Gene Information gene info

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GENE：PSME1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSME1
FullNmae proteasome activator subunit 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9568
EnsembleID ENSG00000092010
Uniprot Q06323

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSME1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSME1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PSME1 GO:0000502,GO:0005515,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0008537,GO:0010950,GO:0019884,GO:0061133,GO:0061136,GO:0070062,GO:2000045

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSME1 hsa:5720 path:hsa03050 Proteasome - Homo sapiens (human)
PSME1 hsa:5720 path:hsa04612 Antigen processing and presentation - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PSME1 IL7R 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PSME1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PSME1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HNF4A PSME1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 PSME1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00004505E4 PSME1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D PSME1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC PSME1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 PSME1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PSME2 PSME1 25361965 interaction type N/A PTMCode2
PSME1 PSME2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
AIMP2 PSME1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PSMB10 PSME1 25348397 N/A physical interaction ComPPI
GPX7 PSME1 25348397 N/A physical interaction ComPPI
PAK2 PSME1 25348397 N/A physical interaction ComPPI
PPP1CC PSME1 25348397 N/A physical interaction ComPPI
BAG3 PSME1 25348397 N/A physical interaction ComPPI
VIM PSME1 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
KIF5B PSME1 25348397 N/A physical interaction ComPPI
TK1 PSME1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EMD PSME1 25348397 N/A physical interaction ComPPI
PSMD14 PSME1 25348397 N/A physical interaction ComPPI
NUBP2 PSME1 25348397 N/A physical interaction ComPPI
MCM2 PSME1 25348397 N/A physical interaction ComPPI
SMN1 PSME1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PSMB2 PSME1 25348397 N/A physical interaction ComPPI
UBL7 PSME1 25348397 N/A physical interaction ComPPI
SETDB1 PSME1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GRB2 PSME1 25348397 N/A physical interaction ComPPI
CTRL PSME1 25348397 N/A physical interaction ComPPI
RBBP6 PSME1 25348397 N/A physical interaction ComPPI
PSMA3 PSME1 25348397 N/A physical interaction ComPPI
U2AF2 PSME1 25348397 N/A physical interaction ComPPI
TUBG1 PSME1 25348397 N/A physical interaction ComPPI
PIK3R3 PSME1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ITGB3BP PSME1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PSMA1 PSME1 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PSMA6 PSME1 25348397 N/A physical interaction ComPPI
PSMB9 PSME1 25348397 N/A physical interaction ComPPI
VCL PSME1 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EIF6 PSME1 25348397 N/A two hybrid,physical interaction ComPPI
PSMB8 PSME1 25348397 N/A physical interaction ComPPI
PSMD1 PSME1 25348397 N/A physical interaction ComPPI
PSMC5 PSME1 25348397 N/A physical interaction ComPPI
HUWE1 PSME1 25348397 N/A physical interaction ComPPI
ATP1B1 PSME1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CYP1A1 PSME1 25348397 N/A physical interaction ComPPI
NAA10 PSME1 23624078 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMC4 PSME1 25348397 N/A physical interaction ComPPI
TUBB4B PSME1 25348397 N/A two hybrid,physical interaction ComPPI
CSE1L PSME1 25348397 N/A physical interaction ComPPI
PRKN PSME1 25348397 N/A physical interaction ComPPI
PARVB PSME1 25348397 N/A physical interaction ComPPI
CDC37 PSME1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SEM1 PSME1 24234451 24811749 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GARS1 PSME1 25348397 N/A physical interaction ComPPI
PSME1 PSME2 16189514 24234451 25348397 physical association physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,in vivo,two hybrid prey pooling approach ComPPI,IntAct
PSME1 EMG1 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PSME1 PFDN1 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PSME1 USP22 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PSME1 CHD3 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PSME1 RPP14 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PSME1 PSMC1 25348397 N/A physical interaction ComPPI
PSME1 PSMA2 25348397 N/A physical interaction ComPPI
PSME1 PSMB6 25348397 N/A physical interaction ComPPI
PSME1 PSMA4 25348397 N/A physical interaction ComPPI
PSME1 PSMD6 25348397 N/A physical interaction ComPPI
PSME1 PSMB7 25348397 N/A physical interaction ComPPI
PSME1 APP 25348397 N/A physical interaction ComPPI
PSME1 PSMC2 25348397 N/A physical interaction ComPPI
PSME1 PSMA7 25348397 N/A physical interaction ComPPI
PSME1 PSMD12 25348397 N/A physical interaction ComPPI
PSME1 OXCT1 25348397 N/A physical interaction ComPPI
PSME1 PSRC1 25348397 N/A physical interaction ComPPI
PSME1 USP5 25348397 N/A physical interaction ComPPI
PSME1 PHPT1 25348397 N/A physical interaction ComPPI
PSME1 PRDX3 25348397 N/A physical interaction ComPPI
PSME1 SEM1 25348397 N/A physical interaction ComPPI
PSME1 RNF26 25348397 N/A physical interaction ComPPI
PSME1 SCLT1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PSME1 FBXO7 25348397 N/A physical interaction ComPPI
PSME1 CDK15 25348397 N/A physical interaction ComPPI
PSME1 GJB4 25348397 N/A physical interaction ComPPI
PSME1 PSMG2 25348397 N/A physical interaction ComPPI
PSME1 TUBB2A 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PSME1 DUX4 24234451 25348397 26816005 association pull down ComPPI,IntAct
PSMB4 PSME1 25348397 N/A physical interaction ComPPI
PSMB1 PSME1 25348397 N/A physical interaction ComPPI
PSMB3 PSME1 25348397 N/A physical interaction ComPPI
DDX19B PSME1 25348397 N/A physical interaction ComPPI
ADRM1 PSME1 25348397 N/A physical interaction ComPPI
PSME1 PSME1 16169070 24234451 25416956 physical association two hybrid array,two hybrid pooling approach IntAct
BRAF PSME1 27898060 9679960 N/A N/A OmniPath
IL7R PSME1 20167604 27898060 N/A N/A OmniPath
IFNG PSME1 27898060 8051173 N/A N/A OmniPath

Visualization










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