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GENE：PSMD1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSMD1
FullNmae proteasome 26S subunit, non-ATPase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9554
EnsembleID ENSG00000173692
Uniprot Q99460

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSMD1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMD1 apoptosis 33712704 Knockdown of PSMD1 or PSMD3 protein correlated with reduced survival and increased apoptosis in CML cells, but not in normal cord blood CD34+ progenitors. retulator signature

Go Annotation:

GeneSymbol Go id
PSMD1 GO:0000502,GO:0000502,GO:0005515,GO:0005576,GO:0005634,GO:0005654,GO:0005829,GO:0005838,GO:0008540,GO:0016020,GO:0022624,GO:0030234,GO:0031625,GO:0034515,GO:0035578,GO:0042176,GO:0043161,GO:0043161

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSMD1 hsa:5707 path:hsa03050 Proteasome - Homo sapiens (human)
PSMD1 hsa:5707 path:hsa05010 Alzheimer disease - Homo sapiens (human)
PSMD1 hsa:5707 path:hsa05012 Parkinson disease - Homo sapiens (human)
PSMD1 hsa:5707 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
PSMD1 hsa:5707 path:hsa05016 Huntington disease - Homo sapiens (human)
PSMD1 hsa:5707 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
PSMD1 hsa:5707 path:hsa05020 Prion disease - Homo sapiens (human)
PSMD1 hsa:5707 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
PSMD1 hsa:5707 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PSMD1 PTGS2 17429597 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRAF6 PSMD1 14743216 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR PSMD1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 PSMD1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PSMD1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 PSMD1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PSMD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PSMD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PSMD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PSMD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PSMD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PSMD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PSMD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PSMD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000079D48 PSMD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BE495 PSMD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000134ADC PSMD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC PSMD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D PSMD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE PSMD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 PSMD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA PSMD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E PSMD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D PSMD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 PSMD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001B12A4 PSMD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 PSMD1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PSMA4 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMA4 25361965 interaction type N/A PTMCode2
PSMA6 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMA6 25361965 interaction type N/A PTMCode2
PSMC4 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMC4 25361965 interaction type N/A PTMCode2
PSMD6 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMD6 25361965 interaction type N/A PTMCode2
PSMD8 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMD8 25361965 interaction type N/A PTMCode2
USP14 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 USP14 25361965 interaction type N/A PTMCode2
PSMD1 PSMA1 25361965 interaction type N/A PTMCode2
PSMA1 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 RAD23B 25361965 interaction type N/A PTMCode2
RAD23B PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMB10 25361965 interaction type N/A PTMCode2
PSMB10 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PIPSL 25361965 interaction type N/A PTMCode2
PIPSL PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMD14 25361965 interaction type N/A PTMCode2
PSMD14 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMB9 25361965 interaction type N/A PTMCode2
PSMB9 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMC6 25361965 interaction type N/A PTMCode2
PSMC6 PSMD1 25361965 interaction type N/A PTMCode2
PSMC1 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMC1 25361965 interaction type N/A PTMCode2
PSMB6 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMB6 25361965 interaction type N/A PTMCode2
CD68 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 CD68 25361965 interaction type N/A PTMCode2
PSMA5 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMA5 25361965 interaction type N/A PTMCode2
PSMD11 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMD11 25361965 interaction type N/A PTMCode2
PSMB7 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMB7 25361965 interaction type N/A PTMCode2
PSMD5 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMD5 25361965 interaction type N/A PTMCode2
PSMD7 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMD7 25361965 interaction type N/A PTMCode2
PSMA3 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMA3 25361965 interaction type N/A PTMCode2
PSMD10 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMD10 25361965 interaction type N/A PTMCode2
RPS27A PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 RPS27A 25361965 interaction type N/A PTMCode2
PSMC3 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMC3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNW1 PSMD1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L PSMD1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NPM1 PSMD1 25348397 N/A physical interaction ComPPI
RPS28 PSMD1 25348397 N/A physical interaction ComPPI
PSMC3 PSMD1 25348397 N/A physical interaction ComPPI
PSMC6 PSMD1 19490896 24234451 25348397 physical association cosedimentation in solution,physical interaction ComPPI,IntAct
SNAI2 PSMD1 25348397 N/A physical interaction ComPPI
PSMD14 PSMD1 19615732 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRAF6 PSMD1 14525934 14743216 24234451 25348397 physical association experimental interaction detection,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
PSMD7 PSMD1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GABARAPL2 PSMD1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PPFIA1 PSMD1 25348397 N/A physical interaction ComPPI
PTPN6 PSMD1 25348397 N/A pull down ComPPI
PSMB2 PSMD1 25348397 N/A physical interaction ComPPI
HSP90AB1 PSMD1 16263121 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SMAD1 PSMD1 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
RACGAP1 PSMD1 25348397 N/A physical interaction ComPPI
ABRAXAS2 PSMD1 19214193 24234451 25348397 association biochemical ComPPI,IntAct
JUN PSMD1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
CPNE1 PSMD1 25348397 N/A physical interaction ComPPI
PSMA3 PSMD1 25348397 N/A physical interaction ComPPI
PSMD11 PSMD1 25348397 N/A physical interaction ComPPI
CUL3 PSMD1 25348397 N/A physical interaction ComPPI
YWHAZ PSMD1 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
TUBA1B PSMD1 25348397 N/A physical interaction ComPPI
CAPN3 PSMD1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
UBC PSMD1 25348397 N/A physical interaction ComPPI
HSP90AA1 PSMD1 25348397 N/A physical interaction ComPPI
NTRK1 PSMD1 25348397 N/A physical interaction ComPPI
APC PSMD1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
BAG1 PSMD1 25348397 N/A physical interaction,in vivo ComPPI
PTPN2 PSMD1 25348397 N/A physical interaction ComPPI
HSPA5 PSMD1 25348397 N/A physical interaction ComPPI
PSMA1 PSMD1 25348397 N/A physical interaction ComPPI
PSMA6 PSMD1 25348397 N/A physical interaction ComPPI
PSMA5 PSMD1 25348397 N/A physical interaction ComPPI
PSMB9 PSMD1 25348397 N/A physical interaction ComPPI
EEF1A1 PSMD1 25348397 N/A physical interaction ComPPI
TUBA4A PSMD1 25348397 N/A physical interaction ComPPI
HNRNPL PSMD1 25348397 N/A physical interaction ComPPI
PPARG PSMD1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
CAD PSMD1 25348397 N/A physical interaction ComPPI
CFTR PSMD1 25348397 N/A physical interaction ComPPI
GSK3A PSMD1 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MAPK6 PSMD1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
PPP2CA PSMD1 25348397 N/A physical interaction ComPPI
PSMD8 PSMD1 25348397 N/A physical interaction ComPPI
CILK1 PSMD1 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PSMB8 PSMD1 25348397 N/A physical interaction ComPPI
PSMD1 PSMD13 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD1 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD1 PSMD10 17353931 19490896 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD1 PAAF1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD1 PSMC4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD1 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD1 PSMC5 18922472 19490896 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD1 UCHL5 18922472 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD1 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD1 PTGS2 25348397 N/A physical interaction ComPPI
PSMD1 MDM2 25348397 N/A physical interaction ComPPI
PSMD1 HDAC5 25348397 N/A physical interaction ComPPI
PSMD1 SEM1 25348397 N/A physical interaction ComPPI
PSMD1 PSMC2 25348397 N/A physical interaction ComPPI
PSMD1 PSMD4 16990800 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD1 PSMA7 25348397 N/A physical interaction ComPPI
PSMD1 RANBP2 25348397 N/A physical interaction ComPPI
PSMD1 RAD23A 16712842 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
PSMD1 SIRT7 25348397 N/A physical interaction ComPPI
PSMD1 FKBP8 25348397 N/A physical interaction ComPPI
PSMD1 PSMC1 19490896 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,cosedimentation in solution,physical interaction ComPPI,IntAct
PSMD1 PSMD5 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD1 STUB1 25348397 N/A physical interaction ComPPI
PSMD1 PINK1 25348397 N/A physical interaction ComPPI
PSMD1 PSMA2 25348397 N/A physical interaction ComPPI
PSMD1 RAD23B 16712842 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
PSMD1 PSMD12 25348397 N/A physical interaction ComPPI
PSMD1 PSMD2 25348397 N/A physical interaction ComPPI
PSMD1 PSMD3 25348397 N/A physical interaction ComPPI
PSMD1 PSMB7 20723761 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD1 PSMB5 25348397 N/A physical interaction ComPPI
PSMD1 PSMA4 25348397 N/A physical interaction ComPPI
PSMD1 PSMB6 25348397 N/A physical interaction ComPPI
PSMD1 PSME1 25348397 N/A physical interaction ComPPI
PSMD1 PSME2 25348397 N/A physical interaction ComPPI
PSMD1 PSME3 25348397 N/A physical interaction ComPPI
PSMD1 ECD 25348397 N/A physical interaction ComPPI
PSMD1 SF3A1 25348397 N/A physical interaction ComPPI
PSMD1 ACTR1A 25348397 N/A physical interaction ComPPI
PSMD1 DCTN2 25348397 N/A physical interaction ComPPI
PSMD1 SEC24A 25348397 N/A physical interaction ComPPI
PSMD1 RBM12 25348397 N/A physical interaction ComPPI
PSMD1 SEC24C 25348397 N/A physical interaction ComPPI
PSMD1 SDHA 25348397 N/A physical interaction ComPPI
PSMD1 TPM4 25348397 N/A physical interaction ComPPI
PSMD1 TUBA1A 25348397 N/A physical interaction ComPPI
PSMD1 EPAS1 25348397 N/A physical interaction ComPPI
PSMD1 HSP90AA2P 25348397 N/A physical interaction ComPPI
PSMD1 PRKN 25348397 N/A physical interaction ComPPI
PSMD1 HDAC6 25348397 N/A physical interaction ComPPI
PSMD1 RNF11 25348397 N/A physical interaction ComPPI
PSMD1 CDK11B 25348397 N/A physical interaction ComPPI
PSMD1 CDK11A 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PSMD1 CDK20 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PSMD1 RPS12 25348397 N/A physical interaction ComPPI
PSMD1 RPS21 25348397 N/A physical interaction ComPPI
PSMD1 TXNL1 25348397 N/A physical interaction ComPPI
PSMD1 RPS15A 25348397 N/A physical interaction ComPPI
PSMD1 RPS8 25348397 N/A physical interaction ComPPI
PSMD1 HUWE1 25348397 N/A physical interaction ComPPI
PSMD1 MOV10 25348397 N/A physical interaction ComPPI
PSMD1 NXF1 25348397 N/A physical interaction ComPPI
PSMD1 CCDC8 25348397 N/A physical interaction ComPPI
PSMD1 EGFR 25348397 N/A physical interaction ComPPI
PSMD1 SYVN1 25348397 N/A physical interaction ComPPI
PSMD1 ABCE1 25348397 N/A physical interaction ComPPI
PSMD1 ESR1 24234451 25348397 25604459 association physical interaction,tandem affinity purification ComPPI,IntAct
PSMD1 CCDC74B 25348397 N/A physical interaction ComPPI
PSMD1 HSPB1 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
PSMD1 PSMA8 25348397 N/A physical interaction ComPPI
PSMD1 EEF1A1P5 25348397 N/A physical interaction ComPPI
PSMD1 ZNF24 25348397 N/A physical interaction ComPPI
PSMD1 PSMD9 25348397 N/A physical interaction ComPPI
PSMD1 HERC2 25348397 N/A physical interaction ComPPI
PSMD1 HERC2P3 25348397 N/A physical interaction ComPPI
PSMD1 TMEM67 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PSMD1 CRY2 25348397 N/A physical interaction ComPPI
PSMD1 DERL1 25348397 N/A physical interaction ComPPI
PSMD1 CCDC92 25348397 N/A physical interaction ComPPI
PSMD1 CYLD 25348397 N/A physical interaction ComPPI
PSMD1 HSD17B10 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PSMD1 EDEM3 25348397 N/A physical interaction ComPPI
PSMD1 TRIM25 25348397 N/A physical interaction ComPPI
PSMD1 BRCA1 25348397 N/A physical interaction ComPPI
PSMD1 CD40 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD1 TFE3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD1 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD1 TNFRSF10D 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD1 BCAR3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD1 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD1 PRKAB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD1 ESR2 21182203 24234451 25348397 25604459 association affinity chromatography technology,tandem affinity purification ComPPI,IntAct
PSMD1 PTP4A1 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
SEM1 PSMD1 25348397 N/A physical interaction ComPPI
PSMB4 PSMD1 25348397 N/A physical interaction ComPPI
PSMB1 PSMD1 25348397 N/A physical interaction ComPPI
PSMB3 PSMD1 25348397 N/A physical interaction ComPPI
EEF1A2 PSMD1 25348397 N/A physical interaction ComPPI
ADRM1 PSMD1 14525934 16501559 16906146 16990800 18497817 18497827 24234451 25348397 N/A two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
UBLCP1 PSMD1 25348397 N/A physical interaction ComPPI
ECPAS PSMD1 25348397 N/A physical interaction ComPPI
PSMD1 ALPK3 24234451 30021884 physical association cross-linking study IntAct
PSMD1 MBD4 24234451 30021884 physical association cross-linking study IntAct
L1TD1 PSMD1 24234451 25702638 association anti bait coimmunoprecipitation IntAct
TRAF6 PSMD1 14743216 27898060 N/A N/A OmniPath

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