDH5 KDR 25361965 interaction type N/A PTMCode2
KDR CTNNB1 25361965 interaction type N/A PTMCode2
CTNNB1 KDR 25361965 interaction type N/A PTMCode2
KDR SRC 25361965 interaction type N/A PTMCode2
KDR PLCG2 25361965 interaction type N/A PTMCode2
PLCG2 KDR 25361965 interaction type N/A PTMCode2
KDR FYN 25361965 interaction type N/A PTMCode2
FYN KDR 25361965 interaction type N/A PTMCode2
KDR SHB 25361965 interaction type N/A PTMCode2
SHB KDR 25361965 interaction type N/A PTMCode2
KDR GRB10 25361965 interaction type N/A PTMCode2
GRB10 KDR 25361965 interaction type N/A PTMCode2
KDR PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 KDR 25361965 interaction type N/A PTMCode2
KDR SHC1 25361965 interaction type N/A PTMCode2
SHC1 KDR 25361965 interaction type N/A PTMCode2
ITGB3 KDR 25361965 interaction type N/A PTMCode2
KDR ITGB3 25361965 interaction type N/A PTMCode2
FLT4 KDR 25361965 interaction type N/A PTMCode2
KDR FLT4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
AIMP2 KDR 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
YES1 KDR 14525934 25348397 7929439 N/A experimental interaction detection,in vitro ComPPI,HPRD
NPM1 KDR 25348397 N/A physical interaction ComPPI
STAT1 KDR 10961983 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ZSCAN21 KDR 25348397 N/A physical interaction ComPPI
YWHAG KDR 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTPN6 KDR 14525934 16453023 18377662 24234451 25348397 9405464 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CRK KDR 14525934 15051508 23397142 24234451 25348397 physical association experimental interaction detection,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
CSNK1D KDR 25348397 N/A physical interaction ComPPI
TXNIP KDR 25348397 N/A physical interaction ComPPI
CBL KDR 12649282 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MAPK1 KDR 25348397 N/A physical interaction ComPPI
SHB KDR 14525934 15026417 24234451 25348397 association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN11 KDR 14525934 25348397 9405464 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SRC KDR 10455194 12509223 14525934 16966330 18377662 18662404 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,far western blotting,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
GRB10 KDR 11494124 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
FLT1 KDR 10865839 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
KDR GRB2 10319320 14525934 16966330 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
KDR VEGFA 14525934 16763549 17318185 20660291 23374253 23583373 24234451 25348397 8621427 physical association affinity chromatography technology,biophysical,coimmunoprecipitation,cross-linking study,experimental interaction detection,filter binding,isothermal titration calorimetry,physical interaction,biochemical,enzyme linked immunosorbent assay,in vivo,proximity ligation assay,solid phase assay,surface plasmon resonance array ComPPI,HPRD,IntAct
KDR VEGFD 14525934 25348397 9435229 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
KDR PLCG2 25348397 N/A in vivo ComPPI
KDR SHC1 10749680 11950700 12214271 14525934 24234451 25348397 association,physical association two hybrid,coimmunoprecipitation,pull down,physical interaction,two hybrid ComPPI,HPRD,IntAct
KDR CDH5 10428027 11950700 14525934 18662404 24234451 25348397 association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
KDR VEGFC 11332691 14525934 20145116 24234451 25348397 physical association experimental interaction detection,isothermal titration calorimetry,light scattering,molecular sieving,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
KDR ATR 10749680 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
KDR FLT4 14525934 15474514 16530705 20224550 21130043 24234451 25348397 physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
KDR P2RY2 25348397 N/A in vitro,in vivo ComPPI
KDR COL18A1 12029087 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
KDR HSP90AA1 14525934 15247219 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
KDR RASA1 10319320 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
KDR ITGB3 10022831 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
KDR NCK1 14525934 16966330 24234451 25348397 9405464 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
KDR GNA11 12670961 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
KDR GNAQ 12670961 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
KDR CAV1 12529448 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
KDR FRS2 12154000 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
KDR CSF2RB 14525934 16007196 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
KDR FYN 14525934 16966330 24234451 25348397 7929439 physical association anti tag coimmunoprecipitation,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
KDR TIMP3 12652295 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
KDR CTNNB1 12920240 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
KDR SYNGAP1 14525934 25348397 9405464 N/A experimental interaction detection,in vitro ComPPI,HPRD
KDR SHC2 10749680 14525934 25348397 9790910 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
KDR ANXA5 10329451 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
KDR ITGA2 21596751 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
KDR HSPG2 21596751 23374253 24234451 25348397 N/A anti bait coimmunoprecipitation,filter binding,enzyme linked immunosorbent assay ComPPI,IntAct
KDR PLXNA1 25348397 N/A physical interaction ComPPI
KDR ACP1 10608891 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
KDR PLCG1 12598525 14525934 24234451 25348397 association experimental interaction detection,pull down,physical interaction ComPPI,HPRD,IntAct
KDR FBXW11 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KDR BTRC 21402774 22711876 25348397 27898060 N/A physical interaction ComPPI,OmniPath
KDR CUL1 25348397 N/A physical interaction ComPPI
KDR EPN1 25348397 N/A physical interaction ComPPI
KDR MYO1C 25348397 N/A physical interaction ComPPI
KDR FBXO25 25348397 N/A physical interaction ComPPI
KDR RAB5A 25348397 N/A physical interaction ComPPI
KDR NRP1 11333271 14525934 16763549 17222790 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
KDR NCOA4 25348397 N/A physical interaction ComPPI
KDR PALLD 25348397 N/A physical interaction ComPPI
KDR AAR2 25348397 N/A physical interaction ComPPI
KDR NAXD 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KDR TUT7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KDR SH2D2A 10692392 14525934 15962004 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
KDR APP 25348397 N/A physical interaction ComPPI
KDR PTPN12 25348397 N/A physical interaction ComPPI
KDR PTPRR 25348397 N/A physical interaction ComPPI
KDR PPM1A 25348397 N/A physical interaction ComPPI
KDR PPM1B 25348397 N/A physical interaction ComPPI
KDR ILKAP 25348397 N/A physical interaction ComPPI
KDR DUSP19 25348397 N/A physical interaction ComPPI
KDR STYX 25348397 N/A physical interaction ComPPI
KDR DNM2 14525934 16049137 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
KDR PDGFRB 18997771 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
KDR A1BG 25348397 N/A coimmunoprecipitation,physical interaction ComPPI
KDR PTPRJ 18936167 24234451 25348397 dephosphorylation reaction,physical association coimmunoprecipitation,pull down,biochemical,phosphatase assay ComPPI,IntAct
KDR MET 22789536 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
KDR PDCD6 21893193 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid ComPPI,IntAct,OmniPath
KDR GREM1 20660291 24234451 25348397 physical association cross-linking study,surface plasmon resonance,enzyme linked immunosorbent assay,surface plasmon resonance array ComPPI,IntAct
KDR LGALS1 24234451 24529377 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,fluorescent resonance energy transfer ComPPI,IntAct
KDR EEA1 23799140 24234451 25348397 physical association proximity ligation assay ComPPI,IntAct
KDR RALGDS 23175184 24234451 25348397 association pull down ComPPI,IntAct
IQGAP1 KDR 14525934 15217908 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PKM KDR 25348397 N/A protein kinase assay ComPPI
BMX KDR 14525934 14532277 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
GATC KDR 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KDR KDR 10368301 10579917 10749680 14525934 17293873 20080685 20660291 24234451 physical association transmission electron microscopy,cosedimentation in solution,experimental interaction detection,surface plasmon resonance,x-ray crystallography HPRD,IntAct
LRP8 KDR 24234451 30139844 physical association anti bait coimmunoprecipitation,proximity ligation assay IntAct
HSPD1 KDR 24234451 30021884 physical association cross-linking study IntAct
ATP5F1A KDR 24234451 30021884 physical association cross-linking study IntAct
SRC KDR 10455194 10749680 11387210 12214271 14532277 16286478 16966330 17303569 17372230 18194650 18377662 18662404 19050761 20176926 25119572 27898060 stimulant N/A OmniPath
KDR PLCG1 10672011 12598525 16835467 27898060 stimulant N/A OmniPath
TRPM7 KDR 10579917 11435426 11741094 27898060 N/A N/A OmniPath
PTPN2 KDR 18840653 19737086 27898060 inhibition N/A OmniPath
VEGFA KDR 11333271 12716911 16423422 16763549 17318185 17658244 18325345 20145116 20660291 23374253 23583373 27898060 8356051 8621427 8631822 9556609 inhibition,stimulant N/A OmniPath
PTPN6 KDR 16453023 18377662 18840653 27898060 9405464 inhibition N/A OmniPath
STAT1 KDR 10961983 15703780 27898060 N/A N/A OmniPath
KDR SHC1 10319320 10749680 11950700 12214271 27898060 stimulant N/A OmniPath
PTPN11 KDR 19706677 27898060 9405464 inhibition N/A OmniPath
STAT3 KDR 15703780 27898060 N/A N/A OmniPath
KDR ANXA5 10329451 27898060 stimulant N/A OmniPath
PTPRB KDR 19136612 27898060 inhibition N/A OmniPath
KDR SHC2 1074968 10749680 1220983 27898060 9790910 stimulant N/A OmniPath
SHC2 KDR 1074968 10749680 1220983 27898060 9790910 stimulant N/A OmniPath
ACP1 KDR 10608891 27898060 N/A N/A OmniPath
VEGFD KDR 11279005 11574540 27898060 9435229 stimulant N/A OmniPath
VEGFC KDR 11332691 20145116 27898060 9435229 stimulant N/A OmniPath
PTPRJ KDR 18936167 27898060 inhibition N/A OmniPath

Visualization










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