Gene Information gene info

  1. Home

GENE：PSMB5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSMB5
FullNmae proteasome 20S subunit beta 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9542
EnsembleID ENSG00000100804
Uniprot P28074

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSMB5 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMB5 apoptosis 29365400 The expression of PSMB5 was negatively correlated with the apoptosis of RPMI 8226 and BTZ100 under the treatment of BTZ. retulator signature
PSMB5 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
PSMB5 GO:0000502,GO:0000502,GO:0004175,GO:0004298,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005813,GO:0005829,GO:0005839,GO:0005839,GO:0006508,GO:0006979,GO:0008233,GO:0010498,GO:0019774,GO:0019774,GO:0043161,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSMB5 hsa:5693 path:hsa03050 Proteasome - Homo sapiens (human)
PSMB5 hsa:5693 path:hsa05010 Alzheimer disease - Homo sapiens (human)
PSMB5 hsa:5693 path:hsa05012 Parkinson disease - Homo sapiens (human)
PSMB5 hsa:5693 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
PSMB5 hsa:5693 path:hsa05016 Huntington disease - Homo sapiens (human)
PSMB5 hsa:5693 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
PSMB5 hsa:5693 path:hsa05020 Prion disease - Homo sapiens (human)
PSMB5 hsa:5693 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PSMB5 ELP1 18303054 23180781 physical association anti tag coimmunoprecipitation InnateDB
PSMB5 TRAF6 14743216 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PSMB5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PSMB5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PSMB5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PSMB5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PSMB5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PSMB5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 PSMB5 24627483 trascriptional regulation,stimulation inferred by curator TFlink
MYC PSMB5 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001E0AEA PSMB5 17612493 22473208 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS000035CC3E PSMB5 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000BE495 PSMB5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001DE669 PSMB5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000170CF4 PSMB5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004407DC PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000045147B PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005CE28 PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEF5F PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000345DEB PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000023F8DA PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004AE8D3 PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CF1D2 PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000A9FB9 PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000057A7C PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000047944F PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000224AEA PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 PSMB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D PSMB5 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 PSMB5 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C PSMB5 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000302909 PSMB5 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000B59A2 PSMB5 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000F31F4 PSMB5 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TCHP PSMB5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMB10 PSMB5 25348397 N/A physical interaction ComPPI
GET3 PSMB5 25348397 N/A physical interaction ComPPI
BAG3 PSMB5 25348397 N/A physical interaction ComPPI
VIM PSMB5 25348397 N/A physical interaction ComPPI
SNRPA1 PSMB5 25348397 N/A physical interaction ComPPI
PSMC3 PSMB5 25348397 N/A physical interaction ComPPI
PSMC6 PSMB5 25348397 N/A physical interaction ComPPI
KIF5B PSMB5 25348397 N/A physical interaction ComPPI
PSMD14 PSMB5 25348397 N/A physical interaction ComPPI
TRAF6 PSMB5 14525934 14743216 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
PSMD7 PSMB5 25348397 N/A physical interaction ComPPI
LSM1 PSMB5 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
RAN PSMB5 25348397 N/A physical interaction ComPPI
SKP1 PSMB5 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
BMI1 PSMB5 25348397 N/A physical interaction ComPPI
GCSH PSMB5 25348397 N/A physical interaction ComPPI
MCM2 PSMB5 25348397 N/A physical interaction ComPPI
PSMB2 PSMB5 14733938 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HSP90AB1 PSMB5 16263121 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DDIT4L PSMB5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AP3M1 PSMB5 25348397 N/A physical interaction ComPPI
PIK3R1 PSMB5 14525934 18711014 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
JUN PSMB5 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
USP7 PSMB5 25348397 N/A physical interaction ComPPI
PSMA3 PSMB5 14525934 14733938 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMD11 PSMB5 25348397 N/A physical interaction ComPPI
TAP2 PSMB5 14525934 15488952 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
TAP1 PSMB5 14525934 15488952 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
PDIA3 PSMB5 25348397 N/A physical interaction ComPPI
ACTN4 PSMB5 25348397 N/A physical interaction ComPPI
UBC PSMB5 25348397 N/A physical interaction ComPPI
HSP90AA1 PSMB5 25348397 N/A physical interaction ComPPI
CANX PSMB5 17948026 24234451 25348397 colocalization cosedimentation through density gradient ComPPI,IntAct
YBX1 PSMB5 25348397 N/A physical interaction ComPPI
PLK1 PSMB5 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PSMA1 PSMB5 12376572 14525934 14733938 24234451 25348397 25599644 association,physical association affinity chromatography technology,two hybrid,x-ray crystallography,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMA6 PSMB5 17948026 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA5 PSMB5 25348397 N/A physical interaction ComPPI
PSMB9 PSMB5 25348397 N/A physical interaction ComPPI
MYC PSMB5 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CFTR PSMB5 25348397 N/A physical interaction ComPPI
PSMD8 PSMB5 25348397 N/A physical interaction ComPPI
ACTN2 PSMB5 25348397 N/A physical interaction ComPPI
PSMB8 PSMB5 25348397 N/A physical interaction ComPPI
PSMD1 PSMB5 25348397 N/A physical interaction ComPPI
RDX PSMB5 25348397 N/A physical interaction ComPPI
PSMC5 PSMB5 25348397 N/A physical interaction ComPPI
RAD23A PSMB5 25348397 N/A physical interaction ComPPI
EPB41L1 PSMB5 25348397 N/A physical interaction ComPPI
CUL1 PSMB5 25348397 N/A physical interaction ComPPI
VHL PSMB5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMC4 PSMB5 25348397 N/A physical interaction ComPPI
PINX1 PSMB5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MAP1LC3A PSMB5 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
HSPH1 PSMB5 25348397 N/A physical interaction ComPPI
AURKA PSMB5 25348397 N/A physical interaction ComPPI
RIPK2 PSMB5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
BAG4 PSMB5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMD2 PSMB5 25348397 N/A physical interaction ComPPI
MID1 PSMB5 25348397 N/A physical interaction ComPPI
MID2 PSMB5 25348397 N/A physical interaction ComPPI
PRKN PSMB5 25348397 N/A physical interaction ComPPI
HDAC5 PSMB5 25348397 N/A physical interaction ComPPI
PSMD4 PSMB5 25348397 N/A physical interaction ComPPI
XRN1 PSMB5 25348397 N/A physical interaction ComPPI
FKBP8 PSMB5 25348397 N/A physical interaction ComPPI
BUB1B PSMB5 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB5 ABCB5 14525934 15488952 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
PSMB5 PSMA2 14525934 14733938 15887188 24234451 25348397 association anti bait coimmunoprecipitation,two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMB5 PSMB7 14525934 14733938 17948026 20723761 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMB5 POMP 14525934 14733938 17948026 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMB5 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB5 UCHL5 18922472 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB5 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB5 SLX1A 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB5 TERF1 25348397 N/A physical interaction ComPPI
PSMB5 PSMA4 25348397 N/A physical interaction ComPPI
PSMB5 RND1 25348397 N/A physical interaction ComPPI
PSMB5 PSMC1 25348397 N/A physical interaction ComPPI
PSMB5 PSMC2 22901813 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB5 UBE2C 25348397 N/A physical interaction ComPPI
PSMB5 PSMB6 25348397 N/A physical interaction ComPPI
PSMB5 PSMA7 25348397 N/A physical interaction ComPPI
PSMB5 PSMD12 25348397 N/A physical interaction ComPPI
PSMB5 PSMD13 25348397 N/A physical interaction ComPPI
PSMB5 PSMD3 25348397 N/A physical interaction ComPPI
PSMB5 PSME2 25348397 N/A physical interaction ComPPI
PSMB5 PSMD5 25348397 N/A physical interaction ComPPI
PSMB5 PSMA8 25348397 N/A physical interaction ComPPI
PSMB5 ELP1 25348397 N/A physical interaction ComPPI
PSMB5 HSP90AA2P 25348397 N/A physical interaction ComPPI
PSMB5 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
PSMB5 IQCB1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB5 CDKL1 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PSMB5 CDK20 25348397 N/A physical interaction ComPPI
PSMB5 CAST 25348397 N/A physical interaction ComPPI
PSMB5 RPP38 25348397 N/A physical interaction ComPPI
PSMB5 PYCR3 25348397 N/A physical interaction ComPPI
PSMB5 PSMG3 25348397 N/A physical interaction ComPPI
PSMB5 MOV10 25348397 N/A physical interaction ComPPI
PSMB5 NXF1 25348397 N/A physical interaction ComPPI
PSMB5 AMFR 25348397 N/A physical interaction ComPPI
PSMB5 AMBRA1 25348397 N/A physical interaction ComPPI
PSMB5 CPSF2 25348397 N/A physical interaction ComPPI
PSMB5 ELP6 25348397 N/A physical interaction ComPPI
PSMB5 PSMG2 25348397 N/A physical interaction ComPPI
PSMB5 PYGL 25348397 N/A physical interaction ComPPI
PSMB5 CEP85 25348397 N/A physical interaction ComPPI
PSMB5 FBXO7 25348397 N/A physical interaction ComPPI
PSMB5 CYLD 25348397 N/A physical interaction ComPPI
PSMB5 BRCA1 25348397 N/A physical interaction ComPPI
PSMB5 FTSJ1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB5 TMBIM4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB5 EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB5 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PSMB5 L3MBTL1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PSMB5 L3MBTL4 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PSMB5 NTAQ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMB5 DUSP29 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMB5 IKBKG 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMB4 PSMB5 17948026 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PSMB1 PSMB5 14525934 14733938 17948026 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMB3 PSMB5 14525934 14733938 17948026 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ADRM1 PSMB5 25348397 N/A physical interaction ComPPI
TRAF6 PSMB5 14743216 17353931 27898060 N/A N/A OmniPath

Visualization










  Return