Gene Information gene info

GENE:ID3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ID3
FullNmae inhibitor of DNA binding 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5362
EnsembleID ENSG00000117318
Uniprot Q02535

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ID3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ID3 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ID3 GO:0000122,GO:0000122,GO:0001656,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0006275,GO:0007417,GO:0007507,GO:0007517,GO:0010628,GO:0010629,GO:0019904,GO:0030154,GO:0030182,GO:0030855,GO:0030903,GO:0032922,GO:0042476,GO:0043065,GO:0043425,GO:0043433,GO:0045662,GO:0045668,GO:0045892,GO:0046983,GO:0072750,GO:0140110,GO:0140416,GO:1901707

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ID3 hsa:3399 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)
ID3 hsa:3399 path:hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TSC1 ID3 17355907 23180781 physical association two hybrid InnateDB
ELAVL1 ID3 19289500 23180781 physical association anti tag coimmunoprecipitation InnateDB
LYL1 ID3 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR ID3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 ID3 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 ID3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ID3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 ID3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC ID3 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 ID3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 ID3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ID3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ID3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ID3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ID3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ID3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ID3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ID3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ID3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PTTG1 ID3 16926250 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ID3 N/A trascriptional regulation,stimulation inferred by curator TFlink
SMAD1 ID3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000075D15B ID3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC ID3 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000355E82 ID3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 ID3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075B0F6 ID3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 ID3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 ID3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000076995 ID3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000272A3D ID3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000030F801 ID3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 ID3 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 ID3 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
TCF4 ID3 25361965 interaction type N/A PTMCode2
ID3 TCF4 25361965 interaction type N/A PTMCode2
MKI67 ID3 25361965 interaction type N/A PTMCode2
ID3 MKI67 25361965 interaction type N/A PTMCode2
HES1 ID3 25361965 interaction type N/A PTMCode2
ID3 HES1 25361965 interaction type N/A PTMCode2
TCF3 ID3 25361965 interaction type N/A PTMCode2
ID3 TCF3 25361965 interaction type N/A PTMCode2
MYOD1 ID3 25361965 interaction type N/A PTMCode2
ID3 MYOD1 25361965 interaction type N/A PTMCode2
ID3 CDK2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LMO4 ID3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZNF408 ID3 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FRS3 ID3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HOXA1 ID3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MYOG ID3 14525934 25348397 9242638 N/A two hybrid,two hybrid ComPPI,HPRD
ID3 SREBF1 10585876 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ID3 STON1 25348397 N/A two hybrid,in vivo ComPPI
ID3 ID4 14525934 25348397 8759016 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
ID3 CDK2 14525934 25348397 9372912 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ID3 MYF6 14525934 25348397 9242638 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
ID3 ADD1 10585876 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ID3 HES1 11756408 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
ID3 IFI16 11940648 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ID3 ELK1 10022839 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ID3 ELK4 10022839 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ID3 TCF12 14525934 24234451 25348397 25416956 9242638 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
ID3 RUNX1T1 11591653 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ID3 TCF3 14525934 24234451 25348397 25416956 8759016 9525934 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
ID3 MYOD1 14525934 25348397 8759016 9242638 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
ID3 MYF5 14525934 24234451 25348397 9242638 physical association two hybrid,experimental interaction detection,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
ID3 TCF4 11591653 14525934 24234451 25348397 25416956 25609649 8999959 association,physical association experimental interaction detection,physical interaction,two hybrid array,tandem affinity purification,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
ID3 PAX5 12054881 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
ID3 GATA4 25348397 N/A physical interaction ComPPI
ID3 NKX2-5 25348397 N/A physical interaction ComPPI
ID3 E2F4 25348397 N/A physical interaction ComPPI
ID3 IKBKG 25348397 N/A physical interaction ComPPI
ID3 SAP30 25348397 N/A physical interaction ComPPI
ID3 CBFA2T2 25348397 N/A physical interaction ComPPI
ID3 PRDM14 25348397 N/A physical interaction ComPPI
ID3 SMURF2 25348397 N/A physical interaction ComPPI
ID3 ATF3 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ID3 CNOT3 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ID3 CSK 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ID3 FHL2 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ID3 GNB2 25348397 N/A physical interaction ComPPI
ID3 RND1 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ID3 PUF60 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ID3 MLX 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ID3 ZNF3 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ID3 ZNF626 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ID3 UNK 25348397 N/A physical interaction ComPPI
ID3 ELOC 25348397 N/A physical interaction ComPPI
ID3 VHL 25348397 N/A physical interaction ComPPI
ID3 PDLIM5 16549780 24234451 25348397 N/A pull down,physical interaction ComPPI,IntAct
ID3 TSC1 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
ID3 FAM74A1 24234451 25348397 25416956 physical association two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ID3 KRTAP26-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ID3 C22ORF39 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ID3 SDCBP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ID3 KAT5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ID3 MSGN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ID3 ID3 14525934 18255255 24234451 8645731 physical association two hybrid,experimental interaction detection HPRD,IntAct
GTF2A1L ID3 14525934 8759016 N/A experimental interaction detection,two hybrid HPRD
ID3 COPS5 15451666 27898060 N/A N/A OmniPath
ID3 TCF3 11175815 12614353 15016815 22354994 25416956 27898060 8759016 9242638 9525934 inhibition N/A OmniPath
EGR1 ID3 12165491 27898060 stimulant N/A OmniPath
CDK2 ID3 25090023 27898060 9372912 inhibition N/A OmniPath
ID3 ATOH1 16407553 27898060 inhibition N/A OmniPath
ID3 TSC1 17355907 27898060 N/A N/A OmniPath
TSC1 ID3 17355907 27898060 N/A N/A OmniPath

Visualization