Gene Information gene info

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GENE：DEDD

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DEDD
FullNmae death effector domain containing
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2755
EnsembleID ENSG00000158796
Uniprot O75618

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DEDD necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DEDD apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DEDD apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
DEDD GO:0003677,GO:0003677,GO:0005515,GO:0005730,GO:0005730,GO:0005737,GO:0007283,GO:0008625,GO:0042177,GO:0042981,GO:0046697,GO:1901837

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CDK1 DEDD 17283331 23180781 physical association anti tag coimmunoprecipitation InnateDB
DEDD DEDD 12527898 17193921 23180781 physical association anti tag coimmunoprecipitation InnateDB
DEDD2 DEDD 12527898 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
FADD DEDD 17193921 23180781 physical association anti tag coimmunoprecipitation InnateDB
CFLAR DEDD 17193921 23180781 physical association anti tag coimmunoprecipitation InnateDB
CASP8 DEDD 23180781 9774341 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
APP DEDD 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 DEDD 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DEDD 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 DEDD 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DEDD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DEDD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DEDD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DEDD 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000033EBB8 DEDD 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 DEDD 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 DEDD 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
GTF3C3 DEDD 25361965 interaction type N/A PTMCode2
DEDD GTF3C3 25361965 interaction type N/A PTMCode2
DEDD KRT18 25361965 interaction type N/A PTMCode2
KRT18 DEDD 25361965 interaction type N/A PTMCode2
CASP10 DEDD 25361965 interaction type N/A PTMCode2
DEDD CASP10 25361965 interaction type N/A PTMCode2
CFLAR DEDD 25361965 interaction type N/A PTMCode2
DEDD CFLAR 25361965 interaction type N/A PTMCode2
CASP3 DEDD 25361965 interaction type N/A PTMCode2
DEDD CASP3 25361965 interaction type N/A PTMCode2
FADD DEDD 25361965 interaction type N/A PTMCode2
DEDD FADD 25361965 interaction type N/A PTMCode2
CASP8 DEDD 25361965 interaction type N/A PTMCode2
DEDD CASP8 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KRT18 DEDD 12235123 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
LTV1 DEDD 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
CASP3 DEDD 12235123 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMAD3 DEDD 20553715 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
USP7 DEDD 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
PAM DEDD 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
ENO1 DEDD 25348397 N/A physical interaction ComPPI
SERPINI1 DEDD 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
CASP8 DEDD 12527898 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
FADD DEDD 14525934 25348397 9774341 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CCNB1 DEDD 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI
CASP10 DEDD 12527898 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ATP6V1E1 DEDD 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
CFLAR DEDD 11741985 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GTF3C3 DEDD 25348397 N/A physical interaction ComPPI
TRIM25 DEDD 25348397 N/A physical interaction ComPPI
DEDD GTF3C1 11965497 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
DEDD DEDD2 11965497 12527898 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DEDD KRT8 12235123 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
DEDD RANBP3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DEDD KHK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DEDD CCDC59 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DEDD USP22 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DEDD HOXD4 25348397 N/A physical interaction ComPPI
DEDD APP 25348397 N/A physical interaction ComPPI
DEDD SHMT1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DEDD BATF2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DEDD APLP2 20195357 24234451 25348397 physical association display technology,physical interaction,tandem affinity purification ComPPI,IntAct
DEDD NXF1 25348397 N/A physical interaction ComPPI
DEDD CDK1 17283331 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DEDD TCEAL5 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
DEDD RSRC2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
DEDD ABCA9 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
DEDD CCZ1B 25348397 N/A display technology ComPPI
DEDD ARID4A 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
DEDD CCZ1 20195357 24234451 physical association display technology IntAct
FADD DEDD 11741985 17193921 27898060 9774341 stimulant N/A OmniPath
DEDD CASP8 11965497 12527898 27898060 9774341 N/A N/A OmniPath
CASP8 DEDD 11965497 12527898 27898060 9774341 stimulant N/A OmniPath

Visualization










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