Gene Information gene info

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GENE：PSMD8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSMD8
FullNmae proteasome 26S subunit, non-ATPase 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9566
EnsembleID ENSG00000099341
Uniprot P48556

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSMD8 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMD8 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PSMD8 GO:0000502,GO:0000502,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005829,GO:0005838,GO:0008541,GO:0008541,GO:0022624,GO:0043161,GO:0043161

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSMD8 hsa:5714 path:hsa03050 Proteasome - Homo sapiens (human)
PSMD8 hsa:5714 path:hsa05010 Alzheimer disease - Homo sapiens (human)
PSMD8 hsa:5714 path:hsa05012 Parkinson disease - Homo sapiens (human)
PSMD8 hsa:5714 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
PSMD8 hsa:5714 path:hsa05016 Huntington disease - Homo sapiens (human)
PSMD8 hsa:5714 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
PSMD8 hsa:5714 path:hsa05020 Prion disease - Homo sapiens (human)
PSMD8 hsa:5714 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
PSMD8 hsa:5714 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PSMD8 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 PSMD8 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 PSMD8 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PSMD8 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PSMD8 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PSMD8 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PSMD8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PSMD8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC PSMD8 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000048BA36 PSMD8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 PSMD8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE PSMD8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BE495 PSMD8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 PSMD8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D PSMD8 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PSMA4 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 PSMA4 25361965 interaction type N/A PTMCode2
PSMD8 PSMA3 25361965 interaction type N/A PTMCode2
PSMA3 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 PSMD10 25361965 interaction type N/A PTMCode2
PSMD10 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 PSMD7 25361965 interaction type N/A PTMCode2
PSMD7 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 PSMC1 25361965 interaction type N/A PTMCode2
PSMC1 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 USP14 25361965 interaction type N/A PTMCode2
USP14 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 PSMD11 25361965 interaction type N/A PTMCode2
PSMD11 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 NOB1 25361965 interaction type N/A PTMCode2
NOB1 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 PSMA5 25361965 interaction type N/A PTMCode2
PSMA5 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 PSMC3 25361965 interaction type N/A PTMCode2
PSMC3 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 PSMA1 25361965 interaction type N/A PTMCode2
PSMA1 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 PSMB10 25361965 interaction type N/A PTMCode2
PSMB10 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 PSMC6 25361965 interaction type N/A PTMCode2
PSMC6 PSMD8 25361965 interaction type N/A PTMCode2
PSMD5 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 PSMD5 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
BAG3 PSMD8 25348397 N/A physical interaction ComPPI
PSMC3 PSMD8 25348397 N/A physical interaction ComPPI
PSMC6 PSMD8 25348397 N/A physical interaction ComPPI
PSMD14 PSMD8 19615732 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53BP1 PSMD8 25348397 N/A physical interaction ComPPI
TRAF6 PSMD8 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PSMD7 PSMD8 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPFIA1 PSMD8 25348397 N/A physical interaction ComPPI
PSMB2 PSMD8 25348397 N/A physical interaction ComPPI
JUN PSMD8 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
SMAD2 PSMD8 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
DHX9 PSMD8 25348397 N/A physical interaction ComPPI
PSMA3 PSMD8 25348397 N/A physical interaction ComPPI
PSMD11 PSMD8 25348397 N/A physical interaction ComPPI
DYNC1LI1 PSMD8 25348397 N/A physical interaction ComPPI
TUBG1 PSMD8 25348397 N/A physical interaction ComPPI
UBC PSMD8 25348397 N/A physical interaction ComPPI
NTRK1 PSMD8 25348397 N/A physical interaction ComPPI
SMAD9 PSMD8 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PTPN2 PSMD8 25348397 N/A physical interaction ComPPI
PSMA1 PSMD8 25348397 N/A physical interaction ComPPI
PSMA6 PSMD8 25348397 N/A physical interaction ComPPI
PSMA5 PSMD8 25348397 N/A physical interaction ComPPI
PSMB9 PSMD8 25348397 N/A physical interaction ComPPI
MAP2 PSMD8 25348397 N/A physical interaction ComPPI
SIL1 PSMD8 25348397 N/A physical interaction ComPPI
CFTR PSMD8 25348397 N/A physical interaction ComPPI
PSMD8 UCHL5 11163772 14525934 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
PSMD8 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD8 PAAF1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD8 PSMD13 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD8 RNF185 25348397 N/A physical interaction ComPPI
PSMD8 PSMD4 16990800 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD8 SEM1 25348397 N/A physical interaction ComPPI
PSMD8 PSMC2 25348397 N/A physical interaction ComPPI
PSMD8 RAD23A 25348397 N/A physical interaction ComPPI
PSMD8 PSMD3 25348397 N/A physical interaction ComPPI
PSMD8 PSMC4 25348397 N/A physical interaction ComPPI
PSMD8 PSMC1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD8 PSMC5 25348397 N/A physical interaction ComPPI
PSMD8 PFDN5 25348397 N/A physical interaction ComPPI
PSMD8 PSMA2 25348397 N/A physical interaction ComPPI
PSMD8 CDK2 25348397 N/A physical interaction ComPPI
PSMD8 PSMD12 25348397 N/A physical interaction ComPPI
PSMD8 PSMD1 25348397 N/A physical interaction ComPPI
PSMD8 PSMD2 25348397 N/A physical interaction ComPPI
PSMD8 PSMD10 25348397 N/A physical interaction ComPPI
PSMD8 PSMA7 25348397 N/A physical interaction ComPPI
PSMD8 PSMB7 25348397 N/A physical interaction ComPPI
PSMD8 PSMA4 25348397 N/A physical interaction ComPPI
PSMD8 PSMB5 25348397 N/A physical interaction ComPPI
PSMD8 PSMB6 25348397 N/A physical interaction ComPPI
PSMD8 PSME3 25348397 N/A physical interaction ComPPI
PSMD8 PSMB8 25348397 N/A physical interaction ComPPI
PSMD8 PSMA8 25348397 N/A physical interaction ComPPI
PSMD8 NOS2 25348397 N/A physical interaction ComPPI
PSMD8 PRKN 25348397 N/A physical interaction ComPPI
PSMD8 RNF11 25348397 N/A physical interaction ComPPI
PSMD8 DYNC1I2 25348397 N/A physical interaction ComPPI
PSMD8 ABCF1 25348397 N/A physical interaction ComPPI
PSMD8 HNRNPA0 25348397 N/A physical interaction ComPPI
PSMD8 KCMF1 25348397 N/A physical interaction ComPPI
PSMD8 RPS12 25348397 N/A physical interaction ComPPI
PSMD8 RPS21 25348397 N/A physical interaction ComPPI
PSMD8 TXNL1 25348397 N/A physical interaction ComPPI
PSMD8 RPS8 25348397 N/A physical interaction ComPPI
PSMD8 HUWE1 25348397 N/A physical interaction ComPPI
PSMD8 ABCE1 25348397 N/A physical interaction ComPPI
PSMD8 DVL2 25348397 N/A physical interaction ComPPI
PSMD8 CCDC74B 25348397 N/A physical interaction ComPPI
PSMD8 CCDC92 25348397 N/A physical interaction ComPPI
PSMD8 AMBRA1 25348397 N/A physical interaction ComPPI
PSMD8 HEATR1 25348397 N/A physical interaction ComPPI
PSMD8 ASPM 25348397 N/A physical interaction ComPPI
PSMD8 PSMD5 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD8 PSMD9 25348397 N/A physical interaction ComPPI
PSMD8 PUS1 25348397 N/A physical interaction ComPPI
PSMD8 FOXN2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PSMD8 MAD2L1 25348397 N/A physical interaction ComPPI
PSMD8 ANAPC4 25348397 N/A physical interaction ComPPI
PSMD8 INTU 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PSMD8 BBS5 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PSMD8 MTNR1B 24234451 25348397 26514267 physical association two hybrid,physical interaction ComPPI,IntAct
PSMD8 TRIM25 25348397 N/A physical interaction ComPPI
PSMD8 RNF157 25348397 N/A physical interaction ComPPI
PSMD8 ARF6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD8 MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD8 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
PSMD8 ASXL1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PSMD8 BAP1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PSMD8 SHC3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMD8 PRDX6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMD8 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
SEM1 PSMD8 25348397 N/A physical interaction ComPPI
PSMB4 PSMD8 25348397 N/A physical interaction ComPPI
PSMB1 PSMD8 25348397 N/A physical interaction ComPPI
PSMB3 PSMD8 25348397 N/A physical interaction ComPPI
ADRM1 PSMD8 24234451 24811749 25348397 association physical interaction,blue native page ComPPI,IntAct
UBLCP1 PSMD8 25348397 N/A physical interaction ComPPI
ECPAS PSMD8 25348397 N/A physical interaction ComPPI
MYH10 PSMD8 24234451 30021884 physical association cross-linking study IntAct
L1TD1 PSMD8 24234451 25702638 association anti bait coimmunoprecipitation IntAct

Visualization










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