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GENE：ZFYVE9

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ZFYVE9
FullNmae zinc finger FYVE-type containing 9
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6775
EnsembleID ENSG00000157077
Uniprot O95405

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ZFYVE9 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ZFYVE9 GO:0005515,GO:0005545,GO:0005769,GO:0005829,GO:0006897,GO:0007179,GO:0007179,GO:0007179,GO:0016197,GO:0019904,GO:0031901,GO:0031901,GO:0031901,GO:0032991,GO:0043231,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ZFYVE9 hsa:9372 path:hsa04144 Endocytosis - Homo sapiens (human)
ZFYVE9 hsa:9372 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ZFYVE9 SMAD2 11243848 15231748 15356634 18511908 18988627 19620243 21071413 23331499 26192618 9865696 interaction type,stimulation N/A ACSN,SignaLink,SignaLink
SMAD4 ZFYVE9 15613484 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD2 ZFYVE9 15613484 17272273 18729074 23180781 physical association anti tag coimmunoprecipitation,tandem affinity purification InnateDB
ZFYVE9 ZFYVE9 20515759 26467481 9865696 bind,up-regulates activity,relocalization reaction N/A Signor
ZFYVE9 TGFBR1 12052882 18988627 23331499 9865696 stimulation N/A SignaLink,SignaLink
PML ZFYVE9 15356634 18988627 21071413 23331499 stimulation N/A SignaLink,SignaLink
HGS ZFYVE9 11094085 23331499 stimulation N/A SignaLink
NUP214 ZFYVE9 12191473 23331499 inhibition N/A SignaLink
NUP153 ZFYVE9 12191473 23331499 inhibition N/A SignaLink

Source Target Pmid Interactiontype Methods Database
PPP2R1A ZFYVE9 20005715 interaction type N/A PSP
PPP2R1A ZFYVE9 15231748 18988627 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR ZFYVE9 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ZFYVE9 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ZFYVE9 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ZFYVE9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ZFYVE9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ZFYVE9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ZFYVE9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ZFYVE9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ZFYVE9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 ZFYVE9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ZFYVE9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ZFYVE9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ZFYVE9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ZFYVE9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ZFYVE9 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 ZFYVE9 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 ZFYVE9 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA ZFYVE9 23592263 25416803 26701625 27292025 27508097 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS000006FDD4 ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000042E1F ZFYVE9 23592263 25416803 26701625 26729221 27292025 27508097 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS00000DDD35 ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000039E1E1 ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000315338 ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000600E6 ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001C11BC ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002C0FCB ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002B3783 ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000037D7E5 ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00003883FE ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000298BA3 ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000031602A ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000251D0B ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000003E1A9 ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00004F4657 ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000F6E49 ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000025EABA ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000006F90B ZFYVE9 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075B538 ZFYVE9 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E ZFYVE9 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 ZFYVE9 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A ZFYVE9 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 ZFYVE9 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LRP12 ZFYVE9 25361965 interaction type N/A PTMCode2
ZFYVE9 LRP12 25361965 interaction type N/A PTMCode2
ZFYVE9 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 ZFYVE9 25361965 interaction type N/A PTMCode2
PML ZFYVE9 25361965 interaction type N/A PTMCode2
ZFYVE9 PML 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PPP1CC ZFYVE9 14525934 15231748 24234451 24366813 25348397 25416956 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 NUP155 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 SUMF2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 ETS2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 UBXN11 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 RNPEP 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 FHL2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 EIF4G1 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ZFYVE9 ZMYND8 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 CHD6 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 RBBP6 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 RHOT2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 SPART 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 BMP4 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 SCYL2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 JUP 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 NIT1 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 PPP1CA 14525934 15231748 22321011 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 BAG6 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 TGFBR2 14525934 25348397 9865696 N/A experimental interaction detection,in vivo ComPPI,HPRD
ZFYVE9 SMAD2 14525934 15231748 18511908 24234451 25348397 9865696 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 SMAD3 12154125 14525934 15231748 24234451 25348397 9865696 physical association two hybrid,experimental interaction detection,x-ray crystallography,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 LRP12 12809483 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 PML 14525934 15356634 18511908 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
ZFYVE9 RNF11 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 SUPT5H 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 CTNNB1 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 TENT5A 14525934 15231748 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
ZFYVE9 PPP1CB 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 DAZAP2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 ERBIN 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ZFYVE9 SVEP1 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 STAM2 25348397 N/A physical interaction ComPPI
ZFYVE9 TSG101 25348397 N/A physical interaction ComPPI
ZFYVE9 UBC 25348397 N/A physical interaction ComPPI
ZFYVE9 PPP2R1A 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ZFYVE9 ANKLE2 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ZFYVE9 PPARG 25348397 N/A physical interaction ComPPI
ZFYVE9 CLTC 25348397 N/A physical interaction ComPPI
ZFYVE9 PPP1R3A 25348397 N/A physical interaction ComPPI
ZFYVE9 HERC2 25348397 N/A physical interaction ComPPI
ZFYVE9 HERC2P3 25348397 N/A physical interaction ComPPI
ZFYVE9 NCKIPSD 25348397 N/A physical interaction ComPPI
ZFYVE9 DEFA6 25348397 N/A physical interaction ComPPI
ZFYVE9 ST7 25348397 N/A physical interaction ComPPI
ZFYVE9 RHO 17693260 24234451 25348397 physical association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
ZFYVE9 STX3 17693260 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,pull down,confocal microscopy ComPPI,IntAct
ZFYVE9 EEA1 17693260 24234451 25348397 29568061 colocalization,association confocal microscopy,proximity-dependent biotin identification ComPPI,IntAct
ZFYVE9 FOS 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
ZFYVE9 RAB9A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ZFYVE9 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ZFYVE9 TGFBR1 14525934 9865696 N/A experimental interaction detection HPRD
TGFBR2 ZFYVE9 27898060 9865696 stimulant N/A OmniPath
PML ZFYVE9 15356634 16916642 18511908 27898060 stimulant N/A OmniPath
ZFYVE9 SMAD2 11094085 11243848 15231748 15356634 15613484 16916642 17272273 18511908 18729074 20515759 23687300 27898060 9865696 stimulant N/A OmniPath
ZFYVE9 TGFBR1 12052882 27898060 9865696 inhibition,stimulant N/A OmniPath
TGFBR1 ZFYVE9 27898060 9865696 stimulant N/A OmniPath
ZFYVE9 SMAD3 12154125 15231748 15356634 18729074 20515759 26186194 27898060 9865696 stimulant N/A OmniPath
NUP214 ZFYVE9 12191473 27898060 inhibition N/A OmniPath
HGS ZFYVE9 11094085 27898060 stimulant N/A OmniPath
NUP153 ZFYVE9 12191473 27898060 inhibition N/A OmniPath

Visualization










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