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GENE：HDAC3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HDAC3
FullNmae histone deacetylase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4854
EnsembleID ENSG00000171720
Uniprot O15379

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HDAC3 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HDAC3 GO:0000118,GO:0000118,GO:0000122,GO:0000122,GO:0000132,GO:0001222,GO:0001701,GO:0001934,GO:0003682,GO:0003714,GO:0003714,GO:0004407,GO:0004407,GO:0004407,GO:0004407,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005794,GO:0005829,GO:0005886,GO:0006325,GO:0006366,GO:0006476,GO:0007346,GO:0016575,GO:0017053,GO:0019899,GO:0030332,GO:0031398,GO:0031490,GO:0031647,GO:0032008,GO:0032922,GO:0033558,GO:0033558,GO:0040014,GO:0042307,GO:0042752,GO:0042826,GO:0043066,GO:0045892,GO:0045944,GO:0046329,GO:0051059,GO:0051225,GO:0061436,GO:0071498,GO:0072686,GO:0120162,GO:0140297,GO:0140861,GO:0160008,GO:0160009,GO:0160010,GO:1903575,GO:2000726

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HDAC3 hsa:8841 path:hsa04613 Neutrophil extracellular trap formation - Homo sapiens (human)
HDAC3 hsa:8841 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)
HDAC3 hsa:8841 path:hsa05034 Alcoholism - Homo sapiens (human)
HDAC3 hsa:8841 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
HDAC1 HDAC3 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 26192618 9618481 interaction type N/A ACSN
HDAC3 SNAI2 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 26192618 9618481 interaction type N/A ACSN
HDAC3 NCOR1 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 interaction type N/A ACSN
HDAC3 TBL1X 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 interaction type N/A ACSN
HDAC3 TBL1XR1 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 interaction type N/A ACSN
HDAC3 PPARG 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 interaction type N/A ACSN
HDAC3 BMI1 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 26192618 9618481 interaction type N/A ACSN
HDAC3 MDM2 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 26192618 6396087 9450543 9618481 interaction type N/A ACSN
HDAC3 HDAC2 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 26192618 9618481 interaction type N/A ACSN
HDAC3 SIN3A 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 26192618 9618481 interaction type N/A ACSN
HDAC3 NOS2 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 interaction type N/A ACSN
HDAC3 CXCL10 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 interaction type N/A ACSN
HDAC3 SKI 12435627 19032343 23180781 26192618 association,physical association anti tag coimmunoprecipitation,tandem affinity purification ACSN,InnateDB
HDAC3 TAB2 12150997 23180781 physical association gst pull down InnateDB
TAB2 HDAC3 12150997 23180781 physical association affinity chromatography technology InnateDB
PPARG HDAC3 17015477 18619497 23180781 physical association anti tag coimmunoprecipitation InnateDB
HDAC3 BIRC3 15494311 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL8 HDAC3 15494311 23180781 physical association anti tag coimmunoprecipitation InnateDB
HDAC3 STAT1 16481475 23180781 physical association anti tag coimmunoprecipitation InnateDB
HDAC3 EMD 17620012 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL16 HDAC3 18097041 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
GABPA HDAC3 18097041 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A HDAC3 17273746 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD7 HDAC3 19032343 23180781 physical association anti tag coimmunoprecipitation InnateDB
IGHE HDAC3 20926124 23180781 physical association anti tag coimmunoprecipitation InnateDB
GATA3 HDAC3 17075044 23180781 physical association anti tag coimmunoprecipitation InnateDB
HDAC3 FUT7 17075044 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
TAB2 HDAC3 20005715 interaction type N/A PSP
NFKBIA HDAC3 20005715 interaction type N/A PSP
TAB2 HDAC3 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR HDAC3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 HDAC3 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC HDAC3 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 HDAC3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
HDAC4 HDAC3 11804585 trascriptional regulation,stimulation inferred by curator TFlink
YY1 HDAC3 19279113 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CSNK2A1 HDAC3 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
YY1 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 YY1 25361965 interaction type N/A PTMCode2
STAT3 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 STAT3 25361965 interaction type N/A PTMCode2
HIF1AN HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 HIF1AN 25361965 interaction type N/A PTMCode2
CTBP1 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 CTBP1 25361965 interaction type N/A PTMCode2
CBFA2T3 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 CBFA2T3 25361965 interaction type N/A PTMCode2
NACC1 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 NACC1 25361965 interaction type N/A PTMCode2
HDAC3 CSNK2A1 25361965 interaction type N/A PTMCode2
HDAC10 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 HDAC10 25361965 interaction type N/A PTMCode2
CCND1 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 CCND1 25361965 interaction type N/A PTMCode2
HDAC7 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 HDAC7 25361965 interaction type N/A PTMCode2
L3MBTL2 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 L3MBTL2 25361965 interaction type N/A PTMCode2
KAT2B HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 KAT2B 25361965 interaction type N/A PTMCode2
RUNX1 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 RUNX1 25361965 interaction type N/A PTMCode2
GCM1 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 GCM1 25361965 interaction type N/A PTMCode2
SAP30 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 SAP30 25361965 interaction type N/A PTMCode2
TP53 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 TP53 25361965 interaction type N/A PTMCode2
PRAM1 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 PRAM1 25361965 interaction type N/A PTMCode2
AKT1 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 AKT1 25361965 interaction type N/A PTMCode2
HDAC5 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 HDAC5 25361965 interaction type N/A PTMCode2
XPO1 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 XPO1 25361965 interaction type N/A PTMCode2
HDAC3 PPARD 25361965 interaction type N/A PTMCode2
PPARD HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 GPS2 25361965 interaction type N/A PTMCode2
GPS2 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 GTF2I 25361965 interaction type N/A PTMCode2
GTF2I HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 NRIP1 25361965 interaction type N/A PTMCode2
NRIP1 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 MAGEA2 25361965 interaction type N/A PTMCode2
MAGEA2 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 NR2C1 25361965 interaction type N/A PTMCode2
NR2C1 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 MAPK11 25361965 interaction type N/A PTMCode2
MAPK11 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 CORO2A 25361965 interaction type N/A PTMCode2
CORO2A HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 GATA2 25361965 interaction type N/A PTMCode2
GATA2 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 ARID4A 25361965 interaction type N/A PTMCode2
ARID4A HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 LCOR 25361965 interaction type N/A PTMCode2
LCOR HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 CDC16 25361965 interaction type N/A PTMCode2
CDC16 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 SMARCA4 25361965 interaction type N/A PTMCode2
SMARCA4 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 ZNF148 25361965 interaction type N/A PTMCode2
ZNF148 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 RBM15 25361965 interaction type N/A PTMCode2
RBM15 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 JUN 25361965 interaction type N/A PTMCode2
JUN HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 RBBP4 25361965 interaction type N/A PTMCode2
RBBP4 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 GATA1 25361965 interaction type N/A PTMCode2
GATA1 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 SUV39H1 25361965 interaction type N/A PTMCode2
SUV39H1 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 MYC 25361965 interaction type N/A PTMCode2
MYC HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 BCOR 25361965 interaction type N/A PTMCode2
BCOR HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 SKI 25361965 interaction type N/A PTMCode2
SKI HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 GATA3 25361965 interaction type N/A PTMCode2
GATA3 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 RBBP7 25361965 interaction type N/A PTMCode2
RBBP7 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 SAP18 25361965 interaction type N/A PTMCode2
SAP18 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 RELA 25361965 interaction type N/A PTMCode2
RELA HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 CEBPD 25361965 interaction type N/A PTMCode2
CEBPD HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 BRMS1 25361965 interaction type N/A PTMCode2
BRMS1 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 TBL1X 25361965 interaction type N/A PTMCode2
TBL1X HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 RXRA 25361965 interaction type N/A PTMCode2
RXRA HDAC3 25361965 interaction type N/A PTMCode2
CNOT2 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 CNOT2 25361965 interaction type N/A PTMCode2
PML HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 PML 25361965 interaction type N/A PTMCode2
NFKB1 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 NFKB1 25361965 interaction type N/A PTMCode2
HDAC4 HDAC3 25361965 interaction type N/A PTMCode2
HDAC3 HDAC4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIN1 HDAC3 21624135 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GEM HDAC3 16924111 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GOLGA2 HDAC3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NUDT21 HDAC3 25348397 N/A physical interaction ComPPI
PIAS2 HDAC3 12239342 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
NOS3 HDAC3 25348397 N/A physical interaction ComPPI
TFAP4 HDAC3 16924111 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
THAP7 HDAC3 25348397 N/A physical interaction ComPPI
DAXX HDAC3 25348397 N/A physical interaction,in vitro ComPPI
HSPA8 HDAC3 12502735 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SMYD1 HDAC3 11923873 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
GMNN HDAC3 25348397 N/A physical interaction ComPPI
RARA HDAC3 25348397 N/A physical interaction ComPPI
CCND1 HDAC3 12048199 14525934 16461912 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
STAT1 HDAC3 25348397 N/A physical interaction ComPPI
MAGEA2 HDAC3 16847267 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
NRIP1 HDAC3 11006275 14525934 17053781 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
EMD HDAC3 17620012 22570481 25348397 27898060 N/A physical interaction ComPPI,OmniPath
QPRT HDAC3 25348397 N/A physical interaction ComPPI
BRMS1 HDAC3 16919237 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SNAI1 HDAC3 24234451 25314079 25348397 deacetylation reaction physical interaction,deacetylase assay ComPPI,IntAct
DDX17 HDAC3 25348397 N/A physical interaction ComPPI
EGLN3 HDAC3 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
APPL1 HDAC3 23752268 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H4C1 HDAC3 25348397 N/A physical interaction ComPPI
TXNIP HDAC3 25348397 N/A physical interaction ComPPI
TLE1 HDAC3 21251616 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SYK HDAC3 25348397 N/A physical interaction ComPPI
EZH2 HDAC3 23079660 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SIAH2 HDAC3 25348397 N/A physical interaction ComPPI
SP1 HDAC3 25348397 N/A physical interaction ComPPI
PPP4C HDAC3 14525934 15805470 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
SMAD7 HDAC3 19032343 24234451 25348397 association physical interaction,chromatin immunoprecipitation assay ComPPI,IntAct
PIK3R1 HDAC3 25348397 N/A physical interaction ComPPI
SRC HDAC3 16532030 17699109 25348397 27898060 N/A physical interaction ComPPI,OmniPath
NFATC1 HDAC3 25348397 N/A physical interaction ComPPI
SPI1 HDAC3 25348397 N/A physical interaction ComPPI
PRKDC HDAC3 25348397 N/A physical interaction ComPPI
PRAM1 HDAC3 16432238 16730330 25348397 27898060 N/A physical interaction ComPPI,OmniPath
JUN HDAC3 12853483 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RB1 HDAC3 12479814 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
AR HDAC3 25348397 N/A physical interaction ComPPI
CREBBP HDAC3 14525934 16528103 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RUNX2 HDAC3 14525934 15292260 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SMARCD1 HDAC3 25348397 N/A physical interaction ComPPI
EP300 HDAC3 25348397 N/A physical interaction ComPPI
ATF3 HDAC3 25348397 N/A physical interaction ComPPI
HIF1A HDAC3 25348397 N/A physical interaction ComPPI
HDAC3 TBL1X 10809664 10944117 11931768 14525934 16980585 21258344 23752268 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
HDAC3 SUV39H1 11788710 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
HDAC3 YY1 11486036 14525934 17925399 18542060 18558095 18940814 19279113 25348397 27898060 9346952 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
HDAC3 PPARD 11867749 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HDAC3 NCOR2 11013263 16924111 16980585 21258344 21624135 22230954 23752268 24234451 24449765 25348397 association,physical association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,molecular sieving,x-ray crystallography,physical interaction,competition binding,deacetylase assay,in vitro ComPPI,IntAct
HDAC3 NCOR1 10944117 11013263 11466315 11509652 11804585 14525934 16917504 16980585 21258344 23752268 24234451 25348397 association,physical association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
HDAC3 NR2C1 11463856 12943985 14521922 14525934 19204783 21670149 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
HDAC3 GTF2I 12239342 12393887 14525934 25348397 N/A affinity chromatography technology,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
HDAC3 CORO2A 12628926 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
HDAC3 HR 11641275 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
HDAC3 XPO1 11779848 14525934 17141982 25348397 26673895 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
HDAC3 TNFRSF14 11463856 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
HDAC3 MAPK11 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
HDAC3 RBBP4 11470869 11777905 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
HDAC3 CBFA2T3 12242670 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HDAC3 TAB2 12150997 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HDAC3 HDAC4 10220385 11466315 14525934 17956988 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
HDAC3 HDAC9 10655483 11466315 12590135 14525934 25348397 N/A experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD
HDAC3 BCOR 10898795 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HDAC3 GTF2IRD1 12239342 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HDAC3 HSPA4 11777905 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HDAC3 HDAC7 11466315 14525934 23752268 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
HDAC3 HDAC5 10220385 11466315 11804585 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
HDAC3 EED 10581039 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
HDAC3 HDAC10 11861901 14525934 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
HDAC3 HIF1AN 11641274 14525934 24234451 25348397 26972000 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
HDAC3 GPS2 11931768 14525934 16980585 17895379 21258344 23752268 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
HDAC3 ANKRD11 14525934 15184363 23752268 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
HDAC3 CSNK2A1 14525934 15805470 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HDAC3 PML 11259576 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HDAC3 PPARG 12479814 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HDAC3 CCT5 12502735 14525934 23752268 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
HDAC3 BCL3 14525934 15469820 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HDAC3 PPP4R1 15805470 24234451 25348397 physical association anti tag coimmunoprecipitation,in vitro,in vivo ComPPI,IntAct
HDAC3 STAT3 14525934 15653507 18037959 22116549 25348397 25892518 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
HDAC3 KLF6 14525934 15917248 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
HDAC3 GCM1 14525934 16528103 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HDAC3 NACC1 14525934 16033423 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
HDAC3 MBD1 14525934 16432238 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
HDAC3 DHX30 14525934 17255935 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
HDAC3 NR2E3 14525934 17255935 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
HDAC3 PHB2 25348397 N/A physical interaction,in vitro ComPPI
HDAC3 GATA2 11567998 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
HDAC3 RUNX1T1 14525934 15333839 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HDAC3 RELA 11533489 12419806 14525934 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
HDAC3 ZBTB16 25348397 N/A physical interaction ComPPI
HDAC3 SF3B1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 CTBP1 25348397 N/A physical interaction ComPPI
HDAC3 GATA1 25348397 N/A physical interaction ComPPI
HDAC3 ZBTB33 25348397 N/A physical interaction ComPPI
HDAC3 RXRA 25348397 N/A physical interaction ComPPI
HDAC3 NR2C2 25348397 N/A physical interaction ComPPI
HDAC3 RBL1 25348397 N/A physical interaction ComPPI
HDAC3 VHL 25348397 N/A physical interaction ComPPI
HDAC3 IKZF1 25348397 N/A physical interaction ComPPI
HDAC3 THRA 25348397 N/A physical interaction ComPPI
HDAC3 SKI 19032343 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
HDAC3 AKT1 25348397 N/A physical interaction ComPPI
HDAC3 SMARCA4 25348397 N/A physical interaction ComPPI
HDAC3 DACH1 25348397 N/A physical interaction ComPPI
HDAC3 PAPOLA 25348397 N/A physical interaction ComPPI
HDAC3 KAT2B 25348397 N/A physical interaction ComPPI
HDAC3 MEF2D 25348397 N/A physical interaction ComPPI
HDAC3 SRF 25348397 N/A physical interaction ComPPI
HDAC3 ZFP36 25348397 N/A physical interaction ComPPI
HDAC3 ATXN3 25348397 N/A physical interaction ComPPI
HDAC3 GATA3 17075044 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 ZNF148 19583777 24234451 25348397 colocalization,association anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
HDAC3 EWSR1 25348397 N/A physical interaction ComPPI
HDAC3 PROX1 18948102 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 REPIN1 25348397 N/A physical interaction ComPPI
HDAC3 SAP30L 25348397 N/A physical interaction ComPPI
HDAC3 SAP30 25348397 N/A physical interaction ComPPI
HDAC3 CNOT2 16712523 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 RUNX1 25348397 N/A physical interaction ComPPI
HDAC3 RBM15 25348397 N/A physical interaction ComPPI
HDAC3 INSM1 25348397 N/A physical interaction ComPPI
HDAC3 CEBPD 25348397 N/A physical interaction ComPPI
HDAC3 NFKB1 25348397 N/A physical interaction ComPPI
HDAC3 CBFA2T2 25348397 N/A physical interaction ComPPI
HDAC3 PARP1 25348397 N/A physical interaction ComPPI
HDAC3 SAFB 25348397 N/A physical interaction ComPPI
HDAC3 SAFB2 25348397 N/A physical interaction ComPPI
HDAC3 LCOR 25348397 N/A physical interaction ComPPI
HDAC3 MYC 23079660 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction,chromatin immunoprecipitation assay ComPPI,IntAct
HDAC3 HNF4A 25348397 N/A physical interaction ComPPI
HDAC3 TMPO 16129885 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HDAC3 TMPO 25348397 N/A physical interaction ComPPI
HDAC3 KDM4A 25348397 N/A physical interaction ComPPI
HDAC3 NR0B2 17895379 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
HDAC3 ANKRD12 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 TBX3 25348397 N/A physical interaction ComPPI
HDAC3 MAFK 25348397 N/A physical interaction ComPPI
HDAC3 SRY 25348397 N/A physical interaction ComPPI
HDAC3 PBX1 25348397 N/A physical interaction ComPPI
HDAC3 IL16 25348397 N/A physical interaction ComPPI
HDAC3 ESR1 25348397 N/A physical interaction ComPPI
HDAC3 NR2E1 25348397 N/A physical interaction ComPPI
HDAC3 OVOL1 25348397 N/A physical interaction ComPPI
HDAC3 CREB3 25348397 N/A physical interaction ComPPI
HDAC3 BCL11B 17245431 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 THRB 25348397 N/A physical interaction ComPPI
HDAC3 L3MBTL2 20385135 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,fluorescence microscopy ComPPI,IntAct
HDAC3 NR1D1 20534529 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 PARP14 25348397 N/A physical interaction ComPPI
HDAC3 BRINP1 25348397 N/A physical interaction ComPPI
HDAC3 IRF3 25348397 N/A physical interaction ComPPI
HDAC3 MAPK14 25348397 N/A physical interaction ComPPI
HDAC3 CCN5 25348397 N/A physical interaction ComPPI
HDAC3 NONO 25348397 N/A physical interaction ComPPI
HDAC3 TWIST1 25348397 N/A physical interaction ComPPI
HDAC3 E2F4 25348397 N/A physical interaction ComPPI
HDAC3 NRDC 25348397 N/A physical interaction ComPPI
HDAC3 DNMT1 25348397 N/A physical interaction ComPPI
HDAC3 KDM1A 21258344 23752268 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
HDAC3 KDM4C 25348397 N/A physical interaction ComPPI
HDAC3 DDX5 25348397 N/A physical interaction ComPPI
HDAC3 TOP2B 25348397 N/A physical interaction ComPPI
HDAC3 TUBA1A 25348397 N/A physical interaction ComPPI
HDAC3 CHD3 25348397 N/A physical interaction ComPPI
HDAC3 ZMYM3 21258344 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 ZBTB7B 25348397 N/A physical interaction ComPPI
HDAC3 TRIM28 25348397 N/A physical interaction ComPPI
HDAC3 RREB1 23752268 24234451 25348397 colocalization,association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
HDAC3 RCOR1 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 RCOR3 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 CCT2 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 CCT4 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 CCT7 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 CCT3 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 CCT8 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 CCT6A 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 PRDM6 25348397 N/A physical interaction ComPPI
HDAC3 NFE2L2 25348397 N/A physical interaction ComPPI
HDAC3 MEF2A 25348397 N/A physical interaction ComPPI
HDAC3 APEX1 25348397 N/A physical interaction ComPPI
HDAC3 SREBF2 25348397 N/A physical interaction ComPPI
HDAC3 H2AC1 25348397 N/A physical interaction ComPPI
HDAC3 H2BC1 25348397 N/A physical interaction ComPPI
HDAC3 RFPL4B 25348397 N/A physical interaction ComPPI
HDAC3 CARD8 25348397 N/A physical interaction ComPPI
HDAC3 LIPH 25348397 N/A physical interaction ComPPI
HDAC3 PPAT 25348397 N/A physical interaction ComPPI
HDAC3 KAT5 25348397 N/A physical interaction ComPPI
HDAC3 PPP1CA 25348397 N/A physical interaction ComPPI
HDAC3 NINL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HDAC3 SEC16A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 CCDC88A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 DCAF1 25348397 N/A physical interaction ComPPI
HDAC3 DDB1 25348397 N/A physical interaction ComPPI
HDAC3 BCL6 25348397 N/A physical interaction ComPPI
HDAC3 TBL1Y 25348397 N/A physical interaction ComPPI
HDAC3 ZSCAN5A 25348397 N/A physical interaction ComPPI
HDAC3 HNRNPLL 25348397 N/A physical interaction ComPPI
HDAC3 CELA1 25348397 N/A physical interaction ComPPI
HDAC3 AK9 25348397 N/A physical interaction ComPPI
HDAC3 F9 25348397 N/A physical interaction ComPPI
HDAC3 TRMT1 25348397 N/A physical interaction ComPPI
HDAC3 LYZL1 25348397 N/A physical interaction ComPPI
HDAC3 ODAPH 25348397 N/A physical interaction ComPPI
HDAC3 IL17RA 25348397 N/A physical interaction ComPPI
HDAC3 C6ORF141 25348397 N/A physical interaction ComPPI
HDAC3 SIRT6 25348397 N/A physical interaction ComPPI
HDAC3 USP44 25348397 N/A physical interaction ComPPI
HDAC3 BUB1B 19407811 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 FOXK2 25348397 N/A physical interaction ComPPI
HDAC3 TP53 10777477 14525934 16847267 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
HDAC3 PGK1 24234451 25348397 26356530 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
HDAC3 MECP2 23770565 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC3 PCIF1 17126328 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HDAC3 LIN54 17531812 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HDAC3 BAG1 19595997 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HDAC3 TLE5 21251616 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
HDAC3 RBPJ 21475249 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
HDAC3 YWHAE 21624135 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HDAC3 WWOX 24234451 25348397 25678599 physical association anti tag coimmunoprecipitation ComPPI,IntAct
HDAC3 SUZ12 23079660 24234451 25348397 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
HDAC3 PRMT5 19032343 24234451 25348397 association cosedimentation through density gradient ComPPI,IntAct
HDAC3 AKAP8L 16980585 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
HDAC3 AKAP8 16980585 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,molecular sieving,confocal microscopy ComPPI,IntAct
HDAC3 AURKB 16980585 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
NFKBIA HDAC3 12972430 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PKM HDAC3 25348397 N/A anti tag coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI
YWHAQ HDAC3 25348397 N/A physical interaction ComPPI
SOX2 HDAC3 25348397 N/A physical interaction ComPPI
TCP1 HDAC3 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ZBTB7A HDAC3 25348397 N/A physical interaction ComPPI
ETV6 HDAC3 25348397 N/A physical interaction ComPPI
H3C1 HDAC3 25348397 N/A physical interaction ComPPI
ANKRA2 HDAC3 25348397 N/A physical interaction ComPPI
TBL1XR1 HDAC3 11931768 14525934 21258344 23752268 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
WDR5 HDAC3 25348397 N/A physical interaction ComPPI
THAP11 HDAC3 14525934 18585351 24234451 25348397 physical association experimental interaction detection,pull down,in vitro ComPPI,HPRD,IntAct
PRDM4 HDAC3 25348397 N/A physical interaction ComPPI
MAGEB2 HDAC3 25348397 N/A physical interaction ComPPI
HDAC3 ARID4A 10490602 14525934 N/A experimental interaction detection HPRD
HDAC3 HDAC1 10944117 11302704 14525934 N/A experimental interaction detection HPRD
HDAC3 HDAC3 10655483 10898795 11779848 11804585 14521922 14525934 22230954 24234451 N/A experimental interaction detection,molecular sieving HPRD,IntAct
HDAC3 SMYD4 18714374 27898060 N/A N/A OmniPath
HDAC3 CDKN1A 16533812 27898060 inhibition,stimulant N/A OmniPath
CHUK HDAC3 15494311 16382138 27898060 N/A N/A OmniPath
HDAC3 H4C1 15832170 17694085 24722339 27898060 inhibition,stimulant N/A OmniPath
NCOR2 HDAC3 10809664 10860984 10944117 11013263 11509652 11804585 12205093 12502735 12628926 14527417 15837933 16481466 16924111 17126328 17694085 21258344 21624135 22230954 23752268 27898060 stimulant N/A OmniPath
AKAP8 HDAC3 16980585 27898060 stimulant N/A OmniPath
HDAC3 H3C1 16865259 19442252 27898060 inhibition N/A OmniPath
HDAC3 STAT1 16481475 27898060 N/A N/A OmniPath
BCL3 HDAC3 15469820 20547759 27898060 stimulant N/A OmniPath
HDAC3 TRIM28 18037959 27898060 stimulant N/A OmniPath
HDAC3 E2F1 23213415 27898060 stimulant N/A OmniPath
HDAC3 HDAC1 10944117 11302704 23213415 27898060 stimulant N/A OmniPath
HDAC3 NFE2L2 18241676 27898060 inhibition N/A OmniPath
TAB2 HDAC3 12150997 27898060 N/A N/A OmniPath
HDAC3 RELA 11533489 12419806 15192014 27898060 inhibition N/A OmniPath
CSNK2A1 HDAC3 15805470 18452278 21624135 26356530 27898060 stimulant N/A OmniPath
CCND1 HDAC3 12048199 15558026 15713663 16461912 20484017 27898060 stimulant N/A OmniPath
HDAC3 HIF1A 11641274 17273746 27898060 N/A N/A OmniPath
HDAC3 MAFK 18241676 27898060 inhibition N/A OmniPath
NCOR1 HDAC3 10860984 10944117 11013263 11466315 11509652 11804585 11931768 12628926 14527417 14722073 15601853 16195251 16469706 16917504 17694085 21258344 23752268 27898060 stimulant N/A OmniPath
HDAC3 SMAD7 15831498 15831516 23213415 27898060 stimulant N/A OmniPath
PPP4C HDAC3 15805470 27898060 inhibition N/A OmniPath
HDAC3 PAG1 18241676 27898060 inhibition N/A OmniPath
BCOR HDAC3 10898795 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009BA57A HDAC3 27087310 direct interaction,inhibition N/A NPInter

Visualization










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