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GENE：TGFBR2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TGFBR2
FullNmae transforming growth factor beta receptor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11773
EnsembleID ENSG00000163513
Uniprot P37173

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TGFBR2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TGFBR2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TGFBR2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TGFBR2 GO:0001568,GO:0001569,GO:0001570,GO:0001701,GO:0001947,GO:0002053,GO:0002088,GO:0002651,GO:0002663,GO:0002666,GO:0003148,GO:0003149,GO:0003151,GO:0003180,GO:0003181,GO:0003186,GO:0003214,GO:0003274,GO:0003430,GO:0004675,GO:0005024,GO:0005024,GO:0005024,GO:0005024,GO:0005026,GO:0005515,GO:0005524,GO:0005539,GO:0005576,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0005886,GO:0005901,GO:0006468,GO:0006468,GO:0006915,GO:0007179,GO:0007179,GO:0007179,GO:0007179,GO:0007179,GO:0007219,GO:0007224,GO:0007369,GO:0007420,GO:0007507,GO:0007507,GO:0008284,GO:0009410,GO:0009897,GO:0010468,GO:0010634,GO:0010718,GO:0016020,GO:0017002,GO:0018105,GO:0018107,GO:0019209,GO:0032147,GO:0032924,GO:0034713,GO:0034713,GO:0035162,GO:0035909,GO:0042127,GO:0043011,GO:0043235,GO:0043235,GO:0045121,GO:0045766,GO:0046332,GO:0046332,GO:0046872,GO:0048185,GO:0048701,GO:0048844,GO:0050431,GO:0050431,GO:0050431,GO:0051138,GO:0060021,GO:0060090,GO:0060391,GO:0060395,GO:0060412,GO:0060434,GO:0060440,GO:0060443,GO:0060463,GO:0061520,GO:0062009,GO:0070021,GO:0070021,GO:0070723,GO:0071363,GO:0072091,GO:1905007,GO:1905317,GO:1990086,GO:1990428,GO:2000379,GO:2000563

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TGFBR2 hsa:7048 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa04068 FoxO signaling pathway - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa04144 Endocytosis - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa04218 Cellular senescence - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa04390 Hippo signaling pathway - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa04520 Adherens junction - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa04926 Relaxin signaling pathway - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa05142 Chagas disease - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa05161 Hepatitis B - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa05200 Pathways in cancer - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa05210 Colorectal cancer - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa05212 Pancreatic cancer - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa05220 Chronic myeloid leukemia - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa05226 Gastric cancer - Homo sapiens (human)
TGFBR2 hsa:7048 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TGFBR2 TGFBR1 10678166 11013220 11102446 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16446785 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 18988627 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21071413 21098712 21278795 21372296 21614932 21791611 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23331499 23784029 24132110 24336330 24403530 26192618 26201938 26966341 2871107 7594497 7890683 8515656 8576253 9311995 9865696 interaction type,stimulation N/A ACSN,SignaLink,SignaLink
TGFB1 TGFBR2 10678166 11013220 11133108 11157754 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16446785 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21071413 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23331499 23784029 24132110 24336330 24403530 26192618 26201938 26966341 2871107 7594497 8515656 9311995 9865696 interaction type,stimulation N/A ACSN,SignaLink,SignaLink
TGFBR2 PARD6A 11133108 14557817 15265520 15548370 15761148 15761153 16474430 17934056 19010789 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22315516 22703233 22949611 24132110 24336330 26192618 7594497 interaction type N/A ACSN
FKBP1A TGFBR2 11226255 14766396 26192618 interaction type N/A ACSN
IL6 TGFBR2 11306493 15099563 15356132 15573129 18209571 18555777 18555778 19581928 20138012 23034983 23567181 24011634 24346288 25002027 25582338 26192618 26201938 26268945 27557510 7590867 8837607 9845545 interaction type N/A ACSN
CAV1 TGFBR2 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26192618 26828520 interaction type N/A ACSN
TGFBR2 SMAD3 11274345 14557817 15265520 16474430 17934056 20060931 20519943 21614932 22703233 24132110 24336330 26192618 interaction type N/A ACSN
TGFBR2 SMAD2 11274345 14557817 15265520 16474430 17934056 20060931 20519943 21614932 22703233 24132110 24336330 26192618 interaction type N/A ACSN
ILK TGFBR2 11696562 15905178 24527345 25100717 25268583 26192618 27111285 interaction type N/A ACSN
TGFBR2 EGF 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16424049 16474430 16572188 17070508 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26192618 26201938 26966341 2871107 7594497 8515656 interaction type N/A ACSN
TGFBR2 TRAF6 11013220 11133108 12154066 12717440 12724770 12767520 12809600 14557817 15265520 15548370 16474430 17673906 17934056 18758450 18922473 19010789 19050695 19109155 19114990 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 22943793 23331499 24132110 24336330 26192618 7594497 9865696 interaction type,stimulation N/A ACSN,SignaLink
IL15 TGFBR2 10426994 10952726 11907067 14607946 15536084 16713974 17398124 17459805 19913445 20007590 21307131 25582338 26192618 7523571 interaction type N/A ACSN
IL18 TGFBR2 10679398 11592085 14504095 14662834 15099563 15802534 26192618 26885855 27048821 27066895 9469432 interaction type N/A ACSN
TGFBR2 CCL2 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16127449 16424049 16474430 16572188 17070508 17404308 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19732719 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26192618 26201938 26966341 2871107 7594497 8515656 interaction type N/A ACSN
TGFBR2 CCL5 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16127449 16424049 16474430 16572188 17070508 17404308 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19732719 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26192618 26201938 26966341 2871107 7594497 8515656 interaction type N/A ACSN
TGFBR2 MAP2K4 11274345 12738796 14557817 15265520 15282297 16200688 16474430 17934056 18855897 20060931 20519943 21614932 22703233 23070005 24132110 24336330 24403530 26192618 interaction type N/A ACSN
TGFBR2 MAP2K6 11274345 12738796 14557817 15265520 15282297 16200688 16474430 17934056 18855897 20060931 20519943 21614932 22703233 23070005 24132110 24336330 24403530 26192618 interaction type N/A ACSN
TGFBR2 SMAD4 11274345 14557817 15265520 16474430 17934056 20060931 20519943 21614932 22703233 24132110 24336330 26192618 interaction type N/A ACSN
TGFBR2 TGFBR2 12015308 23180781 26467481 7774578 8576253 9155023 9169454 9865696 phosphorylation reaction,bind,up-regulates activity,down-regulates activity in-gel kinase assay InnateDB,Signor
TGFBR2 ACVRL1 18333754 23180781 physical association anti tag coimmunoprecipitation InnateDB
TGFB3 TGFBR2 11157754 11382746 11850637 12729750 15017149 16446785 18243111 18988627 21071413 23180781 23331499 8106553 9872992 stimulation,physical association nuclear magnetic resonance,surface plasmon resonance,x-ray crystallography InnateDB,SignaLink,SignaLink
TGFBR1 TGFBR2 18243111 23180781 physical association surface plasmon resonance InnateDB
TGFBR2 NFYA 11744689 23180781 physical association affinity chromatography technology,electrophoretic mobility shift assay InnateDB
TGFBR2 NFYB 11744689 23180781 physical association electrophoretic mobility shift assay InnateDB
KAT2B TGFBR2 11744689 23180781 physical association affinity chromatography technology InnateDB
TGFBR2 JUN 11741970 23180781 physical association electrophoretic mobility shift assay InnateDB
TGFBR2 SP1 10982796 11741970 23180781 physical association electrophoretic mobility supershift assay,electrophoretic mobility shift assay InnateDB
TGFBR2 GRB2 18174260 23180781 physical association anti tag coimmunoprecipitation InnateDB
TGFBR2 ELF3 23180781 9417054 physical association electrophoretic mobility shift assay InnateDB
TGFBR2 ENG 12015308 16785228 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD2 TGFBR2 23180781 8980228 physical association anti tag coimmunoprecipitation InnateDB
ACVRL1 TGFBR2 18333754 23180781 physical association cross-linking study InnateDB
TGFBR2 SPARC 15034927 23180781 physical association anti tag coimmunoprecipitation InnateDB
TGFBR2 EGR1 10982796 23180781 physical association electrophoretic mobility supershift assay InnateDB
TGFBR2 SP3 10982796 23180781 physical association electrophoretic mobility supershift assay InnateDB
TGFBR2 CEBPD 21072181 23180781 physical association anti tag coimmunoprecipitation InnateDB
TGFBR2 POLR2F 23180781 23994473 physical association anti tag coimmunoprecipitation InnateDB
APP TGFBR2 21832049 23180781 physical association protein array InnateDB
TGFB2 TGFBR2 11157754 16446785 21071413 23331499 stimulation N/A SignaLink,SignaLink
SRC TGFBR2 19114990 23331499 stimulation N/A SignaLink,SignaLink
DAB2 TGFBR2 11387212 23331499 stimulation N/A SignaLink
DAXX TGFBR2 11483955 23331499 stimulation N/A SignaLink
TGFBR2 MAP3K7 16360132 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
PIK3R1 TGFBR2 20005715 interaction type N/A PSP
SNX6 TGFBR2 20005715 interaction type N/A PSP
TGFBRAP1 TGFBR2 20005715 interaction type N/A PSP
PIK3R1 TGFBR2 18988627 20005715 21071413 9435577 N/A N/A SignaLink
SNX6 TGFBR2 11279102 18988627 20005715 N/A N/A SignaLink
TGFBRAP1 TGFBR2 11278302 18988627 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR TGFBR2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 TGFBR2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TGFBR2 10508522 14976186 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 TGFBR2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TGFBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TGFBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TGFBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TGFBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 TGFBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 TGFBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TGFBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 TGFBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 TGFBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 TGFBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 TGFBR2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TGFBR2 10982796 trascriptional regulation,stimulation inferred by curator TFlink
ETV4 TGFBR2 14976186 trascriptional regulation,stimulation inferred by curator TFlink
EWSR1 TGFBR2 10508522 trascriptional regulation,stimulation inferred by curator TFlink
FLI1 TGFBR2 10508522 trascriptional regulation,stimulation inferred by curator TFlink
HDAC2 TGFBR2 19088080 trascriptional regulation,stimulation inferred by curator TFlink
SP6 TGFBR2 19088080 trascriptional regulation,stimulation inferred by curator TFlink
SP1 TGFBR2 10982796 11687969 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 TGFBR2 10982796 11687969 trascriptional regulation,stimulation inferred by curator TFlink
ERG TGFBR2 N/A trascriptional regulation,stimulation inferred by curator TFlink
ETS2 TGFBR2 N/A trascriptional regulation,stimulation inferred by curator TFlink
SP3 TGFBR2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002075FA TGFBR2 20940405 rna interference,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000035CC3E TGFBR2 20940405 rna interference,inhibition array technology,miRNA interference luciferase reporter assay miRSponge
URS000006FDD4 TGFBR2 20940405 rna interference,inhibition array technology,miRNA interference luciferase reporter assay miRSponge
URS000029D9F1 TGFBR2 20056717 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000042E1F TGFBR2 N/A 16461460 20940405 rna interference,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000009262D TGFBR2 18829576 19816956 19906824 22072622 rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000346991 TGFBR2 21490602 rna interference,inhibition array technology,western blot,quantitative reverse transcription pcr,immunocytochemistry,miRNA interference luciferase reporter assay miRSponge
URS0000272039 TGFBR2 19398468 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000009262D TGFBR2 18591254 18829576 19816956 19906824 22072622 24037531 25416803 27388239 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000042E1F TGFBR2 16461460 19435428 20371350 20940405 21572407 22012620 22473208 25416803 26729221 27080303 27508097 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS000029D9F1 TGFBR2 20056717 21282569 25416803 mrna cleavage,inhibition array technology,miRNA interference luciferase reporter assay TarBase
URS00002075FA TGFBR2 20371350 20940405 21572407 22012620 22473208 25011053 25416803 27120811 27508097 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS000035CC3E TGFBR2 20940405 25416803 28131417 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000006FDD4 TGFBR2 20371350 20940405 21572407 22012620 22473208 24220575 25416803 25443138 27080303 27098600 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000272039 TGFBR2 19398468 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000346991 TGFBR2 21490602 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,immunocytochemistry,miRNA interference luciferase reporter assay TarBase
URS000039E1E1 TGFBR2 20371350 21572407 22012620 22912877 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00004900F1 TGFBR2 21666718 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 TGFBR2 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00002C0FCB TGFBR2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00000DDD35 TGFBR2 20371350 21572407 22012620 22473208 24606633 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,nucleotide sequence identification,western blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS000027352D TGFBR2 22012620 22336710 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000508C13 TGFBR2 22020335 25416803 25980442 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00004F4657 TGFBR2 22942087 23986572 25323858 25416803 27388239 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000044FD7 TGFBR2 24039954 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00005E1A16 TGFBR2 23690952 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000315338 TGFBR2 20371350 21572407 22012620 25416803 27304191 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS00001E0AEA TGFBR2 20371350 21572407 22012620 25416803 26572508 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00000600E6 TGFBR2 20371350 21572407 22012620 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC TGFBR2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 TGFBR2 20371350 21572407 22012620 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 TGFBR2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE TGFBR2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 TGFBR2 20371350 21572407 22012620 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 TGFBR2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A TGFBR2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B TGFBR2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000042619A TGFBR2 22012620 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 TGFBR2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008C563 TGFBR2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 TGFBR2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 TGFBR2 22012620 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000081E1F TGFBR2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C TGFBR2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000EED18 TGFBR2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002C7B2B TGFBR2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001F5B39 TGFBR2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003758F0 TGFBR2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002198F3 TGFBR2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 TGFBR2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 TGFBR2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000B0E50 TGFBR2 22012620 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA TGFBR2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B TGFBR2 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002C28B2 TGFBR2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000016E46F TGFBR2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001C04A2 TGFBR2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000030F801 TGFBR2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001CF056 TGFBR2 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001A122A TGFBR2 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 TGFBR2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000358C16 TGFBR2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000017EA6A TGFBR2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 TGFBR2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000029D793 TGFBR2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001938D9 TGFBR2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000250A40 TGFBR2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED TGFBR2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000052E1A6 TGFBR2 25416803 26940097 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00003D8730 TGFBR2 25416803 28373289 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS000018C928 TGFBR2 25416803 26682928 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS0000183BED TGFBR2 25416803 27388239 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000041E949 TGFBR2 25416803 28352351 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
SRC TGFBR2 22135298 phosphorylation N/A PhosphoSite
TGFBR2 TGFBR1 22135298 phosphorylation N/A PhosphoSite
TGFBR2 TGFBR2 22135298 phosphorylation N/A PhosphoSite
TGFBR2 ENG 22135298 phosphorylation N/A PhosphoSite
ZFYVE9 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 ZFYVE9 25361965 interaction type N/A PTMCode2
CCNB2 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 CCNB2 25361965 interaction type N/A PTMCode2
TRAP1 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 TRAP1 25361965 interaction type N/A PTMCode2
SMAD4 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 SMAD4 25361965 interaction type N/A PTMCode2
SMAD7 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 SMAD7 25361965 interaction type N/A PTMCode2
TGFB3 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 TGFB3 25361965 interaction type N/A PTMCode2
SMURF2 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 SMURF2 25361965 interaction type N/A PTMCode2
DYNLT4 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 DYNLT4 25361965 interaction type N/A PTMCode2
TGFB1 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 TGFB1 25361965 interaction type N/A PTMCode2
DAB2 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 DAB2 25361965 interaction type N/A PTMCode2
TGFBR3 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 TGFBR3 25361965 interaction type N/A PTMCode2
PML TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 PML 25361965 interaction type N/A PTMCode2
TGFBR2 SNX6 25361965 interaction type N/A PTMCode2
SNX6 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 EIF3I 25361965 interaction type N/A PTMCode2
EIF3I TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 TGFB1I1 25361965 interaction type N/A PTMCode2
TGFB1I1 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 STRAP 25361965 interaction type N/A PTMCode2
STRAP TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 TGFBR2 25361965 interaction type N/A PTMCode2
ACVRL1 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 ACVRL1 25361965 interaction type N/A PTMCode2
CTNNB1 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 CTNNB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIK3R2 TGFBR2 14525934 25348397 9435577 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
DAXX TGFBR2 11483955 24234451 25348397 physical association two hybrid,coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
CDC42 TGFBR2 25348397 N/A physical interaction ComPPI
SH3KBP1 TGFBR2 25348397 N/A physical interaction ComPPI
ZFYVE9 TGFBR2 14525934 25348397 9865696 N/A experimental interaction detection,in vivo ComPPI,HPRD
OXSR1 TGFBR2 25348397 N/A physical interaction ComPPI
TGFB1 TGFBR2 14525934 20856203 20860622 21054789 21441952 24234451 25348397 7935686 association,physical association anti tag coimmunoprecipitation,coimmunoprecipitation,cross-linking study,experimental interaction detection,surface plasmon resonance,physical interaction,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
TRAF6 TGFBR2 25348397 N/A physical interaction ComPPI
TYK2 TGFBR2 25348397 N/A physical interaction ComPPI
SMAD4 TGFBR2 14525934 25348397 8774881 N/A experimental interaction detection,in vitro ComPPI,HPRD
FBXO34 TGFBR2 25348397 N/A physical interaction ComPPI
CD44 TGFBR2 12145287 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ERBB2 TGFBR2 25348397 N/A physical interaction ComPPI
PAK1 TGFBR2 25348397 N/A physical interaction,in vivo ComPPI
SMURF2 TGFBR2 25348397 N/A physical interaction ComPPI
DAB2 TGFBR2 11387212 14525934 24234451 25348397 association cross-linking study,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CBL TGFBR2 25348397 N/A physical interaction ComPPI
TGFBR2 CLU 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
TGFBR2 TGFB2 25348397 N/A physical interaction,in vitro,in vivo ComPPI
TGFBR2 TGFB3 11382746 11850637 12729750 14525934 21423151 24234451 25348397 8106553 physical association experimental interaction detection,molecular sieving,surface plasmon resonance,x-ray crystallography,physical interaction,ion exchange chromatography,blue native page,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
TGFBR2 TGFBR3 11323414 14525934 25348397 N/A cross-linking study,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TGFBR2 ACVRL1 10716993 14525934 25348397 N/A anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TGFBR2 TGFB1I1 12421567 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TGFBR2 CCNB2 14525934 25348397 9926943 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
TGFBR2 SMAD7 11163210 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TGFBR2 EIF3I 11781097 14525934 25348397 7566156 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TGFBR2 STRAP 14525934 25348397 9856985 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
TGFBR2 TGFBRAP1 11278302 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TGFBR2 SNX6 11279102 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TGFBR2 PML 14525934 15356634 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TGFBR2 SMAD3 14525934 25348397 8774881 N/A experimental interaction detection,in vitro ComPPI,HPRD
TGFBR2 CTNNB1 12000714 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TGFBR2 PIK3R1 14525934 25348397 9435577 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TGFBR2 AP2B1 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
TGFBR2 TRAP1 11278302 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
TGFBR2 ARHGEF6 14525934 15761153 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TGFBR2 ARHGEF7 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TGFBR2 KCNK18 14525934 15761153 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TGFBR2 CCNB1 14525934 25348397 9926943 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TGFBR2 DYNLT4 14525934 16982625 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
TGFBR2 ENG 14525934 25348397 9872992 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TGFBR2 SPARC 25348397 N/A anti tag coimmunoprecipitation ComPPI
TGFBR2 TGFBR1 14525934 25348397 7890683 8576253 N/A anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
TGFBR2 ACVR1 25348397 N/A physical interaction ComPPI
TGFBR2 HSP90AA1 25348397 N/A physical interaction ComPPI
TGFBR2 HSP90AA2P 25348397 N/A physical interaction ComPPI
TGFBR2 SMURF1 25348397 N/A physical interaction ComPPI
TGFBR2 TSC22D1 25348397 N/A physical interaction ComPPI
TGFBR2 MAP3K7 25348397 N/A physical interaction ComPPI
TGFBR2 PPP1R16B 25348397 N/A physical interaction ComPPI
TGFBR2 OCLN 25348397 N/A physical interaction ComPPI
TGFBR2 APP 25348397 N/A physical interaction ComPPI
TGFBR2 PEG10 25348397 N/A physical interaction ComPPI
TGFBR2 NRP1 25348397 N/A physical interaction ComPPI
TGFBR2 TERT 25348397 N/A physical interaction ComPPI
TGFBR2 PDGFRA 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFBR2 RCVRN 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFBR2 GOPC 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFBR2 NRP2 25348397 N/A physical interaction ComPPI
TGFBR2 TRAF4 25348397 N/A physical interaction ComPPI
TGFBR2 PIK3CB 25348397 N/A physical interaction ComPPI
TGFBR2 CDC6 25348397 N/A physical interaction ComPPI
TGFBR2 PKN3 25348397 N/A physical interaction ComPPI
TGFBR2 PLEKHH3 25348397 N/A physical interaction ComPPI
TGFBR2 ACVR2B 25348397 N/A physical interaction ComPPI
TGFBR2 ACVR2A 25348397 N/A physical interaction ComPPI
TGFBR2 PKN2 25348397 N/A physical interaction ComPPI
TGFBR2 JAK1 25348397 N/A physical interaction ComPPI
TGFBR2 PIK3R3 25348397 N/A physical interaction ComPPI
TGFBR2 LSR 25348397 N/A physical interaction ComPPI
TGFBR2 RAB6B 25348397 N/A physical interaction ComPPI
TGFBR2 RAB6A 25348397 N/A physical interaction ComPPI
TGFBR2 WDR44 25348397 N/A physical interaction ComPPI
TGFBR2 MARCHF7 25348397 N/A physical interaction ComPPI
TGFBR2 CD320 25348397 N/A physical interaction ComPPI
TGFBR2 RELT 25348397 N/A physical interaction ComPPI
TGFBR2 BMPR1A 25348397 N/A physical interaction ComPPI
TGFBR2 DENND6A 25348397 N/A physical interaction ComPPI
TGFBR2 FGFR1 25348397 N/A physical interaction ComPPI
TGFBR2 DIP2A 25348397 N/A physical interaction ComPPI
TGFBR2 PTPRS 25348397 N/A physical interaction ComPPI
TGFBR2 PTPRF 25348397 N/A physical interaction ComPPI
TGFBR2 EHD4 25348397 N/A physical interaction ComPPI
TGFBR2 ACVR1B 25348397 N/A physical interaction ComPPI
TGFBR2 NDFIP1 25348397 N/A physical interaction ComPPI
TGFBR2 MFAP3 25348397 N/A physical interaction ComPPI
TGFBR2 MYADM 25348397 N/A physical interaction ComPPI
TGFBR2 SBF1 25348397 N/A physical interaction ComPPI
TGFBR2 FMN2 25348397 N/A physical interaction ComPPI
TGFBR2 FAM171A2 25348397 N/A physical interaction ComPPI
TGFBR2 LRP10 25348397 N/A physical interaction ComPPI
TGFBR2 CTDNEP1 25348397 N/A physical interaction ComPPI
TGFBR2 SPSB1 25348397 N/A physical interaction ComPPI
TGFBR2 RASSF1 25348397 N/A physical interaction ComPPI
TGFBR2 TRIM25 25348397 N/A physical interaction ComPPI
TGFBR2 LRG1 23868260 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TGFBR2 FSTL1 20860622 24234451 25348397 N/A surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
TGFBR2 SHC1 17440088 24234451 25348397 association coimmunoprecipitation ComPPI,IntAct
TGFBR2 SCUBE3 21441952 24234451 25348397 association,physical association anti tag coimmunoprecipitation,protein array,pull down ComPPI,IntAct
TGFBR2 MED12 23178117 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct,OmniPath
TGFBR2 TRMO 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFBR2 FANCC 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFBR2 MAP2K1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFBR2 PPP2CB 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TGFBR2 ZNF510 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
IQGAP1 TGFBR2 25348397 N/A physical interaction ComPPI
TGFBR2 TGFBR2 11163210 11279102 14525934 7890683 N/A experimental interaction detection,two hybrid HPRD
CDK1 TGFBR2 14525934 9926943 N/A experimental interaction detection HPRD
TGFBR2 TSSK1B 14525934 15761153 N/A experimental interaction detection HPRD
OSR1 TGFBR2 14525934 15761153 N/A experimental interaction detection HPRD
TGFBR2 SP6 19088080 24234451 association chromatin immunoprecipitation assay IntAct
TGFBR2 H4C1 19088080 24234451 association chromatin immunoprecipitation assay IntAct
TGFBR2 SIN3A 19088080 24234451 association chromatin immunoprecipitation assay IntAct
SRC TGFBR2 17440088 18174260 19114990 24983314 27898060 stimulant N/A OmniPath
TGFBR2 PIK3R2 26186194 27898060 9435577 stimulant N/A OmniPath
TGFBR2 MAP3K7 16360132 27898060 stimulant N/A OmniPath
APP TGFBR2 21244100 21832049 27898060 N/A N/A OmniPath
TGFBR2 APP 21244100 21832049 27898060 N/A N/A OmniPath
TGFBR2 TRAF6 18922473 19114990 26807171 27898060 stimulant N/A OmniPath
GRB2 TGFBR2 18174260 27898060 N/A N/A OmniPath
HSP90AA1 TGFBR2 18591668 22848678 27898060 stimulant N/A OmniPath
DAXX TGFBR2 11483955 27898060 stimulant N/A OmniPath
TGFBR2 PIK3R1 19114990 26186194 27898060 9435577 stimulant N/A OmniPath
TGFB1 TGFBR2 10026191 11157754 11382746 12729750 12809600 1310899 15034927 18382895 20856203 20860622 21054789 21441952 26194464 27898060 7706250 7852346 7878020 7935686 8106553 8242742 9261125 stimulant N/A OmniPath
TGFBR2 CDK1 27898060 9926943 N/A N/A OmniPath
TGFBR2 SMAD2 15104092 27898060 8980228 stimulant N/A OmniPath
TGFBR2 BRCA1 10550055 27898060 N/A N/A OmniPath
DAB2 TGFBR2 11387212 27898060 stimulant N/A OmniPath
TGFBR2 TGFBR3 11323414 12809600 12958365 27898060 N/A N/A OmniPath
TGFBR1 TGFBR2 10026191 11102446 11483955 12809600 18243111 19556242 19758997 21791611 23868260 25825445 27898060 7774578 7878020 7890683 8576253 inhibition N/A OmniPath
TGFBR2 TGFBR1 10026191 11102446 11483955 12809600 18243111 19556242 19758997 21791611 23868260 25825445 26194464 27898060 7774578 7878020 7890683 8576253 stimulant N/A OmniPath
TGFBR2 SMAD3 15104092 27898060 8774881 stimulant N/A OmniPath
TGFBR2 ZFYVE9 27898060 9865696 stimulant N/A OmniPath
TGFBR2 EIF3I 11781097 27898060 7566156 stimulant N/A OmniPath
EIF3I TGFBR2 11781097 27898060 7566156 9774674 stimulant N/A OmniPath
ENG TGFBR2 12015308 15702480 16785228 27898060 9872992 N/A N/A OmniPath
TGFBR2 ENG 12015308 15702480 16785228 27898060 9872992 stimulant N/A OmniPath
TGFB3 TGFBR2 11157754 11382746 11850637 12729750 15017149 16446785 18243111 21423151 27898060 7878020 8106553 9872992 stimulant N/A OmniPath
TGFBR2 TGFB3 11157754 11382746 11850637 12729750 15017149 16446785 18243111 21423151 27898060 7878020 8106553 9872992 inhibition N/A OmniPath
SMURF2 TGFBR2 11163210 22298955 25149540 27898060 inhibition N/A OmniPath
TGFB2 TGFBR2 11157754 1310899 1644679 27898060 8106553 stimulant N/A OmniPath
SMURF1 TGFBR2 11278251 22298955 27898060 inhibition N/A OmniPath
TGFBR2 PARD6A 15761148 23249950 27898060 stimulant N/A OmniPath
TGFBR2 ACVRL1 10187774 10716993 18333754 23868260 27898060 N/A N/A OmniPath

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