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GENE：KRAS

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KRAS
FullNmae KRAS proto-oncogene, GTPase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6407
EnsembleID ENSG00000133703
Uniprot P01116

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KRAS mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KRAS immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KRAS ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KRAS apoptosis 35883626 KRAS, one of the RAS protein family members, plays an important role in autophagy and apoptosis, through the regulation of several downstream effectors. retulator signature

Go Annotation:

GeneSymbol Go id
KRAS GO:0000139,GO:0000165,GO:0001934,GO:0003924,GO:0003924,GO:0003924,GO:0003925,GO:0005515,GO:0005525,GO:0005737,GO:0005741,GO:0005789,GO:0005829,GO:0005886,GO:0005886,GO:0005925,GO:0007265,GO:0008542,GO:0009898,GO:0010628,GO:0014009,GO:0016020,GO:0016601,GO:0019003,GO:0021897,GO:0030036,GO:0030857,GO:0032228,GO:0035022,GO:0035914,GO:0038002,GO:0043495,GO:0043524,GO:0044877,GO:0048169,GO:0048873,GO:0051146,GO:0051402,GO:0060252,GO:0060441,GO:0060509

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KRAS hsa:3845 path:hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human)
KRAS hsa:3845 path:hsa01522 Endocrine resistance - Homo sapiens (human)
KRAS hsa:3845 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04012 ErbB signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04068 FoxO signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04071 Sphingolipid signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04137 Mitophagy - animal - Homo sapiens (human)
KRAS hsa:3845 path:hsa04140 Autophagy - animal - Homo sapiens (human)
KRAS hsa:3845 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04210 Apoptosis - Homo sapiens (human)
KRAS hsa:3845 path:hsa04211 Longevity regulating pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human)
KRAS hsa:3845 path:hsa04218 Cellular senescence - Homo sapiens (human)
KRAS hsa:3845 path:hsa04360 Axon guidance - Homo sapiens (human)
KRAS hsa:3845 path:hsa04370 VEGF signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04371 Apelin signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04540 Gap junction - Homo sapiens (human)
KRAS hsa:3845 path:hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)
KRAS hsa:3845 path:hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
KRAS hsa:3845 path:hsa04660 T cell receptor signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04662 B cell receptor signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04714 Thermogenesis - Homo sapiens (human)
KRAS hsa:3845 path:hsa04720 Long-term potentiation - Homo sapiens (human)
KRAS hsa:3845 path:hsa04722 Neurotrophin signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04725 Cholinergic synapse - Homo sapiens (human)
KRAS hsa:3845 path:hsa04726 Serotonergic synapse - Homo sapiens (human)
KRAS hsa:3845 path:hsa04730 Long-term depression - Homo sapiens (human)
KRAS hsa:3845 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
KRAS hsa:3845 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04912 GnRH signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human)
KRAS hsa:3845 path:hsa04915 Estrogen signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04916 Melanogenesis - Homo sapiens (human)
KRAS hsa:3845 path:hsa04917 Prolactin signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04921 Oxytocin signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04926 Relaxin signaling pathway - Homo sapiens (human)
KRAS hsa:3845 path:hsa04929 GnRH secretion - Homo sapiens (human)
KRAS hsa:3845 path:hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)
KRAS hsa:3845 path:hsa04935 Growth hormone synthesis, secretion and action - Homo sapiens (human)
KRAS hsa:3845 path:hsa04960 Aldosterone-regulated sodium reabsorption - Homo sapiens (human)
KRAS hsa:3845 path:hsa05010 Alzheimer disease - Homo sapiens (human)
KRAS hsa:3845 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
KRAS hsa:3845 path:hsa05034 Alcoholism - Homo sapiens (human)
KRAS hsa:3845 path:hsa05160 Hepatitis C - Homo sapiens (human)
KRAS hsa:3845 path:hsa05161 Hepatitis B - Homo sapiens (human)
KRAS hsa:3845 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
KRAS hsa:3845 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
KRAS hsa:3845 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
KRAS hsa:3845 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
KRAS hsa:3845 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
KRAS hsa:3845 path:hsa05200 Pathways in cancer - Homo sapiens (human)
KRAS hsa:3845 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)
KRAS hsa:3845 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
KRAS hsa:3845 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)
KRAS hsa:3845 path:hsa05207 Chemical carcinogenesis - receptor activation - Homo sapiens (human)
KRAS hsa:3845 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
KRAS hsa:3845 path:hsa05210 Colorectal cancer - Homo sapiens (human)
KRAS hsa:3845 path:hsa05211 Renal cell carcinoma - Homo sapiens (human)
KRAS hsa:3845 path:hsa05212 Pancreatic cancer - Homo sapiens (human)
KRAS hsa:3845 path:hsa05213 Endometrial cancer - Homo sapiens (human)
KRAS hsa:3845 path:hsa05214 Glioma - Homo sapiens (human)
KRAS hsa:3845 path:hsa05215 Prostate cancer - Homo sapiens (human)
KRAS hsa:3845 path:hsa05216 Thyroid cancer - Homo sapiens (human)
KRAS hsa:3845 path:hsa05218 Melanoma - Homo sapiens (human)
KRAS hsa:3845 path:hsa05219 Bladder cancer - Homo sapiens (human)
KRAS hsa:3845 path:hsa05220 Chronic myeloid leukemia - Homo sapiens (human)
KRAS hsa:3845 path:hsa05221 Acute myeloid leukemia - Homo sapiens (human)
KRAS hsa:3845 path:hsa05223 Non-small cell lung cancer - Homo sapiens (human)
KRAS hsa:3845 path:hsa05224 Breast cancer - Homo sapiens (human)
KRAS hsa:3845 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
KRAS hsa:3845 path:hsa05226 Gastric cancer - Homo sapiens (human)
KRAS hsa:3845 path:hsa05230 Central carbon metabolism in cancer - Homo sapiens (human)
KRAS hsa:3845 path:hsa05231 Choline metabolism in cancer - Homo sapiens (human)
KRAS hsa:3845 path:hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human)
KRAS hsa:3845 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
KRAS RAP1GDS1 11948427 23180781 physical association two hybrid InnateDB
KRAS RASSF2 12732644 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
KRAS SHOC2 10783161 23180781 physical association two hybrid InnateDB
RAF1 KRAS 10783161 23180781 physical association two hybrid InnateDB
KRAS RALGDS 10783161 23180781 physical association two hybrid InnateDB
LGALS3 KRAS 15205467 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP KRAS 21832049 23180781 physical association protein array InnateDB
ARAF KRAS 23180781 25416956 physical association two hybrid InnateDB
KRAS MAPK1 10209122 10409742 10725339 10891492 12473660 12832465 14636584 14970219 15035987 15543157 16135787 16879721 17496912 17563371 19091303 19219045 19242111 19279408 21779496 22177953 22510884 22569528 23352452 24957944 25907612 29145629 3287375 7565670 7565795 7731720 7929275 7935411 8051079 8157000 9020159 9858547 physical association inferred by curator Reactome
KRAS MAPK3 10209122 10409742 10725339 10891492 12473660 12832465 14636584 14970219 15035987 15543157 16135787 16879721 17496912 17563371 19091303 19219045 19242111 19279408 21779496 22177953 22510884 22569528 23352452 24957944 25907612 29145629 3287375 7565670 7565795 7731720 7929275 7935411 8051079 8157000 9020159 9858547 physical association inferred by curator Reactome
KRAS SOS1 10722704 11157491 11429702 12147692 1371879 1377053 15118125 15284455 1569084 16024644 16129412 16483568 1721591 18381441 18757403 19103595 19946327 20179196 21160078 21666749 21711248 24243840 24588013 25467007 29145629 7731718 7970720 8388543 8493579 8530489 8530511 8622888 9038378 9070211 9690470 9739761 9857065 enzymatic reaction inferred by curator Reactome
KRAS VAV1 1377053 1569084 29145629 enzymatic reaction inferred by curator Reactome
KRAS IRS2 24243840 29145629 enzymatic reaction inferred by curator Reactome
KRAS IRS1 24243840 29145629 enzymatic reaction inferred by curator Reactome
RASGRP1 KRAS 10777492 10835426 10934204 11221888 17283063 29145629 enzymatic reaction inferred by curator Reactome
KRAS RASGRP3 10777492 10835426 10934204 11221888 17283063 29145629 enzymatic reaction inferred by curator Reactome
SHOC2 KRAS 10783161 18988627 21071413 23331499 9674433 stimulation N/A SignaLink,SignaLink
KRAS RAF1 10882715 16293107 21071413 23331499 stimulation N/A SignaLink,SignaLink
KRAS BRAF 17635919 23331499 stimulation N/A SignaLink,SignaLink
KRAS MAP3K1 23331499 8649450 stimulation N/A SignaLink
PRKCA KRAS 23331499 9922370 stimulation N/A SignaLink
KRAS MAP4K5 23331499 9949177 stimulation N/A SignaLink
SOS1 KRAS 16293107 23331499 stimulation N/A SignaLink
KRAS MINK1 16337592 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 KRAS 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 KRAS 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 KRAS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA KRAS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KRAS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 KRAS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 KRAS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 KRAS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 KRAS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 KRAS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS KRAS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A KRAS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 KRAS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 KRAS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC KRAS 21252116 trascriptional regulation,stimulation inferred by curator TFlink
ETS2 KRAS N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 KRAS \N rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000A07C1 KRAS \N rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS000029979D KRAS 18308936 \N rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00001D69F6 KRAS 22384141 rna interference,inhibition array technology,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS0000008A99 KRAS 19137007 19157460 23276710 \N rna interference,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000338542 KRAS 20584899 rna interference,inhibition experimental interaction detection miRSponge
URS000018C928 KRAS 20080834 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000035CC3E KRAS 19372139 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000060B2B KRAS 20675343 rna interference,inhibition experimental interaction detection,miRNA interference luciferase reporter assay miRSponge
URS000016FF9C KRAS 20610624 rna interference,inhibition experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry miRSponge
URS0000324096 KRAS 18927107 mrna cleavage,inhibition N/A miR2Disease
URS00000A07C1 KRAS 18927107 mrna cleavage,inhibition N/A miR2Disease
URS000029979D KRAS 18308936 18927107 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay miR2Disease,TarBase
URS0000008A99 KRAS 18927107 19137007 19157460 23128394 23276710 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS000035CC3E KRAS 19372139 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000018C928 KRAS 20080834 23667495 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000338542 KRAS 18668040 19193853 20584899 22473208 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,clip TarBase
URS000016FF9C KRAS 20371350 20610624 23752186 25256312 25416803 mrna cleavage,inhibition experimental interaction detection,nucleotide sequence identification,western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000046CDA6 KRAS 21878506 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001D69F6 KRAS 22384141 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS0000060B2B KRAS 20675343 25416803 mrna cleavage,inhibition experimental interaction detection,miRNA interference luciferase reporter assay TarBase
URS00000AA464 KRAS 20304954 24374827 24398324 25416803 25905463 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000272A92 KRAS 23775631 24440911 25416803 27012554 27830015 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS0000184017 KRAS 23667495 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS0000101787 KRAS 23667495 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS000000C73C KRAS 23667495 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS0000007FBA KRAS 23667495 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS000024DFCE KRAS 23880861 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000015B295 KRAS 23426183 25416803 mrna cleavage,inhibition array technology,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000031B6ED KRAS 24374827 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000171525 KRAS 24368337 24398324 25416803 26392416 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00001B341F KRAS 24154848 25416803 25436011 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000034B6F5 KRAS 24855559 25246801 25416803 25500542 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS0000308E4D KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000AB32B KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001A6D0C KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000007A060 KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000A939F KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000055BBE5 KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000012A1DD KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000367985 KRAS 24398324 25416803 27669434 mrna cleavage,inhibition western blot,clip,miRNA interference luciferase reporter assay TarBase
URS0000345DEB KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000070B1D KRAS 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000ECE9C KRAS 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 KRAS 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000453664 KRAS 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002B7450 KRAS 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 KRAS 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF KRAS 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 KRAS 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 KRAS 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F KRAS 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 KRAS 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 KRAS 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000019F055 KRAS 25416803 26968810 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000011A030 KRAS 25416803 25756961 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
PDE4DIP KRAS 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RBPMS KRAS 25348397 N/A physical interaction ComPPI
PIK3R2 KRAS 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HNRNPC KRAS 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TXNL4A KRAS 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDE6D KRAS 23698361 25348397 27898060 N/A physical interaction,amplified luminescent proximity homogeneous assay ComPPI,OmniPath
SORBS3 KRAS 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
KRAS EPB42 14525934 25348397 27898060 3276554 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
KRAS PIK3CG 10542052 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
KRAS SHOC2 10783161 14525934 25348397 9674433 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
KRAS RASSF5 11857081 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
KRAS RASGRP2 25348397 N/A in vitro,in vivo ComPPI
KRAS RAP1GDS1 11948427 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
KRAS RASSF2 12732644 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
KRAS RAF1 14525934 24234451 25348397 25852190 9446616 association anti tag coimmunoprecipitation,experimental interaction detection,fluorescent resonance energy transfer,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
KRAS PGGT1B 14525934 15451670 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
KRAS FNTA 12374986 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
KRAS FNTB 12374986 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
KRAS BCL2 10490827 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
KRAS PIK3CA 25348397 N/A physical interaction ComPPI
KRAS RALGDS 14525934 21988832 24234451 25348397 7809086 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,IntAct
KRAS RASGRF2 25348397 N/A physical interaction ComPPI
KRAS DNAJA3 25348397 N/A physical interaction ComPPI
KRAS CCT7 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KRAS EEF1A1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KRAS EEF1A1P5 25348397 N/A physical interaction ComPPI
KRAS IGSF21 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KRAS ELAVL1 25348397 N/A physical interaction ComPPI
KRAS APP 25348397 N/A physical interaction ComPPI
KRAS PHB 25348397 N/A physical interaction ComPPI
KRAS EGLN1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS LPAR1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS RGL2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KRAS ADH6 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS DDX47 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS DDX50 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS MAPK1 25348397 N/A physical interaction ComPPI
KRAS BTRC 25348397 N/A physical interaction ComPPI
KRAS ARAF 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KRAS MDFI 25348397 N/A physical interaction ComPPI
KRAS PSMA3 25348397 N/A physical interaction ComPPI
KRAS ZDHHC17 25348397 N/A two hybrid,physical interaction ComPPI
KRAS UNK 25348397 N/A physical interaction ComPPI
KRAS BCAS3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS CCL5 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS DIRAS3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS OSGIN1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS SERPINB5 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS THRSP 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS MOCS2 25348397 N/A physical interaction ComPPI
KRAS MOCS2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS MT-CO3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS MT-CYB 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS QDPR 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS TNFSF13 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS UQCRC1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRAS FRAT1 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
KRAS ZMYND8 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
KRAS LIMA1 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
KRAS PML 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
KRAS ABCD3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KRAS RPS29 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KRAS GOLIM4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KRAS MED4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KRAS GATAD2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KRAS NUP107 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KRAS TTC31 25348397 N/A physical interaction ComPPI
KRAS COPS7B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KRAS FAM83D 25348397 N/A physical interaction ComPPI
KRAS C1ORF131 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KRAS LSM11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KRAS PTGR2 25348397 N/A physical interaction ComPPI
KRAS TEDC1 25348397 N/A physical interaction ComPPI
KRAS NIBAN2 25348397 N/A physical interaction ComPPI
KRAS DUSP22 25348397 N/A physical interaction ComPPI
KRAS RIN1 25348397 N/A physical interaction ComPPI
KRAS BRAF 25348397 N/A physical interaction ComPPI
KRAS ARL6IP5 25348397 N/A physical interaction ComPPI
KRAS LYPD4 25348397 N/A physical interaction ComPPI
KRAS NDUFA13 25348397 N/A physical interaction ComPPI
KRAS RHOA 25348397 N/A physical interaction ComPPI
KRAS DEAF1 21900206 24234451 25348397 physical association two hybrid ComPPI,IntAct
KRAS CDK8 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
KRAS FANCC 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
KRAS FRAT2 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
KRAS HEMGN 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
KRAS IGFBP3 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
KRAS PPP2CB 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
KRAS STX17 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
KRAS ZNF189 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
KRAS NCBP2AS2 24234451 25348397 26496610 association anti tag coimmunoprecipitation ComPPI,IntAct
KRAS KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
TRAF6 KRAS 25348397 N/A physical interaction ComPPI
CALM1 KRAS 25348397 N/A physical interaction ComPPI
KRAS CALM2 11585916 12727204 14525934 N/A experimental interaction detection,two hybrid HPRD
SRC KRAS 27898060 9096340 stimulant N/A OmniPath
PRKCA KRAS 27898060 9922370 stimulant N/A OmniPath
KRAS TCF3 27898060 9528794 stimulant N/A OmniPath
KRAS MAP3K1 12228228 27898060 7744823 8649450 stimulant N/A OmniPath
KRAS APP 21832049 27898060 N/A N/A OmniPath
APP KRAS 21832049 27898060 N/A N/A OmniPath
KRAS BRAF 17635919 21779497 27898060 stimulant N/A OmniPath
LGALS3 KRAS 15205467 27898060 N/A N/A OmniPath
SOS1 KRAS 16293107 25624485 27898060 stimulant N/A OmniPath
PRKCQ KRAS 16483930 18182391 18458061 25713064 27898060 N/A N/A OmniPath
KRAS PIK3CA 21779497 27898060 stimulant N/A OmniPath
RIN1 KRAS 11784866 27898060 stimulant N/A OmniPath
RASSF5 KRAS 11857081 22195963 27898060 stimulant N/A OmniPath
KRAS RAF1 10783161 10882715 10958680 16041367 16093354 16293107 1629311 19029954 20080631 23153539 25852190 27898060 9446616 stimulant N/A OmniPath
RAF1 KRAS 10783161 10882715 10958680 16041367 16093354 1629311 19029954 20080631 23153539 25852190 27898060 9446616 N/A N/A OmniPath
KRAS RALGDS 10783161 21988832 27898060 7809086 stimulant N/A OmniPath
KRAS RASSF1 22195963 27898060 stimulant N/A OmniPath
DAB2IP KRAS 27858941 27898060 inhibition N/A OmniPath
KRAS RASSF2 12732644 27898060 N/A N/A OmniPath
KRAS PIK3CD 21779497 27898060 stimulant N/A OmniPath
KRAS PIK3CB 21779497 27898060 stimulant N/A OmniPath
SOS2 KRAS 21779497 27898060 stimulant N/A OmniPath
KRAS SHOC2 10783161 27898060 9674433 N/A N/A OmniPath
SHOC2 KRAS 10783161 27898060 9674433 stimulant N/A OmniPath
KRAS PIK3CG 10542052 21779497 27898060 9727023 stimulant N/A OmniPath
RASGEF1C KRAS 19201597 27898060 stimulant N/A OmniPath
RAP1GDS1 KRAS 11948427 20709748 21242305 27898060 stimulant N/A OmniPath
FNTB KRAS 12374986 24294527 27898060 stimulant N/A OmniPath
RAPGEF5 KRAS 19201597 27898060 stimulant N/A OmniPath
FNTA KRAS 12374986 24294527 27898060 stimulant N/A OmniPath
RASGEF1A KRAS 19201597 27898060 stimulant N/A OmniPath
RASGEF1B KRAS 19201597 27898060 stimulant N/A OmniPath

Visualization










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