Gene Information gene info

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GENE：INHBA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol INHBA
FullNmae inhibin subunit beta A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6066
EnsembleID ENSG00000122641
Uniprot P08476

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
INHBA mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
INHBA immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
INHBA autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
INHBA apoptosis 35596068 Furthermore, miR-211 upregulation or INHBA silencing decreased tumor growth and cell apoptosis in vivo. retulator signature
INHBA apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
INHBA GO:0001541,GO:0001541,GO:0001934,GO:0001942,GO:0002244,GO:0005125,GO:0005125,GO:0005179,GO:0005515,GO:0005576,GO:0005576,GO:0005615,GO:0006357,GO:0006366,GO:0006952,GO:0007166,GO:0007267,GO:0007399,GO:0008083,GO:0008285,GO:0008584,GO:0010628,GO:0017046,GO:0019221,GO:0021773,GO:0030154,GO:0030218,GO:0030308,GO:0032689,GO:0032924,GO:0032967,GO:0035987,GO:0042326,GO:0042476,GO:0042541,GO:0042701,GO:0042802,GO:0043509,GO:0043512,GO:0044877,GO:0045578,GO:0045648,GO:0045650,GO:0045893,GO:0045944,GO:0045945,GO:0046880,GO:0046881,GO:0046882,GO:0048333,GO:0048471,GO:0051247,GO:0060021,GO:0060279,GO:0060391,GO:0060936,GO:0061029,GO:0070374,GO:0070699,GO:0071372,GO:0071397,GO:0097154,GO:0097191,GO:1904044,GO:1904385,GO:2000134,GO:2001241

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
INHBA hsa:3624 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
INHBA hsa:3624 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)
INHBA hsa:3624 path:hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
INHBA INHBA 23180781 9843440 physical association cross-linking study InnateDB
INHBA ACVR2B 16446785 23331499 stimulation N/A SignaLink,SignaLink
INHBA ACTR2 16446785 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ESR1 INHBA 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 INHBA 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 INHBA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA INHBA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF INHBA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 INHBA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 INHBA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 INHBA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 INHBA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A INHBA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A INHBA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF INHBA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 INHBA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 INHBA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 INHBA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ATF1 INHBA N/A trascriptional regulation,stimulation inferred by curator TFlink
CREB1 INHBA N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000521626 INHBA 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS0000001EB3 INHBA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004AC389 INHBA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000029D793 INHBA 20371350 21572407 22012620 23446348 23592263 24398324 25416803 26701625 27292025 28735896 mrna cleavage,inhibition clip TarBase
URS000005A8ED INHBA 20371350 21572407 22012620 23446348 23592263 24398324 25416803 26701625 27292025 28735896 mrna cleavage,inhibition clip TarBase
URS000052EA98 INHBA 20371350 21572407 22012620 23446348 23592263 24398324 25416803 26701625 27292025 28735896 mrna cleavage,inhibition clip TarBase
URS000012930C INHBA 20371350 21572407 22012620 23446348 23592263 24398324 25416803 26701625 27292025 28735896 mrna cleavage,inhibition clip TarBase
URS000015188E INHBA 20371350 21572407 22012620 23446348 23592263 24398324 25416803 26701625 27292025 28735896 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 INHBA 20371350 21572407 22012620 23446348 23592263 24398324 25416803 26701625 27292025 28735896 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 INHBA 20371350 21572407 22012620 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000080D0A INHBA 20371350 21572407 22012620 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000008AA34 INHBA 20371350 21572407 22012620 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002C02E4 INHBA 20371350 21572407 22012620 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000039A25B INHBA 20371350 21572407 22012620 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075B13F INHBA 20371350 21572407 22012620 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075AEA5 INHBA 20371350 21572407 22012620 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00004283FE INHBA 20371350 21572407 22012620 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000118224 INHBA 20371350 21572407 22012620 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000037B2E0 INHBA 20371350 21572407 22012620 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000319E1 INHBA 20371350 21572407 22012620 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000496C56 INHBA 20371350 21572407 22012620 23446348 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000160683 INHBA 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000B7E30 INHBA 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001CF056 INHBA 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075B538 INHBA 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000027464B INHBA 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
IGFBP7 INHBA 10859029 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
ACVR1B INHBA 14525934 25348397 8397373 N/A coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TGFBR3 INHBA 10746731 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ACVRL1 INHBA 25348397 N/A physical interaction ComPPI
IGSF1 INHBA 25348397 N/A physical interaction ComPPI
ACVR2B INHBA 14525934 25348397 9202237 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ACVR1 INHBA 11266516 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ENG INHBA 14525934 25348397 9872992 N/A experimental interaction detection,in vitro ComPPI,HPRD
INHBA ACVR2A 11266516 14525934 25348397 N/A coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
INHBA FST 14525934 25348397 7887917 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
INHBA INHBB 11134153 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
INHBA INHBC 11134153 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
INHBA FSTL3 11459787 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
INHBA CHRDL2 14525934 15094188 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
INHA INHBA 11134153 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
INHBA INHBA 11134153 14525934 N/A experimental interaction detection HPRD
FST INHBA 22037168 27898060 7887917 inhibition N/A OmniPath
INHBA BAMBI 10918299 27898060 stimulant N/A OmniPath
INHBA ACVR2B 20860622 27898060 8242742 8622651 9202237 stimulant N/A OmniPath
INHBA ACVR1B 27898060 7890768 8167568 8397373 9605406 stimulant N/A OmniPath
INHBA ACVR2A 10746731 11266516 12466190 1646080 27898060 8242742 9202237 9605406 stimulant N/A OmniPath

Visualization










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